Results 41 to 50 of about 650,535 (339)

Denaturation studies on bovine serum albumin–bile salt system: Bile salt stabilizes bovine serum albumin through hydrophobicity

open access: yesJournal of Pharmaceutical Analysis, 2018
Protein denaturation is under intensive research, since it leads to neurological disorders of severe consequences. Avoiding denaturation and stabilizing the proteins in their native state is of great importance, especially when proteins are used as drug ...
Karpagaraj Malarkani   +2 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Bovine thrombin enhances the efficiency and specificity of polymerase chain reaction

open access: yesBioTechniques, 2014
The polymerase chain reaction (PCR) has become one of the central techniques in molecular biology since its invention. However, PCR can be fraught with difficulties in various situations, and it is desirable to find novel PCR enhancers suitable for ...
Ying Zhang   +5 more
doaj   +1 more source

Probing the behavior and kinetic studies of amphiphilic acrylate copolymers with bovine serum albumin

open access: yesScientific Reports, 2023
This article presents that acrylate copolymers are the potential candidate against the adsorption of bovine serum albumin (BSA). A series of copolymers poly(methyl methacrylate) (pMMA), poly(3-sulfopropyl methacrylate-co-methyl methacrylate) p(SPMA-co ...
Shehla Mushtaq   +6 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Probing the secondary structure of bovine serum albumin during heat-induced denaturation using mid-infrared fiberoptic sensors.

open access: yesIn Analysis, 2015
Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy using a special waveguide based on a silver halide fiber was used for probing the heat-induced secondary structure and conformation changes of bovine serum albumin (BSA). From
R. Lu   +5 more
semanticscholar   +1 more source

THE SEROLOGICAL RELATIONSHIP OF BOVINE WHEY ALBUMIN TO SERUM ALBUMIN [PDF]

open access: yesJournal of Biological Chemistry, 1950
Serological reactions are becoming increasingly important in the development of quantitative methods for the determination and characterization of native proteins. These reactions provide a basis for analytical methods that combine high sensitivity with a high degree of specificity.
Henry Stevens, E. J. Coulson
openaire   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Effects of proteins on magnesium degradation - static vs. dynamic conditions

open access: yesJournal of Magnesium and Alloys, 2023
The interaction between organic molecules and biomaterial surfaces determines the fate of biomaterials during their service life, which is also the research hotspots in the field of biomaterials.
Ruiqing Hou   +4 more
doaj  

New Materials Based on Molecular Interaction between Hyaluronic Acid and Bovine Albumin

open access: yesMolecules, 2022
In this work, the interactions between hyaluronic acid and bovine serum albumin were investigated. The film-forming properties of the mixture were proven, and the mechanical and surface properties of the films were measured.
Magdalena Gadomska   +3 more
doaj   +1 more source

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