Results 71 to 80 of about 3,122,831 (248)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Development of High Voltage Electrical Box for CR300AF Fuxing EMUs

机车电传动, 2019
In order to protect the high-voltage electrical equipment on the roof of Fuxing EMUs from the influence of external harsh environment and ensure the good working performance of the equipment, the high-voltage electrical box on the roof of EMUs was ...
Yingyu YANG, Congjian JIANG, Tao LI, Xuejun HUANG   +3 more
doaj  

A highly nonlinear substitution-box (S-box) design using action of modular group on a projective line over a finite field.

PLoS ONE, 2020
Cryptography is commonly used to secure communication and data transmission over insecure networks through the use of cryptosystems. A cryptosystem is a set of cryptographic algorithms offering security facilities for maintaining more cover-ups.
Nasir Siddiqui, Fahim Yousaf, Fiza Murtaza, Muhammad Ehatisham-Ul-Haq, M Usman Ashraf, Ahmed M Alghamdi, Ahmed S Alfakeeh   +6 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Compressive strength differences between hybrid composites using post curing light box with LED and dry heating, in vitro

Padjadjaran Journal of Dentistry, 2011
A hybrid type of composite resins is used as dental restorative materials in a wide cavity directly or indirectly. The mechanical properties of the composite resin would increase post-curing.
Jenny Krisnawaty, Setiawan Natasasmita, Dudi Aripin   +2 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

STUDY ON PROBABILISTIC SAFETY ASSESSMENT FOR BOX GIRDER OF BRIDGE AND GANTRY CRANE

Jixie qiangdu, 2017
Considering the uncertainty of the load,the fracture toughness,the yield strength,the tensile strength,and based on the failure assessment diagram technique（ FAD）,as well as combining with the finite element analysis results of crane structure,the ...
LUO YouHong, WU Xiao, XIONG Gang, DING ZhengNan   +3 more
doaj  

Overall Buckling Behavior and Design of Steel Stiffened Box Section Columns Under Axial Compression

Buildings
This study experimentally and numerically investigated the overall buckling behavior of steel box column components. Two box section specimens were fabricated for axial compression tests.
Bing Shangguan, Jie Li, Qiu Zhao, Peng Chen, Furong Ruan, Huiteng Pei   +5 more
doaj   +1 more source