Results 111 to 120 of about 1,239,655 (312)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A new proof of the Krzyz conjecture for n = 3 [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Математика. Механика. Информатика
The purpose of this paper is to solve the problem of the sharp estimation of the modulus of the third Taylor coefficient on the class of holomorphic bounded nonvanishing in the unit disk functions (hereafter referred to as the class of bounded ...
Stupin, Denis Leonidovich
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Estimation of Scale Parameter Under a Bounded Loss Function [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2016
The quadratic loss function has been used by decision-theoretic statisticians and economists for many years.  In this paper  the estimation of scale parameter under a bounded loss function, which is adequate for assessing quality and quality improvement,
N. Sanjari Farsipour
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Multilinear Square Functions with Kernels of Dini’s Type

open access: yesJournal of Function Spaces, 2016
Let T be a multilinear square function with a kernel satisfying Dini(1) condition and let T⁎ be the corresponding multilinear maximal square function. In this paper, first, we showed that T is bounded from L1×⋯×L1 to L1/m,∞. Secondly, we obtained that if
Zengyan Si, Qingying Xue
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Uniformly bounded superposition operators in the space of second bounded variation functions in the sense of Shiba

open access: yesPublicaciones en Ciencias y Tecnología, 2016
In this paper we introduce the notion of “function of second bounded variation” in the sense of Shiba, and we show that if a superposition operator applies the space of all such functions on itself and it is uniformly bounded, then its generating ...

doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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