Results 31 to 40 of about 731,960 (357)
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani +4 more
doaj +1 more source
A large potentiation effect of serum on the in vitro potency of tulathromycin against Mannheimia haemolytica and Pasteurella multocida [PDF]
The antimicrobial properties of tulathromycin were investigated for M.haemolytica and P.multocida. Three invitro indices of antimicrobial activity, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and time-kill curves ...
Alexander +33 more
core +3 more sources
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani +4 more
doaj +1 more source
Cell patterning on photolithographically defined parylene-C:SiO2 substrates [PDF]
Cell patterning platforms support broad research goals, such as construction of predefined in vitro neuronal networks and the exploration of certain central aspects of cellular physiology.
Brennan, Paul M +4 more
core +2 more sources
ATP binding to bovine serum albumin
Specific binding or ATP to bovine serum albumin (BSA) is demonstrated employing ATP derivatives spin‐labeled at either N6 or C8 of adenine ring or at the ribose moiety. Based on a 1:1 stoichiometry binding constants are in the 50–100 μM range. Binding is largely competitive with ATP or stearic acid. A small fraction of the labeled nucleotides could not
Bauer, Michael +2 more
openaire +2 more sources
Toward an Alternative Intrinsic Probe for Spectroscopic Characterization of a Protein [PDF]
The intrinsic fluorescent amino acid tryptophan is the unanimous choice for the spectroscopic investigation of proteins. However, several complicacies in the interpretation of tryptophan fluorescence in a protein are inevitable and an alternative ...
Goswami, Nirmal +2 more
core +1 more source
Adjuvant properties of polymer based on acrylic acid [PDF]
Adjuvant properties of the polymer containing acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established.
M. R. Kozak +3 more
doaj +1 more source
Anionic Calixarene-Capped Silver Nanoparticles Show Species-Dependent Binding to Serum Albumins
The anionic calixarenes para-sulphonatocalix[4]arene and 1,3-di-Ophosphonatocalix[ 4]arene, have been used to cap silver nanoparticles. The binding of these functional particles with regard to various serum albumins (bovine serum albumin, human serum ...
Anthony W. Coleman +4 more
doaj +1 more source
Diagnosis and Treatment of Infectious Enteritis in Adult Ruminants. [PDF]
Infectious enteritis in adult ruminants is often a result of 1 or more viral, bacterial, or parasitic pathogens. Diagnosis of etiologic agents causing enteritis is important when considering herd implications and zoonotic potential of some etiologies ...
Chigerwe, Munashe, Heller, Meera C
core +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source

