Results 61 to 70 of about 1,242,956 (315)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Integral Representation of Functions of Bounded Variation

open access: yesJournal of Mathematics, 2019
Functions of bounded variations form important transition between absolute continuous and singular functions. With Bainov’s introduction of impulsive differential equations having solutions of bounded variation, this class of functions had eventually ...
Z. Lipcsey   +3 more
doaj   +1 more source

Bounded functional interpretation

open access: yesAnnals of Pure and Applied Logic, 2005
Gödel's Dialectica interpretation is suitable for extracting precise witnesses from constructive proofs of existential statements (or more generally of \(\forall \exists\)-statements). In the present paper, the authors present a new functional interpretation -- the so called \textit{bounded functional interpretation}, b.f.i. henceforth -- which aims at
Ferreira, Fernando, Oliva, Paulo
openaire   +2 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Parameterized inequalities based on three times differentiable functions

open access: yesBoundary Value Problems
This paper presents a general identity including two real parameters for three times differentiable functions. By using this equality, we prove several inequalities by using diverse function classes such as convex function, bounded function, Lipschitzian
Bouharket Benaissa   +2 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The product and existence theorems for analytic functions in a polydisc of bounded $L$-index in direction

open access: yesResearches in Mathematics
For functions analytic in the unit polydisc with bounded $L$-index in a direction there are presented three various results. The product theorem specifies that the product of analytic functions of bounded $L$-index in direction belongs to the same class.
A.I. Bandura   +4 more
doaj   +1 more source

Slice Holomorphic Functions in the Unit Ball Having a Bounded L-Index in Direction

open access: yesAxioms, 2020
Let b∈Cn\{0} be a fixed direction. We consider slice holomorphic functions of several complex variables in the unit ball, i.e., we study functions that are analytic in the intersection of every slice {z0+tb:t∈C} with the unit ball Bn={z∈C:|z|:=|z|12 ...
Andriy Bandura   +2 more
doaj   +1 more source

AN EXISTENCE AND UNIQUENESS OF THE SOLUTION OF SEMILINEAR MONOTONE ELLIPTIC EQUATION WITH THE DATA IN STUMMEL CLASSES

open access: yesBarekeng, 2023
Let  be a bounded open subset of , ,  be a function in Stummel classes , where , and be a semilinear monotone elliptic equation, where  is  symmetric matrix, elliptic, bounded, and  is non decreasing and Lipschitz. By proving a weighted estimation for
Nicky Kurnia Tumalun
doaj   +1 more source

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