Results 131 to 140 of about 5,713,232 (301)

Pharmacokinetics of pradofloxacin, florfenicol, and tulathromycin and response to treatment of steers experimentally infected with Mannheimia hemolytica

Journal of Veterinary Internal Medicine
Background Bovine respiratory disease (BRD) is an economically important disease in the beef industry, and a major driver of therapeutic antibiotic use. Pharmacokinetic data of these drugs is relatively limited in diseased animals.
Derek M. Foster, Jennifer L. Halleran, Megan E. Jacob, Stephanie Hempstead, Luke B. Borst, Tatiane T. Negrao Watanabe, Hiroko Enomoto, Mark G. Papich   +7 more
doaj   +1 more source

Influence of autolyzed yeast on the health of immunologically immature calves

Semina: Ciências Agrárias
Autolyzed yeast is a supplement option for calves due to its ability to stimulate the immune system and performance; however, there are few studies about the effect of different yeast derivatives.
Katlin Zamarchi Primel, Ana Carolina Araujo Abreu, Bianca Milla, Sarah Naiverth Oliveira, Karoline Vintureli Feliciano, Meire Christina Seki, Heloisa Godoi Bertagnon   +6 more
doaj   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Antimicrobial resistance in bovine respiratory disease: Auction market and ranch raised calves

, 2019
Antimicrobials are important tools in modern beef production. Antimicrobial drugs are often used for metaphylaxis to prevent and treat early cases of bovine respiratory disease complex (BRD) as well as for therapeutic purposes in feedlot cattle ...
Waldner, Cheryl L., Larson, Kathy, Campbell, John R., Trokhymchuk, Anatoliy, Windeyer, Claire, Wennekamp, Trent R.   +5 more
core   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Molecular Characterization of Pasteurella multocida Isolates From Fatal Cases of Bovine Respiratory Disease

, 2008
Bovine respiratory disease (BRD) is the most costly disease of beef cattle in North America. Mannheimia haemolytica is the most common cause of BRD, but recent work suggests that Pasteurella multocida is increasing in importance. Because P multocida is a
Confer, A. W., Lehenbauer, T. W., Dabo, S. M., Taylor, J. D., Fulton, R. W.   +4 more
core   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

Investigation of Bovine Respiratory Disease Pathogens using Immunohistochemistry Testing on Selected Samples

, 2005
During the fall of 2004, fall-placed feedlot calves that were diagnosed on gross postmortem examination with bovine respiratory disease (BRD) as the predominant cause of death were pathologically examined in detail using laboratory support to determine ...
Booker, C. W., Morley, P. S., Janzen, E. D., Phil, M., Guichon, P. T., Haines, D., Jim, G. K., Wildman, B. K., Felton, R. K., Clark, T. G., Perrett, T., Pittman, T. J., Schunicht, O. C.   +12 more
core   +1 more source

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Advanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang, Moon Sup Yoon, Jae Min Lee, Min Jeong Jo, Chae Eun Jin, Dae Hwan Shin   +5 more
wiley   +1 more source

Predicting bovine respiratory disease risk in feedlot cattle in the first 45 days post arrival

, 2021
Bovine respiratory disease (BRD) is the leading cause of morbidity and mortality in feedlot cattle. Improved predictions of BRD magnitude facilitates appropriate and judicious intervention application.
White, B.J., Rojas, Hector A., Armine, D.E., lARSON, r.l.   +3 more
core