Results 41 to 50 of about 670,840 (353)
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani+4 more
doaj +1 more source
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani+4 more
doaj +1 more source
Macromolecular sizes of serum albumins in its aqueous solutions
Changes in the structure and sizes of human and bovine serum albumins as well as polyvinyl alcohol macromolecules in aqueous solutions depending on temperature, concentration, and acid-base balance (pH) of the solutions are discussed.
Oleksii V. Khorolskyi+1 more
doaj +1 more source
Adjuvant properties of polymer based on acrylic acid [PDF]
Adjuvant properties of the polymer containing acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established.
M. R. Kozak+3 more
doaj +1 more source
Effect of Langmuir monolayer of bovine serum albumin protein on the morphology of calcium carbonate [PDF]
Bovine serum albumin (BSA) Langmuir monolayer, as a model of biomineralization-associated proteins, was used to study its effect on regulated biomineralization of calcium carbonate. The effects of the BSA Langmuir monolayer and the concentration of the subphase solution on the nucleation and growth processes and morphology of the calcium carbonate ...
arxiv +1 more source
Anionic Calixarene-Capped Silver Nanoparticles Show Species-Dependent Binding to Serum Albumins
The anionic calixarenes para-sulphonatocalix[4]arene and 1,3-di-Ophosphonatocalix[ 4]arene, have been used to cap silver nanoparticles. The binding of these functional particles with regard to various serum albumins (bovine serum albumin, human serum ...
Anthony W. Coleman+4 more
doaj +1 more source
Effectivity of Insulin Transferrin Selenium and Bovine Serum Albumin Addition on In Vitro Culture Medium on Fertilization and Blastocyst Rate of Mice (Mus Musculus) [PDF]
The aim of this research was to know best composition of in vitro culture medium that can support the development of zygote and cleavage into blastocyst stage of embryo and ready to be transferred into recipient.
Luqman, Epy Muhammad+2 more
core
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Protein denaturation is under intensive research, since it leads to neurological disorders of severe consequences. Avoiding denaturation and stabilizing the proteins in their native state is of great importance, especially when proteins are used as drug ...
Karpagaraj Malarkani+2 more
doaj +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source