Results 111 to 120 of about 1,242,956 (315)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Coefficients estimates of some subclasses of analytic functions related with conic domain

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
In this paper, the authors determine the coefficient bounds for functions in certain subclasses of analytic functions related with the conic regions, which are introduced by using the concept of bounded boundary and bounded radius rotations.
Malik Sarfraz Nawaz, Raza Mohsan, Arif Muhammad, Hussain Saqib   +3 more
doaj   +1 more source

A Combinatorial, Strongly Polynomial-Time Algorithm for Minimizing Submodular Functions

, 2000
This paper presents the first combinatorial polynomial-time algorithm for minimizing submodular set functions, answering an open question posed in 1981 by Grotschel, Lovasz, and Schrijver.
Fleischer, Lisa, Fujishige, Satoru, Iwata, Satoru   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A new proof of the Krzyz conjecture for n = 3 [PDF]

Известия Саратовского университета. Новая серия: Математика. Механика. Информатика
The purpose of this paper is to solve the problem of the sharp estimation of the modulus of the third Taylor coefficient on the class of holomorphic bounded nonvanishing in the unit disk functions (hereafter referred to as the class of bounded ...
Stupin, Denis Leonidovich
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Estimation of Scale Parameter Under a Bounded Loss Function [PDF]

Journal of Sciences, Islamic Republic of Iran, 2016
The quadratic loss function has been used by decision-theoretic statisticians and economists for many years.  In this paper  the estimation of scale parameter under a bounded loss function, which is adequate for assessing quality and quality improvement,
N. Sanjari Farsipour
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Multilinear Square Functions with Kernels of Dini’s Type

Journal of Function Spaces, 2016
Let T be a multilinear square function with a kernel satisfying Dini(1) condition and let T⁎ be the corresponding multilinear maximal square function. In this paper, first, we showed that T is bounded from L1×⋯×L1 to L1/m,∞. Secondly, we obtained that if
Zengyan Si, Qingying Xue
doaj   +1 more source

Certain classes of bi-univalent functions with bounded boundary variation [PDF]

, 2017
Halit Orhan, N. Magesh, V. K. Balaji
openalex   +1 more source