Results 1 to 10 of about 32,873 (169)

Formulation and Systematic Optimisation of Polymeric Blend Nanoparticles via Box–Behnken Design [PDF]

Pharmaceutics
Background/Objectives: Despite the advantages of polycaprolactone (PCL) for drug delivery, it still lacks effective approaches to enhance its encapsulation of drugs.
Basant Salah Mahmoud, Christopher McConville   +1 more
doaj   +2 more sources

Box–Behnken design approach for optimizing the removal of non-steroidal anti-inflammatory drugs from environmental water samples using magnetic nanocomposite [PDF]

Scientific Reports
This study investigated the removal of naproxen (NAP) and diclofenac (DIC) from aqueous solutions using an Fe3O4/ZnO/GO magnetic composite. The effects of solution pH, ultrasonic irradiation time, FZG composite amount, and initial drug concentration were
Chuanyong Yan, Ying Zhang, Li Feng
doaj   +2 more sources

Optimizing blended cement concrete strength using the Box-Behnken design technique [PDF]

Scientific Reports
A properly optimized concrete mix design yields the required workability and strength for the fresh and hardened concrete to sustain desired loads and stresses over time, preventing premature failure. Thus, it is imperative to investigate the behavioural
Solomon Oyebisi, Mahaad Issa Shammas, Mohammed Seyam, Bonga Praisegod Khuzwayo   +3 more
doaj   +2 more sources

Optimization by Box–Behnken design for environmental contaminants removal using magnetic nanocomposite [PDF]

Scientific Reports
In this study, a CoO–Fe2O3/SiO2/TiO2 (CIST) nanocomposite was synthesized and utilized as an adsorbent to remove methylene blue (MB), malachite green (MG), and copper (Cu) from aqueous environments.
Luis Buenaño, Eyhab Ali, Ahmed Jafer, Shaima Haithem Zaki, Fathi Jihad Hammady, Salima Baqir Khayoun Alsaadi, Manal Morad Karim, Montather F. Ramadan, Alaa A. Omran, Ahmed Alawadi, Ali Alsalamy, Ali Kazemi   +11 more
doaj   +2 more sources

Bio-oil production from ripe pawpaw seeds and its optimal output: Box-Behnken Design and Machine Learning approach

Scientific African, 2023
The purpose of this study is to use ripe pawpaw seeds for a rapid Soxhlet extractor process with n-hexane to increase the yield of the bio-oil and to make the bio-oil produced a beneficial addition to the field of bio-oil production parameter ...
Sunday Chukwuka Iweka, F.C. Ozioko, E.D. Edafiadhe, T.F. Adepoju   +3 more
doaj   +1 more source

Preparation, Characterization, and Evaluation of Breviscapine Nanosuspension and Its Freeze-Dried Powder

Pharmaceutics, 2022
As a biopharmaceutics classification system (BCS) class IV drug, breviscapine (Bre) has low solubility in water, poor chemical stability, a short biological half-life and rapid removal from plasma.
Ting Zhang, Xixi Li, Juewen Xu, Jingbao Shao, Meihong Ding, Senlin Shi   +5 more
doaj   +1 more source

A comparison of two hybrid optimization techniques: the Taguchi-BBD-firefly and the Taguchi-regression-firefly methods on the IS 2062-E250 steel plates boring problem

Journal of Engineering and Applied Science, 2023
The expanding proliferation of components for engineering applications requires greater optimisation of parameters, which consequently increases the need for more efficient boring practices.
Ebun Fasina, Babatunde Alade Sawyerr, Yakubu Umar Abdullahi, Sunday Ayoola Oke   +3 more
doaj   +1 more source

Penerapan Desain Eksperimen Plackett-Burman dan Box-Behnken pada Analisis Voltametri Pulsa Diferensial untuk Penentuan Kadar Senyawa Kompleks Gd-DTPA

Alchemy, 2020
Gadolinium merupakan salah satu golongan unsur tanah jarang yang menarik karena memiliki sifat paramagnetik yang tinggi. Pengkhelatan gadolinium dengan ligan dietilentriaminpentaasetat (DTPA) menghasilkan senyawa yang berguna dalam bidang kesehatan ...
Santhy Wyantuti, Ravenna Aristantia, Yeni Wahyuni Hartati, Husein H Bahti   +3 more
doaj   +1 more source

Honokiol-Loaded Nanoemulsion for Glioblastoma Treatment: Statistical Optimization, Physicochemical Characterization, and an In Vitro Toxicity Assay

Pharmaceutics, 2023
Background: Glioblastoma (GBM) is an extremely invasive and heterogenous malignant brain tumor. Despite advances in current anticancer therapy, treatment options for glioblastoma remain limited, and tumor recurrence is inevitable.
Aleksandra Gostyńska, Joanna Czerniel, Joanna Kuźmińska, Jakub Brzozowski, Aleksandra Majchrzak-Celińska, Violetta Krajka-Kuźniak, Maciej Stawny   +6 more
doaj   +1 more source

Optimizing PHB and Protease Production by Box Behnken Design

International Islamic University Malaysia Engineering Journal, 2013
Mixed culture is more suitable to adapt more flexible fermentation process and produce different product simultaneously. In this study a mixed Bacillus culture was investigated for their ability to produce the bioplastic "Polyhydroxybutyrate" and both of
Amro Abd al fattah Amara
doaj   +1 more source