Results 11 to 20 of about 471,697 (267)

Glutaraldehyde-Polymerized Hemoglobin: In Search of Improved Performance as Oxygen Carrier in Hemorrhage Models

Bioinorganic Chemistry and Applications, 2020
Hemoglobin- (Hb-) based oxygen carriers (HBOC) have for several decades been explored for treatment of hemorrhage. In our previous top-up tests, HBOC with lower in vitro prooxidant reactivity (incorporating a peroxidase or serum albumin to this end ...
Anca D. Farcas, Vlad Al Toma, Ioana Roman, Bogdan Sevastre, Florina Scurtu, Radu Silaghi-Dumitrescu   +5 more
doaj   +1 more source

The Aminopropylation of Bovine Serum Albumin [PDF]

Australian Journal of Biological Sciences, 1967
After the reaction of reduced BSAt with BPA at pH 10·6 and subsequent hydrolysis of the protein with 6N HCl, only 40% of the lysine present in the unmodified protein can be accounted for on chromatographic analysis of the hydrolysate; a similar loss is observed of the SAPC into which the original cystine, which has totally disappeared, is presumably ...
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TALEN-mediated modification of the bovine genome for large-scale production of human serum albumin.

PLoS ONE, 2014
As an initial step towards creating genetically modified cattle as a biopharming source of recombinant human serum albumin (rHSA), we report modification of the bovine albumin (bA) locus by transcription activator-like effector nuclease (TALEN ...
Shaida Moghaddassi, Will Eyestone, Colin E Bishop   +2 more
doaj   +1 more source

Thermal coagulation of bovine serum albumin. [PDF]

Agricultural and Biological Chemistry, 1981
The effects of salts were investigated on thermo-coagulation of bovine serum albumin (BSA). Salts affected the formation of coagulum, and a “minimum” (a col) on the turbidity-pH curve was observed at about pH 7.5. When the time course of turbidity was measured at more acidic pH (6.5) or alkaline pH (9.5), an induction period was observed at the more ...
SHIMADA, Kazuko, MATSUSHITA, Setsuro
openaire   +2 more sources

Investigation of the interaction between indigotin and two serum albumins by spectroscopic approaches

Journal of Pharmaceutical Analysis, 2013
The binding characteristics of indigotin with human serum albumin (HSA) and bovine serum albumin (BSA) have been investigated by various spectroscopic techniques.
Zheng-Jun Cheng, Hong-Mei Zhao, Qian-Yong Xu, Rong Liu   +3 more
doaj   +1 more source

Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides

Frontiers in Immunology, 2023
BackgroundSerum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody fragments ...
Ralph Adams, Callum Joyce, Mikhail Kuravskiy, Katriona Harrison, Katriona Harrison, Zainab Ahdash, Matthew Balmforth, Kelda Chia, Cinzia Marceddu, Matthew Coates, James Snowden, Emmanuel Goursaud, Karelle Ménochet, Jean van den Elsen, Richard J. Payne, Richard J. Payne, Alastair D. G. Lawson, Anthony Scott-Tucker, Alex Macpherson   +18 more
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Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Chemistry Central Journal, 2017
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar   +4 more
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New Asymmetric Gemini Triazole Surfactants with a Polar Triethylene Glycol Fragment: Synthesis and Physico-Chemical Properties

Molecules
The present work is devoted to the synthesis and analysis of the physicochemical properties of new functionalized asymmetric Gemini surfactants. Herein, alkyl- and azide-substituted surfactants with symmetric and asymmetric substituents were synthesized ...
Ilshat Bogdanov, Diana Mironova, Elza Sultanova, Vladimir Burilov, Svetlana Solovieva, Igor Antipin   +5 more
doaj   +1 more source

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Frontiers in Chemistry, 2018
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani, Ahmed H. Bakheit, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar   +4 more
doaj   +1 more source

Adjuvant properties of polymer based on acrylic acid [PDF]

The Ukrainian Biochemical Journal, 2013
Adjuvant properties of the polymer containing­ acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established.
M. R. Kozak, A. V. Oliynyk, O. S. Zaichenko, V. V. Vlizlo   +3 more
doaj   +1 more source