Results 91 to 100 of about 63,038 (316)

On the use of the boundary layer integral equations for the prediction of skin friction and heat transfer [PDF]

open access: yes, 1986
The usefulness of the energy equation integrated over the thickness of the boundary layer, in predicing heat transfer rates to smooth body surfaces in investigated.
Hellon, C. S.
core  

Measurements of flows over isolated valleys [PDF]

open access: yes, 2005
Wind-tunnel measurements of the flow over an isolated valley both normal and at an angle (45°) to a simulated neutrally stable atmospheric boundary layer are presented. Attention is concentrated on the nature of the flow within the valley itself.
Brian Garvey   +7 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Concerning marginal singularities in the boundary-layer flow on a downstream-moving surface

open access: yes, 1996
The formation of separation singularities in solutions of the classical boundary-layer equations is studied numerically and analytically for the case of a two-dimensional incompressible steady flow near a solid surface moving in the direction of the main
Timoshin, SN
core  

Numerical Study on the Influence of Inlet Turbulence Intensity on Turbine Cascades

open access: yesAerospace
The turbulence intensity of the high-pressure turbine inlet plays an important role in the development of secondary flow and boundary layer evolution in the turbine passage.
Xuan Wu   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Unsteady separation past moving surfaces

open access: yes, 1998
Unsteady boundary-layer development over moving walls in the limit of infinite Reynolds number is investigated using both the Eulerian and Lagrangian formulations.
Degani, AT, Smith, FT, Walker, JDA
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Unsteadiness in shock-wave/boundary layer interactions

open access: yes, 2010
The need for better understanding of the low-frequency unsteadiness observed in shockwave/turbulent boundary layer interactions has been driving research in this area forseveral decades.
Touber, Emile
core  

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