Results 31 to 40 of about 1,184,647 (254)

Investigation of the interaction between indigotin and two serum albumins by spectroscopic approaches

Journal of Pharmaceutical Analysis, 2013
The binding characteristics of indigotin with human serum albumin (HSA) and bovine serum albumin (BSA) have been investigated by various spectroscopic techniques.
Zheng-Jun Cheng, Hong-Mei Zhao, Qian-Yong Xu, Rong Liu   +3 more
doaj   +1 more source

Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides

Frontiers in Immunology, 2023
BackgroundSerum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody fragments ...
Ralph Adams, Callum Joyce, Mikhail Kuravskiy, Katriona Harrison, Katriona Harrison, Zainab Ahdash, Matthew Balmforth, Kelda Chia, Cinzia Marceddu, Matthew Coates, James Snowden, Emmanuel Goursaud, Karelle Ménochet, Jean van den Elsen, Richard J. Payne, Richard J. Payne, Alastair D. G. Lawson, Anthony Scott-Tucker, Alex Macpherson   +18 more
doaj   +1 more source

An albumin-derived peptide scaffold capable of binding and catalysis [PDF]

, 2012
We have identified a 101-amino-acid polypeptide derived from the sequence surrounding the IIA binding site of human albumin. The polypeptide contains residues that make contact with ligands as warfarin in the parent protein, and eight cysteine residues ...
SBLATTERO, DANIELE, Fabio Benedetti, Giampaolo Fontanive (381542), SGARRA, RICCARDO, Daniele Sblattero (251886), Riccardo Sgarra (103906), Immacolata Luisi (381540), MAURIZIO, ELISA, Silvia Pavan (381541), Fabio Benedetti (243799), BENEDETTI, FABIO, Adriano Savoini, LUISI, Immacolata, Alessandro Tossi, Federico Berti, Immacolata Luisi, FONTANIVE, GIAMPAOLO, Silvia Pavan, Federico Berti (381545), BERTI, FEDERICO, Alessandro Tossi (381543), Elisa Maurizio, Ro Tossi, Adriano Savoini (381544), TOSSI, ALESSANDRO, Daniele Sblattero, Savoini A., PAVAN, SILVIA, Riccardo Sgarra, Elisa Maurizio (103901), Giampaolo Fontanive   +30 more
core   +2 more sources

Grafted block complex coacervate core micelles and their effect on protein adsorption on silica and polystyrene [PDF]

, 2010
peer reviewedWe have studied the formation and the stability of grafted block complex coacervate core micelles (C3Ms) in solution and the influence of grafted block C3M coatings on the adsorption of the proteins beta-lactoglobulin, bovine serum albumin ...
Arie de Keizer, Cohen Stuart, Martien A., Brzozowska, Agata M., Norde, Willem, Christophe Detrembleur, Detrembleur, Christophe, Cohen Stuart, M.A., Agata M. Brzozowska, Willem Norde, de Keizer, Arie, Keizer, A., de, Stuart, Martien Cohen, Norde, W., Brzozowska, A.M., Detrembleur, C., Martien A. Cohen Stuart, de Keizer, A.   +16 more
core   +2 more sources

Bovine Serum Albumin as A Superior “FP-Tag” for High-Throughput Glycosyltransferase Assay [PDF]

, 2020
Here, we report the development of a high-throughput “FP-Tag” OGT assay with bovine serum albumin as a low-cost and superior “FP-Tag”. With this assay, 2-methyleurotinone was identified as a low M-range OGT inhibitor.
Jiaxin, Li, Yuping, Wu, Senhua, Chen, Xinjian, Yin, Yue, Wang, Zhigang, She, Lan, Liu, Zhizeng, Gao   +7 more
core   +1 more source

Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Chemistry Central Journal, 2017
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar   +4 more
doaj   +1 more source

Inlet protein aggregation: a new mechanism for lubricating film formation with model synovial fluids. [PDF]

, 2011
This paper reports a fundamental study of lubricant film formation with model synovial fluid components (proteins) and bovine serum (BS). The objective was to investigate the role of proteins in the lubrication process.
Hart, A, R Underwood, C W Myant, Underwood, R, A Hart, P M Cann, Cann, PM, Fan, J, Myant, CW, J Fan   +9 more
core   +1 more source

New Asymmetric Gemini Triazole Surfactants with a Polar Triethylene Glycol Fragment: Synthesis and Physico-Chemical Properties

Molecules
The present work is devoted to the synthesis and analysis of the physicochemical properties of new functionalized asymmetric Gemini surfactants. Herein, alkyl- and azide-substituted surfactants with symmetric and asymmetric substituents were synthesized ...
Ilshat Bogdanov, Diana Mironova, Elza Sultanova, Vladimir Burilov, Svetlana Solovieva, Igor Antipin   +5 more
doaj   +1 more source

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Frontiers in Chemistry, 2018
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani, Ahmed H. Bakheit, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar   +4 more
doaj   +1 more source

Nasal Polyposis and Serum Albumin: Systemic Effects of Local Inflammation [PDF]

, 2023
Introduction The genesis of chronic rhinosinusitis is always a topic of debate. A polyp is a pale, edematous tissue emerging mostly from the middle meatus.
Sousa-Machado, André, Rosa, Francisco, Silva, Ana, Meireles, Luis   +3 more
core   +1 more source