Results 41 to 50 of about 32,873 (169)

Optimization of the experimental parameters of fluticasone propionate microparticles for pulmonary delivery using a box behenken design

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
The objective of this study was to examine extensively the influences of formulation and process variables on the microparticles. The microparticles were generated by the spray-drying technique using polymer chitosan, mannitol along with L-leucine.
P V Patel   +3 more
doaj   +1 more source

Optimization Studies on Imatinib Mesylate Loaded Nanoliposomes Using Box-Behnken Design

open access: yesNano Biomedicine and Engineering, 2022
Nanoliposomes are bilayer phospholipid vesicles used to encapsulate and deliver therapeutic agents. The study was aimed to investigate the effects of critical variables on nanoliposomes characteristics.
Mandeep Dahiya   +12 more
doaj   +1 more source

Optimization of a Centrifugal Compressor Using the Design of Experiment Technique [PDF]

open access: yes, 2019
Centrifugal compressor performance is affected by many parameters, optimization of which can lead to superior designs. Recognizing the most important parameters affecting performance helps to reduce the optimization process cost.
Aungier, Mason, Mojaddam
core   +1 more source

Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]

open access: yes, 2015
A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A.   +3 more
core  

Designing pulse laser surface modification of H13 steel using response surface method [PDF]

open access: yes, 2011
This paper presents a design of experiment (DOE) for laser surface modification process of AISI H13 tool steel in achieving the maximum hardness and minimum surface roughness at a range of modified layer depth.
Aqida, S.N.   +2 more
core   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

open access: yesAdvanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed   +10 more
wiley   +1 more source

Multi-scale simulation of the nano-metric cutting process [PDF]

open access: yes, 2009
Molecular dynamics (MD) simulation and the finite element (FE) method are two popular numerical techniques for the simulation of machining processes. The two methods have their own strengths and limitations.
A Simoneau   +17 more
core   +1 more source

An Overview of Polyphenols and Color Chemistry in Cocoa

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Cocoa polyphenols have been traditionally known for their beneficial properties in human health. However, less is known about their other impacts on cocoa processing. This review highlights current discoveries in the role of polyphenols in the formation of color in cocoa.
Jasmeet Kaur Khanijou, Mario Wibowo
wiley   +1 more source

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

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