Results 31 to 40 of about 650,535 (339)

Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides

Frontiers in Immunology, 2023
BackgroundSerum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody fragments ...
Ralph Adams, Callum Joyce, Mikhail Kuravskiy, Katriona Harrison, Katriona Harrison, Zainab Ahdash, Matthew Balmforth, Kelda Chia, Cinzia Marceddu, Matthew Coates, James Snowden, Emmanuel Goursaud, Karelle Ménochet, Jean van den Elsen, Richard J. Payne, Richard J. Payne, Alastair D. G. Lawson, Anthony Scott-Tucker, Alex Macpherson   +18 more
doaj   +1 more source

ATP binding to bovine serum albumin

FEBS Letters, 1992
Specific binding or ATP to bovine serum albumin (BSA) is demonstrated employing ATP derivatives spin‐labeled at either N6 or C8 of adenine ring or at the ribose moiety. Based on a 1:1 stoichiometry binding constants are in the 50–100 μM range. Binding is largely competitive with ATP or stearic acid. A small fraction of the labeled nucleotides could not
Joachim Baumann, Wolfgang E. Trommer, Michael Bauer   +2 more
openaire   +2 more sources

Macromolecular sizes of serum albumins in its aqueous solutions

AIMS Biophysics, 2020
Changes in the structure and sizes of human and bovine serum albumins as well as polyvinyl alcohol macromolecules in aqueous solutions depending on temperature, concentration, and acid-base balance (pH) of the solutions are discussed.
Oleksii V. Khorolskyi, Nikolay P. Malomuzh   +1 more
doaj   +1 more source

Equilibrium Sorption of Structurally Diverse Organic Ions to Bovine Serum Albumin.

Environmental Science and Technology, 2016
Reliable partitioning data are essential for assessing the bioaccumulation potential and the toxicity of chemicals. In contrast to neutral organic chemicals, the partitioning behavior of ionogenic organic chemicals (IOCs) is still a black box for ...
Luise Henneberger, K. Goss, S. Endo
semanticscholar   +1 more source

New Asymmetric Gemini Triazole Surfactants with a Polar Triethylene Glycol Fragment: Synthesis and Physico-Chemical Properties

Molecules
The present work is devoted to the synthesis and analysis of the physicochemical properties of new functionalized asymmetric Gemini surfactants. Herein, alkyl- and azide-substituted surfactants with symmetric and asymmetric substituents were synthesized ...
Ilshat Bogdanov, Diana Mironova, Elza Sultanova, Vladimir Burilov, Svetlana Solovieva, Igor Antipin   +5 more
doaj   +1 more source

Bovine Serum Albumin Adsorption at a Silica Surface Explored by Simulation and Experiment.

Journal of Physical Chemistry B, 2017
Molecular details of BSA adsorption on a silica surface are revealed by fully atomistic molecular dynamics (MD) simulations (with a 0.5 μs trajectory), supported by dynamic light scattering (DLS), zeta potential, multiparametric surface plasmon resonance
Karina Kubiak-Ossowska, Karolina Tokarczyk, B. Jachimska, P. Mulheran   +3 more
semanticscholar   +1 more source

Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Chemistry Central Journal, 2017
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar   +4 more
doaj   +1 more source

FTIR study of secondary structure of bovine serum albumin and ovalbumin

, 2016
Proteins structure is the critical factor for their functioning. Fourier transform infrared spectroscopy provides a possibility to obtain information about secondary structure of proteins in different states and also in a whole biological samples ...
Karina V. Abrosimova, O. Shulenina, S. V. Paston   +2 more
semanticscholar   +1 more source

Anionic Calixarene-Capped Silver Nanoparticles Show Species-Dependent Binding to Serum Albumins

Molecules, 2013
The anionic calixarenes para-sulphonatocalix[4]arene and 1,3-di-Ophosphonatocalix[ 4]arene, have been used to cap silver nanoparticles. The binding of these functional particles with regard to various serum albumins (bovine serum albumin, human serum ...
Anthony W. Coleman, Florent Perret, Arnaud Brioude, Beomjoon Kim, Yannick Tauran   +4 more
doaj   +1 more source

Adjuvant properties of polymer based on acrylic acid [PDF]

The Ukrainian Biochemical Journal, 2013
Adjuvant properties of the polymer containing­ acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established.
M. R. Kozak, A. V. Oliynyk, O. S. Zaichenko, V. V. Vlizlo   +3 more
doaj   +1 more source