Results 71 to 80 of about 3,259 (194)

Importance of continuous monitoring of bovine leukaemia virus infection on farms in bovine leukaemia virus‐endemic areas of Japan

Veterinary Record Open, Volume 12, Issue 2, December 2025.
Abstract Background Enzootic bovine leukosis (EBL), caused by the bovine leukaemia virus (BLV), has exhibited increasing infection rates in Japan. While many farms implement various infection prevention measures, practical challenges—such as barn structure and availability of replacement cattle—can hinder farm purification efforts.
Chikako Tani, Jiazhou Li, Hirohisa Mekata, Kazuhiro Morishita, Shingo Nakahata   +4 more
wiley   +1 more source

CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang, Qianqian Wang, Jiaming Zhang, Bingyu Li, Yuke Li, Zhengbo Chen, Dandan Guo, Shuying Feng   +7 more
wiley   +1 more source

Quantitative Risk Assessment for the Introduction of Bovine Leukemia Virus-Infected Cattle Using a Cattle Movement Network Analysis

Pathogens, 2020
The cattle industry is suffering economic losses caused by bovine leukemia virus (BLV) and enzootic bovine leukosis (EBL), the clinical condition associated with BLV infection.
Kosuke Notsu, Anuwat Wiratsudakul, Shuya Mitoma, Hala El Daous, Chiho Kaneko, Heba M. El-Khaiat, Junzo Norimine, Satoshi Sekiguchi   +7 more
doaj   +1 more source

A target enrichment high throughput sequencing system for characterization of BLV whole genome sequence, integration sites, clonality and host SNP

Scientific Reports, 2021
Bovine leukemia virus (BLV) is an oncogenic retrovirus which induces malignant lymphoma termed enzootic bovine leukosis (EBL) after a long incubation period.
Nagaki Ohnuki, Tomoko Kobayashi, Misaki Matsuo, Kohei Nishikaku, Kazuya Kusama, Yasushi Torii, Yasuko Inagaki, Masatoshi Hori, Kazuhiko Imakawa, Yorifumi Satou   +9 more
doaj   +1 more source

The microbiome in cancer

iMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin, Minying Xiong, Aimin Jiang, Lihaoyun Huang, Hank Z. H. Wong, Suyin Feng, Chunyan Zhang, Yu Li, Li Chen, Hao Chi, Pengpeng Zhang, Bicheng Ye, Hengguo Zhang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Junyi Shen, Kailai Li, Wentao Xu, Haoxuan Ying, Cangang Zhang, Dongqiang Zeng, Jindong Xie, Xinpei Deng, Qi Wang, Jianying Xu, Wenjie Shi, Chang Qi, Chunrun Qu, Xufeng Huang, András Hajdu, Chaoqun Li, Changmin Peng, Xuanye Cao, Guangsheng Pei, Lin Zhang, Yujia Huo, Jiabao Xu, Antonino Glaviano, Attila Gábor Szöllősi, Sicheng Bian, Zhengrui Li, Hailin Tang, Bufu Tang, Zaoqu Liu, Jian Zhang, Kai Miao, Quan Cheng, Ting Wei, Shuofeng Yuan, Peng Luo   +50 more
wiley   +1 more source

A survey for maternal antibodies to bovine leukemia virus (BLV) in calves born to cows infected with BLV.

The Japanese Journal of Veterinary Science, 1984
Seventy calves born to the cows infected with bovine leukemia virus (BLV) were examined periodically for the maternal antibodies to BLV. Antibodies to BLV were negative in all of 22 except one calves examined at precolostrum stage, but they converted into positive 24hrs postcolostrum. Most of the 70 calves being positive in the antibodies to BLV at the
OHSHIMA, Kan-ichi, MORIMOTO, Naoko, KAGAWA, Yuichi, NUMAKUNAI, Shigeru, HIRANO, Teruo, KAYANO, Hiroshi   +5 more
openaire   +3 more sources

Multicentric lymphomas in goats (Capra hircus): Clinical manifestations, therapeutic modalities and pathological characteristics

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract Two cases of sporadic multicentric lymphomas with mediastinal masses in goats are documented. The first case involved a 3.5‐year‐old male goat. Ultrasound imaging revealed an enlarged right perirenal lymph node, which was confirmed as lymphoma through incisional biopsy and cytopathological analysis. Despite treatment, the goat succumbed to the
Angélica Consalter, Mateus de Melo Lima Waterloo, Juliana Mariotti Guerra, Ana Maria Reis Ferreira, Juliana da Silva Leite, Kassia Valéria Gomes Coelho da Silva, Mário Felipe Alvarez Balaro   +6 more
wiley   +1 more source

Preventive and Therapeutic Strategies for Bovine Leukemia Virus: Lessons for HTLV

Viruses, 2011
Bovine leukemia virus (BLV) is a retrovirus closely related to the human T-lymphotropic virus type 1 (HTLV-1). BLV is a major animal health problem worldwide causing important economic losses.
Lucas Vagnoni, Fanny Boulanger, Gerónimo Gutiérrez, Karina Trono, Irene Alvarez, Mathieu Boxus, María Teresa Sánchez-Alcaraz, Nicolas Gillet, Alix De Brogniez, Arnaud Florins, Sabrina M. Rodríguez, Luc Willems   +11 more
doaj   +1 more source

Circulating Cell‐Free DNA of Bovine Leukemia Virus: A Promising Biomarker for Enzootic Bovine Leukosis

Microbiology and Immunology, Volume 69, Issue 9, Page 466-476, September 2025.
ABSTRACT Bovine leukemia virus (BLV) causes Enzootic bovine leukosis (EBL) in approximately 1%–5% of infected cattle after a long latent period. Few biomarkers effectively distinguish non‐EBL from EBL cattle. Given the rapid turnover of tumor cells, we hypothesized that cell‐free DNA (cfDNA) in plasma could serve as a more effective biomarker for EBL ...
M. Ishrat Jahan, Toshiaki Inenaga, Sakurako Makimoto, Md. Belal Hossain, Yuka Matsuoka, Sharmin Nahar Sithi, Samiul Alam Rajib, Arif Nur Muhammad Ansori, Kenji Sugata, Kazuhiko Imakawa, Tomoko Kobayashi, Yorifumi Satou   +11 more
wiley   +1 more source

Multivariate Effects of SNPs on Environmental Streptococcal Mastitis Evaluated With an NGS‐Based Association Study Using Targeted Resequencing in the Bovine MHC Region

HLA, Volume 106, Issue 1, July 2025.
ABSTRACT Mastitis is an inflammatory reaction caused by bacterial infection of the teat, and a relationship between its onset and cattle major histocompatibility complex (BoLA) region has been reported. However, no comprehensive genetic analysis of mastitis caused by environmental streptococci has been reported.
Fumihiro Nagata, Chieh‐Wen Lo, Susumu Saito, Ryosuke Matsuura, Sonoko Watanuki, Kazuyoshi Hosomichi, Shinji Sasaki, Ryusaku Kawata, Hiroyuki Shimizu, Takahiro Sone, Haruna Yamazaki, Ayuha Niwano, Kazuhiro Kawai, Tetsuya Mizutani, Yasunobu Matsumoto, Shin‐nosuke Takeshima, Yoko Aida   +16 more
wiley   +1 more source