Network effects in a bounded confidence model
, 2022 International audienceThe bounded confidence model has become a popular tool for studying communities of epistemically interacting agents. The model makes the idealizing assumption that all agents always have access to all other agents’ belief states. We
Douven, Igor, Hegselmann, Rainer
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Confidence Intervals for the Coefficient of Variation in a Normal Distribution with a Known Mean and a Bounded Standard Deviation [PDF]
, 2017 The natural parameter space is known to be bounded in many real applications such as engineering, science and social science. The standard confidence interval derived from the classical Neyman procedure is unsatisfactory in the case of a bounded ...
Panichkitkosolkul, Wararit;
Department of Mathematics and Statistics, Faculty of Science and Technology, Thammasat University, Pathum Thani, Thailand
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Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Smoothed Bounded-Confidence Opinion Dynamics on the Complete Graph [PDF]
, 2022 We present and analyze a model for how opinions might spread throughout a network of people sharing information. Our model is called the smoothed bounded-confidence model and is inspired by the bounded-confidence model of opinion dynamics proposed by ...
Valore-Caplan, Solomon
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Opinion Dynamics and Bounded Confidence Models, Analysis and Simulation [PDF]
When does opinion formation within an interacting group lead to consensus, polarization or fragmentation? The article investigates various models for the dynamics of continuous opinions by analytical methods as well as by computer simulations.
Ulrich Krause, Rainer Hegselmann
core
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Confidence intervals for the difference and the ratio of Lognormal means with bounded parameters [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2015 In this paper, confidence intervals for the difference between lognormal means and the ratio of lognormal means with restricted parameter spaces are proposed.
Sa-aat Niwitpong
doaj
Confidence predicts speed-accuracy tradeoff for subsequent decisions
eLife, 2019 When external feedback about decision outcomes is lacking, agents need to adapt their decision policies based on an internal estimate of the correctness of their choices (i.e., decision confidence).
Kobe Desender +3 more
doaj +1 more source