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Human infection by a bovine strain of parainfluenza virus type 3
Journal of Medical Virology, 1980AbstractEtiological relationship between a bovine strain of parainfluenza virus type 3 and pneumonia in a child is suggested. Haemagglutination inhibition tests have clearly demonstrated that specific antibodies against the bovine virus were present in the patient's serum. The significance of this finding in relation to human infection is discussed.
A Avram, S Yatziv
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Molecular characterization of a Korean bovine parainfluenza virus type 3 isolate
Veterinary Microbiology, 2013Bovine parainfluenza virus type 3 (BPIV-3) was isolated from Korean native cattle that presented clinical signs of mild pneumonia. The complete genome of a representative isolate (12Q061) was sequenced. The newly identified strain, which was found to be distinct from the previously reported genotypes A (BPIV-3a) and B (BPIV-3b) and closely related to ...
Jae-Ku Oem +2 more
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Cytotoxic interactions between bovine parainfluenza type 3 virus and bovine alveolar macrophages
Veterinary Immunology and Immunopathology, 1999This paper describes an investigation of the cytotoxic activity of bovine alveolar macrophages for parainfluenza type 3 (PI-3) virus-infected target cells, using 51Cr release assays. Alveolar macrophages from uninfected calves were shown to be capable of killing PI-3 virus infected cells without the presence of antibody or complement (antibody ...
M S Mcnulty, J C Foster
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Effects of 4-Ipomeanol on Bovine Parainfluenza Type 3 Virus-induced Pneumonia in Calves
Veterinary Pathology, 1991Previous research has demonstrated that 4-ipomeanol toxicosis can enhance the severity of parainfluenza virus-induced pneumonia in mice. The objectives of this study were to determine whether calves are susceptible to 4-ipomeanol-induced enhancement of parainfluenza type 3 viral pneumonia and to determine whether 4-ipomeanol alters pulmonary ...
W L Castleman
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Veterinary Microbiology
Bovine Parainfluenza Virus Type 3 (BPIV3) serves as a crucial pathogen in cattle, adept at triggering severe respiratory symptoms. This investigation explores the intricate interplay of endoplasmic reticulum stress (ER stress), unfolded protein response (UPR), and autophagy upon BPIV3 infection.
Yu, Han +13 more
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Bovine Parainfluenza Virus Type 3 (BPIV3) serves as a crucial pathogen in cattle, adept at triggering severe respiratory symptoms. This investigation explores the intricate interplay of endoplasmic reticulum stress (ER stress), unfolded protein response (UPR), and autophagy upon BPIV3 infection.
Yu, Han +13 more
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Generation of a photocontrollable recombinant bovine parainfluenza virus type 3
Microbiology and Immunology, 2023AbstractBovine parainfluenza virus type 3 (BPIV3) is a promising vaccine vector against various respiratory virus infections, including the human PIV3, respiratory syncytial virus, and severe acute respiratory syndrome‐coronavirus 2 infections. In this study, we combined the Magnet system and reverse genetic approach to generate photocontrollable BPIV3.
Takashi Okura +5 more
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Cytotoxicity of bovine leucocytes for parainfluenza type-3 virus-infected cells
Veterinary Immunology and Immunopathology, 1992The cytotoxic effect of bovine neutrophils, alveolar macrophages, monocytes and lymphocytes for parainfluenza type-3 (PI-3) virus-infected cells in 51chromium-release assays is described. Specific lysis of virus-infected target cells with PI-3 virus antibody and complement was first observed 8 h after infection coincident with the appearance of ...
H E, Bradford +3 more
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In vitro stimulation of bovine circulating lymphocytes by parainfluenza type 3 virus
Research in Veterinary Science, 1977Bovine circulating lymphocytes from animals sero-positive to parainfluenza-3 virus (PIV-3) could be stimulated by PIV-3 antigen in a microculture system. A semiautomatic multiple sample harvester was used to collect the lymphocytes from the microplates. Ultraviolet-killed PIV-3 induced better stimulation values than formalin or heat-treated virus.
K, Johnson, B, Morein
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Journal of Infectious Diseases, 1988
Bovine parainfluenza virus type 3 (PIV-3) was evaluated as a candidate live-virus vaccine to protect against infection with human PIV-3. The level of replication of bovine and human PIV-3 and the efficacy of immunization with bovine PIV-3 in protecting against subsequent challenge with human PIV-3 was evaluated in nonhuman primates.
K L, van Wyke Coelingh +4 more
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Bovine parainfluenza virus type 3 (PIV-3) was evaluated as a candidate live-virus vaccine to protect against infection with human PIV-3. The level of replication of bovine and human PIV-3 and the efficacy of immunization with bovine PIV-3 in protecting against subsequent challenge with human PIV-3 was evaluated in nonhuman primates.
K L, van Wyke Coelingh +4 more
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Veterinary Microbiology, 1984
Six serum samples were taken at monthly intervals from birth to weaning from each of 41 newborn calves in the autumn and spring calf crops of a beef cow--calf herd. The serum hemagglutination-inhibition (HI) antibody titres to parainfluenza type 3 virus (PIV-3), virus-neutralization (VN) antibody titres to bovine adenovirus type 3 (BAV-3) and bovine ...
D W, Key, J B, Derbyshire
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Six serum samples were taken at monthly intervals from birth to weaning from each of 41 newborn calves in the autumn and spring calf crops of a beef cow--calf herd. The serum hemagglutination-inhibition (HI) antibody titres to parainfluenza type 3 virus (PIV-3), virus-neutralization (VN) antibody titres to bovine adenovirus type 3 (BAV-3) and bovine ...
D W, Key, J B, Derbyshire
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