Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang +25 more
wiley +1 more source
A case report of lameness in two dairy goat herds: a suspected combination of nutritional factors concurrent with treponeme infection [PDF]
Background: Two dairy goat farms with high level of lameness in lactating animals were presented for further investigation. Farm 1 and Farm 2 presented with 37 and 67 % morbidity, respectively.
Anzuino, Katharine +4 more
core +4 more sources
Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li +7 more
wiley +1 more source
Survey of interdigital phlegmon outbreaks and their risk factors in free stall dairy herds in Finland [PDF]
Background: Severe outbreaks of interdigital phlegmon (IP) associated with a high morbidity and major economic losses have occurred in Finland in the past decade.
Junni, Reijo +7 more
core +1 more source
Visually apparent diseases are valuable for investigating and monitoring the occurrence and prevalence of pathogens in wildlife populations through passive monitoring methods like camera trapping. Rumpwear is characterized by visible signs of hair breakage and damage on the lumbosacral region of common brushtail possums.
Elise M. Ringwaldt +3 more
wiley +1 more source
Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons. [PDF]
Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointestinal, and ...
Boback, Scott M +9 more
core +1 more source
ABSTRACT Background Bridging ancient herbal wisdom with modern biomaterial innovation, this study pioneers a smart hydrogel infused with Red Ginseng (RG) (angiogenesis‐boosting ginsenosides) and Centella asiatica (collagen‐stimulating asiaticoside), synergized with alginate and upcycled eggshell membrane for unrivaled wound adhesion and eco‐conscious ...
Samaneh Esmaeili +4 more
wiley +1 more source
Design and Characterization of a Transethosome‐Based Gel for Cutaneous Administration of Genistein
In this study, lipid nanovesicular systems such as ethosome and transethosome dispersions were studied as potential vehicles for the cutaneous administration of genistein, an isoflavone with antioxidant and chemopreventive properties. The lipophilicity of genistein requires specialized delivery systems suitable for transdermal administration. Genistein
Federico Santamaria +14 more
wiley +1 more source
Experimental infection of cattle with ovine Dichelobacter nodosus isolates [PDF]
BACKGROUND: Dichelobacter nodosus is the main causative agent of ovine footrot, and there are strong indications that the bacterium can be transferred to cattle grazing on the same pasture as sheep.
Fjeldaas, Terje +6 more
core +3 more sources
Genetic variation in dairy cattle claw health traits recorded by claw trimmers [PDF]
Claw health has been recorded by claw trimmers at trimming in Sweden since 1996, but data was then captured at each AI association. From 2003 data was captured by central scanning and entered directly to the national cow data base at the Swedish Dairy ...
Naeslund, Sandra
core +1 more source

