Results 111 to 120 of about 1,239,655 (312)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
A new proof of the Krzyz conjecture for n = 3 [PDF]
The purpose of this paper is to solve the problem of the sharp estimation of the modulus of the third Taylor coefficient on the class of holomorphic bounded nonvanishing in the unit disk functions (hereafter referred to as the class of bounded ...
Stupin, Denis Leonidovich
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Estimation of Scale Parameter Under a Bounded Loss Function [PDF]
The quadratic loss function has been used by decision-theoretic statisticians and economists for many years. In this paper the estimation of scale parameter under a bounded loss function, which is adequate for assessing quality and quality improvement,
N. Sanjari Farsipour
doaj
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Multilinear Square Functions with Kernels of Dini’s Type
Let T be a multilinear square function with a kernel satisfying Dini(1) condition and let T⁎ be the corresponding multilinear maximal square function. In this paper, first, we showed that T is bounded from L1×⋯×L1 to L1/m,∞. Secondly, we obtained that if
Zengyan Si, Qingying Xue
doaj +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
In this paper we introduce the notion of “function of second bounded variation” in the sense of Shiba, and we show that if a superposition operator applies the space of all such functions on itself and it is uniformly bounded, then its generating ...
doaj
Fast rates for empirical risk minimization over càdlàg functions with bounded sectional variation norm [PDF]
Aurélien Bibaut, Mark J. van der Laan
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source

