Results 71 to 80 of about 2,196,624 (315)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Twenty-Eighth Annual Conference of the American Association of Bovine Practitioners: San Antonio, Texas, September 14-17, 1995

open access: yes, 1995
Description of the the Annual Conference of the American Association of Bovine Practitioners (28th : 1995), officers, district news, events, awards, and other ...
American Association of Bovine Practitioners,
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Twenty-Seventh Annual Conference of the American Association of Bovine Practitioners: Pittsburgh, Pennsylvania, September 22-25, 1994

open access: yes, 1994
Description of the the Annual Conference of the American Association of Bovine Practitioners (27th : 1994), officers, district news, events, awards, and other ...
American Association of Bovine Practitioners,
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Serum antibody response in calves receiving modified live and/or inactivated vaccines containing bovine herpesvirus-1, bovine viral diarrhea virus, parainfluenza-3 virus, and bovine respiratory syncytial virus immunogens

open access: yes, 1997
Serum antibody responses to bovine herpesvirus-1 (BHV-1) bovine viral diarrhea virus (BVDV), parainfluenza-3 virus (PI-3V), and bovine respiratory syncytial virus (BRSV) by calves receiving viral vaccines were evaluated.
Burge, Lurinda J.   +3 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

AABP Conference (2007): Minutes of the American Association of Bovine Practitioners: Business Luncheon, 22 September 2007, Pan Pacific Convention Center, Vancouver, British Columbia, Canada

open access: yes, 2008
Description of the 2007 American Association of Bovine Practitioners ...
Bovine Practitioners, American Association of
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Twenty-Sixth Annual Conference of the American Association of Bovine Practitioners: Albuquerque, New Mexico, September 16-19, 1993

open access: yes, 2019
Pre-conference program and description of the 26th Conference of the American Association of Bovine Practitioners, 1993 ...
Bovine Practitioners, American Association of
core   +1 more source

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