Results 111 to 120 of about 6,452,940 (353)

A discrete Stochastic Korovkin theorem

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
In this article we give a sufficient condition for the pointwise −− in the first mean Korovkin property on B0(P), the space of stochastic processes with real state space and countable index set Γ and bounded first moments.
George A. Anastassiou
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Composition of entire function and analytic functions in the unit ball with a vanished gradient

open access: yesМатематичні Студії
The composition $H(z)=f(\Phi(z))$ is studied, where $f$ is an entire function of a single complex variable and $\Phi$ is an analytic function in the $n$-dimensional unit ball with a vanished gradient. We found conditions by the function $\Phi$ providing
A. I. Bandura, T. M. Salo, O. B. Skaskiv
doaj   +1 more source

Nonfragile Robust Finite-Time L2-L∞ Controller Design for a Class of Uncertain Lipschitz Nonlinear Systems with Time-Delays

open access: yesAbstract and Applied Analysis, 2013
The nonfragile robust finite-time L2-L∞ control problem for a class of nonlinear uncertain systems with uncertainties and time-delays is considered.
Jun Song, Shuping He
doaj   +1 more source

Fields with bounded Brauer 2-torsion index

open access: yesMathematische Annalen, 2023
It is shown that, over a field of characteristic not $2$, the dimension of an anisotropic quadratic Pfister form of trivial total signature is at most twice the dimension of some central division algebra of exponent $2$. The proof is based on computations with quadratic trace forms of central simple algebras.
openaire   +4 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Modelling Financial Risk in the South African Stock Market: An Application of the Generalised Extreme Value Distribution (GEVD)

open access: yesEconometric Research in Finance
This study analyses the return characteristics of the South African Industrial Index (J520) and South African Financial Index (J580) using the Generalized Extreme Value Distribution (GEVD) to estimate return levels, Value-at-Risk (VaR) and Expected ...
Owen Jakata, Delson Chikobvu
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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