Results 81 to 90 of about 63,038 (316)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
On the merging of turbulent spots in a supersonic boundary-layer flow
, 2005 The complex transition flow physics associated with the merging of turbulent spots in a Mach 2 boundary-layer has been studied using direct numerical simulation. Dynamics of an isolated turbulent spot, merging of laterally displaced spots, and merging of
Krishnan, L., Sandham, N.D.
core +1 more source
Numerical Investigation of Jet Angle Effect on Airfoil Stall Control
Applied Sciences, 2019 Numerical study on flow separation control is conducted for a stalled airfoil with steady-blowing jet. Stall conditions relevant to a rotorcraft are of interest here.
Junkyu Kim +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Large scale separation flow control experiments within the German Flow Control Network
, 2009 This is an overview on flow control experiments for flow separation control conducted in the DNW-NWB atmospheric low-speed wind tunnel performed within the German Flow Control Network. Emphasis is given on the experimental setup using the DLR F15 wall-to-
Wild, Jochen +9 more
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Incipient Separation for Hypersonic Shock Wave/Turbulent Boundary Layer Interaction
气体物理Shock/turbulent boundary layer interaction (STBLI) is a prevalent and complex flow phenomenon in the aerospace sector that significantly impacts the aerodynamic performance of vehicles.
Haodong WANG, Bowen ZHU, Lin BAO
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Control of shock-induced boundary layer separation at supersonic speeds
, 2007 PhDThe results of a systematic experimental investigation into the effects that Sub- Boundary Layer Vortex Generators (SBVGs) have on reducing normal shock-induced turbulent boundary layer separation are presented.
Cohen, Giel S, Cohen, Giel S.
core
Direct numerical simulation of a decelerated wall-bounded turbulent shear flow [PDF]
, 2003 A fully developed turbulent channel flow is subjected to a mean strain that approximates that in a spatially developing adverse-pressure-gradient (APG) boundary layer. This is done by applying uniform irrotational temporal deformations to the flow domain
Coleman, G.N., Spalart, P.R., Kim, J.
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FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source