Results 111 to 120 of about 140,249 (314)

Stability and boundedness In nonlinear and neutral difference equations using new variation of parameters formula and fixed point theory

open access: yesCubo, 2019
In the case of nonlinear problems, whether in differential or difference equations, it is difficult and in some cases impossible to invert the problem and obtain a suitable mapping that can be effectively used in fixed point theory to qualitatively ...
Youssef N. Raffoul
doaj   +1 more source

Product metrics and boundedness

open access: yesApplied General Topology, 2008
[EN] This paper looks at some possible ways of equipping a countable product of unbounded metric spaces with a metric that acknowledges the boundedness characteristics of the factors.
openaire   +4 more sources

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

On a system of $m$ difference equations having exponential terms

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2015
In this paper we study the asymptotic behavior of the positive solutions of a cyclic system of the following $m$ difference equations: \begin{align*} x^{(i)}_{n+1}&=a_ix_n^{(i+1)}+b_i x^{(i)}_{n-1}e^{{-x^{(i+1)}_n}},\qquad i=1,2,\ldots, m-1,\\ x^{(m)}_ ...
Garyfalos Papaschinopoulos   +2 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Duals of Gelfand-Shilov spaces of type $ K\{M_p\} $ for the Hankel transformation

open access: yesAIMS Mathematics
For $ \mu \geq-\frac{1}{2} $, and under appropriate conditions on the sequence $ \{M_p\}_{p = 0}^{\infty} $ of weights, the elements, the (weakly, weakly*, strongly) bounded subsets, and the (weakly, weakly*, strongly) convergent sequences in the dual of
Samuel García-Baquerín   +1 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Global bounded solution of a 3D chemotaxis-Stokes system with slow p-Laplacian diffusion and logistic source

open access: yesAIMS Mathematics
In this paper, the chemotaxis-Stokes system with slow $ p $-Laplacian diffusion and logistic source as follows $ \begin{equation*} \left\{ \begin{aligned} &n_t+u\cdot\nabla n = \nabla\cdot(|\nabla n|^{p-2}\nabla n)-\nabla\cdot(n\nabla c)+\mu n(
Xindan Zhou , Zhongping Li
doaj   +1 more source

The Boundedness of Marcinkiewicz Integral Associated with Schrödinger Operator and Its Commutator

open access: yesJournal of Function Spaces, 2014
The authors prove that Marcinkiewicz integral operator is not only are bounded on Lp, for ...
Dongxiang Chen, Dan Zou
doaj   +1 more source

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