Results 71 to 80 of about 41,381 (279)

Automatic semantic segmentation for prediction of tuberculosis using lens-free microscopy images [PDF]

arXiv, 2020
Tuberculosis (TB), caused by a germ called Mycobacterium tuberculosis, is one of the most serious public health problems in Peru and the world. The development of this project seeks to facilitate and automate the diagnosis of tuberculosis by the MODS method and using lens-free microscopy, due they are easier to calibrate and easier to use (by untrained
arxiv  

Lessons learned and lingering uncertainties after seven years of chronic wasting disease management in Norway

Wildlife Biology, EarlyView.
Chronic wasting disease (CWD) is well known among cervids in North America. Nevertheless, management faced different types and degrees of uncertainty when CWD was first detected in reindeer Rangifer tarandus in Nordfjella, Norway in 2016. We present a timeline of the efforts to control CWD, and identify how the process, measurement, environmental, and ...
Atle Mysterud, Michael A. Tranulis, Olav Strand, Christer M. Rolandsen   +3 more
wiley   +1 more source

Resource‐driven changes in wild boar movement and their consequences for the spread of African Swine Fever in the Russian Far East

Wildlife Biology, EarlyView.
Knowledge of animal movement patterns is invaluable to understanding the spread of diseases among wildlife populations. One example is the recent African swine fever (ASF) outbreak among wild boar Sus scrofa populations across East Asia, where there is a lack of information on movements of this species.
Scott J. Waller, Kevin Morelle, Ivan V. Seryodkin, Alexander N. Rybin, Svetlana V. Soutyrina, Alain Licoppe, Mark Hebblewhite, Dale G. Miquelle   +7 more
wiley   +1 more source

Badgers as a potential source of bovine tuberculosis – first studies in Poland

Annals of Agricultural and Environmental Medicine, 2018
Since 2009, Poland has been recognized as a country officially free of bovine tuberculosis (BTB). However, new outbreaks are each year quoted. In many countries it has been shown that badgers ( Meles meles ) are a vector of Mycobacterium bovis/caprae (
Marek Lipiec, Krzysztof Nowakowski, Łukasz Radulski, Wojciech Iwaniak, Agnieszka Ważna   +4 more
doaj   +1 more source

Assessment of Spinster homologue 2 (Spns2)‐dependent transport of sphingosine‐1‐phosphate as a therapeutic target

British Journal of Pharmacology, Volume 182, Issue 9, Page 2014-2030, May 2025.
Abstract Background and Purpose Sphingosine‐1‐phosphate (S1P) receptor modulator (SRM) drugs suppress immune system function by disrupting lymphocyte trafficking, but SRMs are broadly immunosuppressive with on‐target liabilities. Another strategy to modulate the immune system is to block S1P transport.
Yugesh Kharel, Tao Huang, Kyle Dunnavant, Daniel Foster, George M. P. R. Souza, Katherine E. Nimchuk, Andrea R. Merchak, Caitlin M. Pavelec, Zuzanna J. Juskiewicz, Simon S. Alexander, Alban Gaultier, Stephen B. G. Abbott, Jung‐Bum Shin, Brant E. Isakson, Wehao Xu, Norbert Leitinger, Webster L. Santos, Kevin R. Lynch   +17 more
wiley   +1 more source

High‐throughput screening identifies bazedoxifene as a potential therapeutic for dysferlin‐deficient limb girdle muscular dystrophy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Limb‐girdle muscular dystrophy R2 (LGMD R2) is a rare genetic disorder characterised by progressive weakness and wasting of proximal muscles. LGMD R2 is caused by the loss of function of dysferlin, a transmembrane protein crucial for plasma membrane repair in skeletal muscles.
Celine Bruge, Nathalie Bourg, Emilie Pellier, Johana Tournois, Jerome Polentes, Manon Benabides, Noella Grossi, Anne Bigot, Anthony Brureau, Isabelle Richard, Xavier Nissan   +10 more
wiley   +1 more source

A case of bovine tuberculosis in pigs in Poland – a country free from the disease

Annals of Agricultural and Environmental Medicine, 2019
Introduction Bovine tuberculosis is a chronic contagious disease caused by Mycobacterium bovis or Mycobacterium caprae. Before widespread action conducted in Poland between 1959–1975 to combat bovine tuberculosis (BTB), about 40% of all tuberculosis ...
Marek Lipiec, Łukasz Radulski, Krzysztof Szulowski   +2 more
doaj   +1 more source

Interactions between chronic diseases: asymmetric outcomes of co-infection at individual and population scales [PDF]

arXiv, 2017
Co-infecting parasites and pathogens remain a leading challenge for global public health due to their consequences for individual-level infection risk and disease progression. However, a clear understanding of the population-level consequences of co-infection is lacking.
arxiv  

Depletion of Tregs from CD4+ CAR‐T cells enhances the tumoricidal effect of CD8+ CAR‐T cells in anti‐CD19 CAR‐T therapy

The FEBS Journal, Volume 292, Issue 8, Page 1904-1919, April 2025.
Chimeric antigen receptor T (CAR‐T) cell therapy represents a breakthrough in cancer immunotherapy. However, therapeutic resistance underscores the importance of investigating the impact of different CAR‐T cell subpopulations. Depletion of regulatory T cells (Tregs) from CD4+ CAR‐T cells enhances the anti‐tumor effects of CD8+ CAR‐T cells in CD19 ...
Yunyan Sun, Jinyan Liu, Dong Zhan, Jia Wei, Li XianShi, Rui Zhang, Ci Duan, Disi Zhang, Xiaorong Tang, Tuo Lin, Limei Li, Xun Lai   +11 more
wiley   +1 more source

Human and bovine tuberculosis knowledge, attitude and practice (KAP) among cattle owners in Ethiopia

Heliyon, 2021
Tuberculosis (TB) is a re-emerging disease occurring worldwide, resulting in multi-billion-dollar loss and human death annually. The situation is worse in developing countries like Ethiopia, where lower knowledge, attitude, and practice (KAP) of the ...
Amare Bihon, Solomon Zinabu, Yimer Muktar, Ayalew Assefa   +3 more
doaj