A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source
Characterization of the Soluble Nanoparticles Formed through Coulombic Interaction of Bovine Serum Albumin with Anionic Graft Copolymers at Low pH [PDF]
A static light scattering (SLS) study of bovine serum albumin (BSA) mixtures with two anionic graft copolymers of poly (sodium acrylate-co-sodium 2-acrylamido-2-methyl-1-propanesulphonate)-graft-poly (N, N-dimethylacrylamide), with a high composition in poly (N, N-dimethylacrylamide) (PDMAM) side chains, revealed the formation of oppositely charged ...
arxiv +1 more source
Binding of photosensitizing dyes with some biopolymers [PDF]
To obtain some information of the biological action of Kankohso 101dinicotinate and Kankohso 301-nicotinate, observations were made on the binding mode of these substances with protein, chondroitin sulfate and nucleic acids and the following results were
Yasui, Shigeo
core +1 more source
Protein adsorption on heterogeneous surfaces [PDF]
The adsorption of the protein bovine serum albumin from an aqueous solution onto substrata made from pure silica, pure zirconia, and a mixture of the two has revealed that the adsorption behavior of the protein onto the mixture very significantly ...
Aggarwal, Nitesh+4 more
core +2 more sources
BackgroundSerum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody fragments ...
Ralph Adams+18 more
doaj +1 more source
Quantitative studies on the interaction of concanavalin A, the carbohydrate-binding protein of the jack bean, with model carbohydrate-protein conjugates [PDF]
The interaction of concanavalin A with a comprehensive series of carbohydrate-bovine serum albumin comjugates was investigated by agar gel diffusion and quantitative precipitation techniques.
Agrawal+56 more
core +1 more source
Synthetic tumor-associated glycopeptide antigens. [PDF]
Glycopeptides with TN antigen (GalNAc)Ser/Thr and T-antigen structures (beta Gall-3GalNAc)Ser/Thr, described as tumor-associated antigens, were synthesized and coupled to bovine serum albumin. Alternatively, synthetic methods for the construction of beta-
Birnbach, S+7 more
core +2 more sources
Statistical Image Analysis of Drying Bovine Serum Albumin Droplets in Phosphate Buffered Saline [PDF]
A bio-colloidal drying droplet can be used as a pre-diagnostic technique. However, a successful clinical setting requires a fundamental understanding of the final morphology and the way it is related to the initial state of the constituents present in the droplet.
arxiv
Slow and remanent electric polarization of adsorbed BSA layer evidenced by neutron reflection [PDF]
Using neutron reflectivity together with an appropriate electrochemical cell, we have studied the effects of transverse electric field on the Bovine Serum Albumin (BSA) monolayer initially adsorbed at the interface of the aqueous solution and a conductive doped-silicon wafer. Depending on the sign of the initial potential, a second layer is adsorbed on
arxiv +1 more source
The present work is devoted to the synthesis and analysis of the physicochemical properties of new functionalized asymmetric Gemini surfactants. Herein, alkyl- and azide-substituted surfactants with symmetric and asymmetric substituents were synthesized ...
Ilshat Bogdanov+5 more
doaj +1 more source