Results 81 to 90 of about 1,223,914 (264)

The catalytic function of cytochrome P450 is entwined with its membrane-bound nature [PDF]

open access: gold, 2017
Carlo Barnaba   +3 more
openalex   +1 more source

Complexity and fractal dimensions for infinite sequences with positive entropy

open access: yes, 2017
The complexity function of an infinite word $w$ on a finite alphabet $A$ is the sequence counting, for each non-negative $n$, the number of words of length $n$ on the alphabet $A$ that are factors of the infinite word $w$.
Mauduit, Christian   +1 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Coefficients estimates of some subclasses of analytic functions related with conic domain

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
In this paper, the authors determine the coefficient bounds for functions in certain subclasses of analytic functions related with the conic regions, which are introduced by using the concept of bounded boundary and bounded radius rotations.
Malik Sarfraz Nawaz   +3 more
doaj   +1 more source

A new proof of the Krzyz conjecture for n = 3 [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Математика. Механика. Информатика
The purpose of this paper is to solve the problem of the sharp estimation of the modulus of the third Taylor coefficient on the class of holomorphic bounded nonvanishing in the unit disk functions (hereafter referred to as the class of bounded ...
Stupin, Denis Leonidovich
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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