Results 61 to 70 of about 2,436 (166)

Comparative Evaluation of Three Commercial Quantitative Real-Time PCRs Used in Japan for Bovine Leukemia Virus

Viruses, 2022
Bovine leukemia virus (BLV) is an oncogenic virus belonging to the genus Deltaretrovirus and is the causative agent of enzootic bovine leukosis. Proviral load (PVL) determined by real-time quantitative PCR (qPCR) is now widely used as an indicator of not
Syuji Yoneyama, Sota Kobayashi, Towa Matsunaga, Kaoru Tonosaki, Dongze Leng, Yusuke Sakai, Shinji Yamada, Atsushi Kimura, Toshihiro Ichijo, Hirokazu Hikono, Kenji Murakami   +10 more
doaj   +1 more source

Bovine leukemia virus (BLV) specific RNA in infected cells.

Annales de recherches veterinaires. Annals of veterinary research, 1978
BLV specific RNA sequences were detected by hybridization to the single stranded DNA copy of the viral RNA in fetal lamb kidney cells infected with bovine leukemia virus (FLK-BLV). The DNA synthesis was carried out in vitro by an endogenous reaction. It was found that uninfected lamb cells do not contain RNA sequences related to the BLV genome, whereas
Astier, T., Mamoun, R., Guillemain, B., Duplan, J.F., Parodi, A.L.   +4 more
openaire   +2 more sources

Establishment and Characterization of Human Cell Lines Stably Infected With Bovine Leukemia Virus In Vitro Reveals Apoptosis After Latency and Silencing

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Bovine leukemia virus (BLV) is the etiological agent of B‐cell leukemia/lymphoma in cattle worldwide. Although previous studies have linked BLV to breast cancer in women, its zoonotic potential remains controversial. Moreover, no previous studies have clearly investigated the BLV latency in human cells.
Samy Metwally, Rania Hamada, Ryosuke Matsuura, Yoko Aida, Efstathios Giotis S   +4 more
wiley   +1 more source

Importance of continuous monitoring of bovine leukaemia virus infection on farms in bovine leukaemia virus‐endemic areas of Japan

Veterinary Record Open, Volume 12, Issue 2, December 2025.
Abstract Background Enzootic bovine leukosis (EBL), caused by the bovine leukaemia virus (BLV), has exhibited increasing infection rates in Japan. While many farms implement various infection prevention measures, practical challenges—such as barn structure and availability of replacement cattle—can hinder farm purification efforts.
Chikako Tani, Jiazhou Li, Hirohisa Mekata, Kazuhiro Morishita, Shingo Nakahata   +4 more
wiley   +1 more source

Preventive and Therapeutic Strategies for Bovine Leukemia Virus: Lessons for HTLV

Viruses, 2011
Bovine leukemia virus (BLV) is a retrovirus closely related to the human T-lymphotropic virus type 1 (HTLV-1). BLV is a major animal health problem worldwide causing important economic losses.
Lucas Vagnoni, Fanny Boulanger, Gerónimo Gutiérrez, Karina Trono, Irene Alvarez, Mathieu Boxus, María Teresa Sánchez-Alcaraz, Nicolas Gillet, Alix De Brogniez, Arnaud Florins, Sabrina M. Rodríguez, Luc Willems   +11 more
doaj   +1 more source

CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang, Qianqian Wang, Jiaming Zhang, Bingyu Li, Yuke Li, Zhengbo Chen, Dandan Guo, Shuying Feng   +7 more
wiley   +1 more source

Mapping of CD4+ T-cell epitopes in bovine leukemia virus from five cattle with differential susceptibilities to bovine leukemia virus disease progression

Virology Journal, 2019
Background Bovine leukemia virus (BLV), which is closely related to human T-cell leukemia virus, is the etiological agent of enzootic bovine leukosis, a disease characterized by a highly prolonged course involving persistent lymphocytosis and B-cell ...
Lanlan Bai, Shin-nosuke Takeshima, Masaaki Sato, William C. Davis, Satoshi Wada, Junko Kohara, Yoko Aida   +6 more
doaj   +1 more source

BLV-CoCoMo-qPCR: a useful tool for evaluating bovine leukemia virus infection status [PDF]

BMC Veterinary Research, 2012
AbstractBackgroundBovine leukemia virus (BLV) is associated with enzootic bovine leukosis, which is the most common neoplastic disease of cattle. BLV infects cattle worldwide, imposing a severe economic impact on the dairy cattle industry. Recently, we developed a new quantitative real-time polymerase chain reaction (PCR) method using Coordination of ...
Jimba Mayuko, Takeshima Shin-nosuke, Murakami Hironobu, Kohara Junko, Kobayashi Naohiko, Matsuhashi Tamako, Ohmori Takashi, Nunoya Tetsuo, Aida Yoko   +8 more
openaire   +3 more sources

The microbiome in cancer

iMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin, Minying Xiong, Aimin Jiang, Lihaoyun Huang, Hank Z. H. Wong, Suyin Feng, Chunyan Zhang, Yu Li, Li Chen, Hao Chi, Pengpeng Zhang, Bicheng Ye, Hengguo Zhang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Junyi Shen, Kailai Li, Wentao Xu, Haoxuan Ying, Cangang Zhang, Dongqiang Zeng, Jindong Xie, Xinpei Deng, Qi Wang, Jianying Xu, Wenjie Shi, Chang Qi, Chunrun Qu, Xufeng Huang, András Hajdu, Chaoqun Li, Changmin Peng, Xuanye Cao, Guangsheng Pei, Lin Zhang, Yujia Huo, Jiabao Xu, Antonino Glaviano, Attila Gábor Szöllősi, Sicheng Bian, Zhengrui Li, Hailin Tang, Bufu Tang, Zaoqu Liu, Jian Zhang, Kai Miao, Quan Cheng, Ting Wei, Shuofeng Yuan, Peng Luo   +50 more
wiley   +1 more source

Iron and ferritin levels in the serum and milk of bovine leukemia virus-infected dairy cows

Frontiers in Veterinary Science, 2015
Iron metabolism was examined in 15 bovine leukemia virus (BLV) -infected dairy cows (2.6-7.8 years old). BLV infection was detected by measuring serum antibody titer against BLV virus antigen (gp51).
KOICHI eORINO
doaj   +1 more source