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Optimal Simultaneous Confidence Bounds
Let the real random variable \(y=y(x)\), \(x\in X\subset R^ k\), be modeled as \(y=m(x)+e\), in which \(Ee=0\), Var e\(=\sigma^ 2\), unknown, and m is an unknown member of a given family of functions on X. It is assumed that as a result of observations on y at \(x_ 1,...,x_ n\in X\) there is available an estimator \^m(x) of m(x), \(x\in X\), and an ...
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Confidence bounds for a parameter
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Bentkus, V., Pap, Gyula, van Zuijlen, M.
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ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
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Opinion polarization, echo chambers, and the rapid formation of opinion clusters have become defining features of debates on contemporary online social platforms.
Zumei Huang +3 more
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In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Three-Stage Cascade Information Attenuation for Opinion Dynamics in Social Networks
In social network analysis, entropy quantifies the uncertainty or diversity of opinions, reflecting the complexity of opinion dynamics. To enhance the understanding of how opinions evolve, this study introduces a novel approach to modeling opinion ...
Haomin Wang, Youyuan Li, Jia Chen
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The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
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Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
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Opinion dynamics in relative agreement models seen as an extension of bounded confidence ones, involve a new agents’ variable usually called opinion uncertainty and have higher level of complexity than that of bounded confidence models.
Evguenii Kurmyshev +1 more
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