Results 251 to 260 of about 281,340 (311)

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Assessment of bovine milk exosome preparation and lyophilized powder stability. [PDF]

J Extracell Biol
Lu L, Han C, Wang M, Du H, Chen N, Gao M, Wang N, Qi D, Bai W, Yin J, Dong F, Li T, Ge X.   +12 more
europepmc   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Evaluation of the reproducibility and performance characteristics of the Phagomagnetic separation-qPCR assay for rapidly detecting viable <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> in bovine milk and feces. [PDF]

Front Vet Sci
Grant IR, Sevilla IA, Molina E, Romero Martinez B, Lorente-Leal V, Thibault-Poisson VC, Cechova M, Köhler H.   +7 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Looking Inside of the Intestinal Permeability Regulation by Protein-Derivatives from Bovine Milk. [PDF]

Mol Nutr Food Res
Guzmán-Mejía F, Molotla-Torres DE, Godínez-Victoria M, Valdes-Hilarios X, Sánchez-Miranda E, Oros-Pantoja R, Drago-Serrano ME.   +6 more
europepmc   +1 more source

Bovine Milk Extracellular Vesicles as a Preventive Treatment for Bone Dysfunction and Metabolic Alterations in Obese Mice Fed a High-Refined Carbohydrate Diet. [PDF]

Mol Nutr Food Res
Silva FRF, Heredia JE, Arntz OJ, Barrioni BR, Teixeira MM, Silva TA, van de Loo FAJ, Macari S, Ferreira AVM, Oliveira MC.   +9 more
europepmc   +1 more source

The characterization of Lactobacillus strains in camel and bovine milk during fermentation: A comparison study. [PDF]

Heliyon
Alhaj OA, Jrad Z, Oussaief O, Jahrami HA, Ahmad L, Alshuniaber MA, Mehta BM.   +6 more
europepmc   +1 more source

Bovine milk extracellular vesicles prepared by ultracentrifugation contain microbial mRNAs that do not accumulate in human plasma following milk consumption. [PDF]

Extracell Vesicles Circ Nucl Acids
Mumtaz PT, Upadhyaya B, Shu J, Cui J, Zempleni J.   +4 more
europepmc   +1 more source

Single-Cell Analysis of Host Responses in Bovine Milk Somatic Cells (bMSCs) Following HPAIV Bovine H5N1 Influenza Exposure. [PDF]

Viruses
Singh G, Kafle S, Assato P, Goraya M, Morozov I, Richt JA.   +5 more
europepmc   +1 more source