Results 101 to 110 of about 126,431 (269)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Multivalence of bivariate functions of bounded index
Le Matematiche, 2015 This paper examines the relationship between the concept of bounded index and the radius of equivalence, respectively p-valence, of entire bivariate functions and their partial derivatives at arbitrary points in C^2.
Fatih Nuray, Richard F. Patterson
doaj
New Approximation Formula of Digamma Function with Bounded Remainder
MathematicsThis study establishes the new approximation formula for the Digamma function ψ(s)=lns−12s−112ss2+θ(s ...
Mansour Mahmoud +2 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Solutions to Lyapunov stability problems: nonlinear systems with continuous motions
International Journal of Mathematics and Mathematical Sciences, 1994 The necessary and sufficient conditions for accurate construction of a Lyapunov function and the necessary and sufficient conditions for a set to be the asymptotic stability domain are algorithmically solved for a nonlinear dynamical system with ...
Ljubomir T. Grujic
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On the relaxation of some classes of unbounded integral functionals
Le Matematiche, 1996 Given a Borel function having convex effective domain, but not necessarily bounded or with nonempty interior, locally bounded in the relative interior of its effective domain and verifying an upper semicontinuity type assumption in its effective domain ...
Luciano Carbone, Riccardo De Arcangelis
doaj
A degree bound for planar functions
Combinatorial TheoryThis is the version accepted for publication in Combinatorial ...
Beierle, Christof, Beyne, Tim
openaire +3 more sources