Results 91 to 100 of about 56,141 (357)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

A new study on the strongly lacunary quasi Cauchy sequences

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
In this paper, the concept ofan -quasi-Cauchysequence is introduced. We proved interesting theorems related to -quasi-Cauchysequences. A real valued function defined on a subset of , the set of real numbers, is -ward continuous on if it preserves -quasi ...
Huseyin Cakalli, Hüseyin Kaplan
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Product metrics and boundedness

Applied General Topology, 2008
[EN] This paper looks at some possible ways of equipping a countable product of unbounded metric spaces with a metric that acknowledges the boundedness characteristics of the factors.
openaire   +4 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Criteria for the asymptotic behaviour of solutions to certain third-order nonlinear differential equations [PDF]

Mathematica Moravica
We investigate and provide sufficient criteria for ultimate boundedness of solutions as well as the asymptotic stability of the trivial solution to certain nonlinear differential equation of order three. Using the Lyapunov second method and the Yoshizawa
Adeyanju A.A., Fabelurin O.O., Akinbo G., Aduroja O.O., Ademola A.T., Ogundiran M.O., Ogundare B.S., Adesina O.A.   +7 more
doaj   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Stability and persistence in ODE modelsfor populations with many stages

Mathematical Biosciences and Engineering, 2015
A model of ordinary differential equations is formulated for populationswhich are structured by many stages. The model is motivated by tickswhich are vectors of infectious diseases, but is general enough to apply to many other species.Our analysis ...
Guihong Fan, Yijun Lou, Horst R. Thieme, Jianhong Wu   +3 more
doaj   +1 more source

Boundedness of fractional integrals on weighted Herz spaces with variable exponent

, 2016
Our aim is to prove the boundedness of fractional integral operators on weighted Herz spaces with variable exponent. Our method is based on the theory on Banach function spaces and the Muckenhoupt theory with variable exponent.
M. Izuki, T. Noi
semanticscholar   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source