Results 81 to 90 of about 189,208 (196)

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Viroses confundíveis com febre aftosa Viral diseases to be differentiated from foot-and-mouth disease

Ciência Rural, 1996
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa, Valéria Moojen, Paulo Michel Roehe, Rudi Weiblen   +3 more
doaj   +1 more source

Characterization of a continuous feline mammary epithelial cell line susceptible to feline epitheliotropic viruses. [PDF]

, 2009
Mucosal epithelial cells are the primary targets for many common viral pathogens of cats. Viral infection of epithelia can damage or disrupt the epithelial barrier that protects underlying tissues.
Heymer, Anna, Liu, Hongwei, Millon, Lee, Ossiboff, Robert J, Parker, John SL, Pesavento, Patricia, Stucker, Karla M, van der List, Deborah, Wood, Jason   +8 more
core  

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara, Faggioni, Alberto, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Granato, Marisa, Romeo, Maria Anele, Santarelli, Roberta, Tiano, Mariangela Sara   +7 more
core   +2 more sources

Synthesis and processing of bovine herpesvirus-1 glycoprotein H

Virology, 1995
The translation product of the bovine herpesvirus-1 (BHV-1) gH gene was identified and characterized. Synthetic peptides were used to generate specific antisera and a glycoprotein of 108K was precipitated by one of the antisera. Cross-immunoprecipitations with monoclonal antibodies to BHV-1 glycoprotein gp108 and the anti-gH peptide antiserum ...
Baranowski, Eric, Dubuisson, Jean, van Drunen Little-van den Hurk, Sylvia, Babiuk, A. Lorne, Michel, Alain, Pastoret, Paul-Pierre, Thiry, Etienne   +6 more
openaire   +4 more sources

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

The FEBS Journal, Volume 293, Issue 4, Page 1024-1044, February 2026.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu, Noemi Nagy, Carlos Mario Ayala‐Torres, Maria G. Masucci   +3 more
wiley   +1 more source

Prevalence of Bovine Herpesvirus-1 in cattle and buffaloes in Punjab

Veterinary World, 2013
Aim: The aim of the present study was to identify the prevalence of Bovine Herpesvirus-1 (BHV-1) in cattle and buffaloes in the Punjab using PCR as diagnostic tool.
Gurpreet Kaur, P. N. Dwivedi, Ramneek Verma, N. S. Sharma   +3 more
doaj   +1 more source

Importance of Viral Disease in Dairy Cow Fertility

Engineering, 2020
Many viral diseases are endemic in cattle populations worldwide. The ability of many viruses to cross the placenta and cause abortions and fetal malformations is well understood.
D. Claire Wathes, Chike F. Oguejiofor, Carole Thomas, Zhangrui Cheng   +3 more
doaj   +1 more source

The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]

, 2019
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N, Coombs, Andrew J, Dellaire, Graham, Druley, Todd E, Ha, Michael N, McCormick, Craig, Melong, Nicole, O\u27Leary, David, Pringle, Eric S, Robinson, Carolyn-Ann, Veinotte, Chansey, Wertman, Jaime, Young, Andrew L   +12 more
core   +2 more sources

Unraveling Network Pharmacology‐Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Anthranilates sulfonamides (SA1–4) showed neuroprotective activity against human neuronal SH‐SY5Y cells under oxidative stress. The data represented significantly regulated sirtuins (SIRTs)/forkhead box class O 3a (FOXO3a)‐mediated longevity signaling pathway via targeting endogenous antioxidant enzymes, including superoxide dismutase 2 (SOD2) and ...
Waralee Ruankham, Veda Prachayasittikul, Ratchanok Pingaew, Wilasinee Jeungprasopsuk, Tanawut Tantimongcolwat, Virapong Prachayasittikul, Supaluk Prachayasittikul, Kamonrat Phopin   +7 more
wiley   +1 more source