Results 51 to 60 of about 3,122,831 (248)
Revolutionizing Corrugated Board Production and Optimization with Artificial Intelligence
BioResourcesIn the field of corrugated board production and packaging optimization, the advent of Artificial Intelligence (AI) has initiated a paradigm shift. This paper presents a brief analysis of AI's role in revolutionizing both the production of corrugated ...
Tomasz Garbowski
doaj +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Residual stresses in high strength steel welded box sections
, 2016 Induced residual tensile and compressive stresses generated by the fabrication process can cause premature buckling and reduce the ultimate axial strength of welded steel box sections subjected to compressive loads.
Paradowska, Anna +4 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Experimental studies of scale effects on shear strength, and deformation of rock joints [PDF]
, 1980 The effect of scale on shear strength is studied by performing direct shear tests on different sized samples of large joints. A rubber moulding system is used to obtain impressions of the roughness from a variety of natural joint surfaces.
Bandis, Stavros
core +5 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Experimental and numerical investigation of the flexural behavior of CFRP box girders
Advanced Composites Letters, 2019 The advantages of carbon fiber-reinforced plastic (CFRP) box girders include good bending resistance, lightweight and high strength. Therefore, they are widely used in aerospace, rail transit, and other fields.
Guoping Ding, Yixuan Zhang, Yong Zhu
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Journal of Materials Research and Technology, 2019 This study presents the relationship between the rheology and the compressive strength of self-compacting concrete (SCC). The concrete mixes contained eight different dosages of superplasticizer.
M. Benaicha +3 more
doaj +1 more source