Results 151 to 160 of about 187,605 (363)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Boundedness and long-time behavior in a parabolic-elliptic system arising from biological transport networks

Advances in Nonlinear Analysis
The aim of this article is to consider a three-dimensional Cauchy problem for the parabolic-elliptic system arising from biological transport networks. For such problem, we first establish the global existence, uniqueness, and uniform boundedness of the ...
Li Bin
doaj   +1 more source

Boundedness of the Riesz Potential in Generalized Morrey Spaces

, 2018
Hairur Rahman, Mohammad Imam Utoyo, Eridani Eridani   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Investigating Prospective Mathematics Teachers’ Understanding of the Boundedness of Infinite Number Sets

Ankara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi
In this study we aim to reveal the conceptions of preservice mathematics teachers regarding the boundedness of infinite number sets. The research is conducted with 51 teacher candidates attending to the Primary Mathematics Teaching program of a state ...
Tuba Sevyut, Yeter Şahiner
doaj   +1 more source

Boundedness of One Class of Integral Operators from Second Order Weighted Sobolev Space to Weighted Lebesgue Space [PDF]

, 2022
Aigerim Kalybay
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Global boundedness in a quasilinear predator–prey chemotaxis system with nonlinear indirect signal production

Electronic Journal of Qualitative Theory of Differential Equations
This paper deals with the quasilinear predator–prey chemotaxis system with nonlinear indirect signal production under homogeneous Neumann boundary conditions.
Zhangsheng Zhu
doaj   +1 more source

Spatial and temporal boundedness in English motion events

, 2004
Bert Cappelle, Renaat Declerck
openalex   +2 more sources

On Boundedness of Weighted Hardy Operator in and Regularity Condition [PDF]

, 2010
Aziz Harman, Farman Mamedov
openalex   +1 more source