Results 81 to 90 of about 505,915 (296)
Advanced Science, EarlyView.To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai +4 more
wiley +1 more source
Advanced Science, EarlyView.Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo +11 more
wiley +1 more source
The Astronomical JournalMass-loss influences stellar evolution, especially for massive stars with strong winds. Stellar wind bow shock nebulae driven by Galactic OB stars can be used to measure mass-loss rates ( $\dot{M}$ ).
Angelica S. Whisnant +3 more
doaj +1 more source
Solar-Terrestrial Physics, 2020 Study of physical processes in plasma near planets often requires knowledge of the position and shape of the planetary bow shock. Empirical models are usually used since theoretical MHD and kinetic models consume too much computer time and cannot be used
G.A. Kotova +3 more
doaj +1 more source
The structure of perpendicular bow shocks
Journal of Geophysical Research: Space Physics, 1982 A hybrid simulation model with kinetic ions, massless fluid electrons, and phenomenological resistivity is used to study the perpendicular configuration of the bow shocks of the earth and other planets. We investigate a wide range of parameters, including the upstream Mach number, electron and ion beta (ratios of thermal to magnetic pressure), and ...
M. M. Leroy +4 more
openaire +1 more source
Advanced Science, EarlyView.Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami +7 more
wiley +1 more source
An Hα survey of infrared bow shocks around OB-type stars
Astronomy & AstrophysicsContext. Bow shocks around massive stars are commonly identified in mid-IR surveys, where emission from heated dust traces the interaction between stellar winds and the surrounding interstellar medium (ISM). In contrast, systematic optical investigations
Singh Saddal Kuljeet +5 more
doaj +1 more source
SAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source