Results 81 to 90 of about 1,242,956 (315)
ON ESTIMATES OF M-TERM APPROXIMATIONS ON CLASSES OF FUNCTIONS WITH BOUNDED MIXED DERIVATIVE IN THE LORENTZ SPACE [PDF]
Г. Акишев, A.Kh. Myrzagaliyeva
openalex +1 more source
Polynomial Threshold Functions, AC^0 Functions and Spectral Norms [PDF]
The class of polynomial-threshold functions is studied using harmonic analysis, and the results are used to derive lower bounds related to AC^0 functions.
Bruck, Jehoshua, Smolensky, Roman
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Application of continuum laws in discontinuity analysis based on a regularised displacement jump [PDF]
The application of continuum constitutive laws in embedded strong discontinuity analysis is examined. By adopting a regularised discontinuity (approximating the unbounded strain field resulting from a displacement jump with a bounded function), the ...
Sluys, LJ, Wells, GN
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In this paper, we consider the Nemytskii operator (Hf)(t) = h(t, f(t)), generated by a given function h. It is shown that if H is globally Lipschitzian and maps the space of functions of bounded (p,2,α)-variation (with respect to a weight function α ...
Aziz Wadie
doaj +1 more source
The measures with $L^2$-bounded Riesz transform and the Painlev\\'e\n problem for Lipschitz harmonic functions [PDF]
Xavier Tolsa
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

