Results 71 to 80 of about 4,291 (203)

The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression [PDF]

Oncogene, 2019
BP180, also termed collagen XVII, is a hemidesmosomal transmembrane glycoprotein expressed in basal keratinocytes, and functions as a cell-matrix adhesion molecule in the dermal-epidermal junction of the skin. Its function, other than cell-matrix adhesion, remains unclear.
Bin-Jin Hwang, Yang Zhang, Jaime M. Brozowski, Zhen Liu, Susan Burette, Kendall Lough, Christof C. Smith, Yue Shan, Jinbo Chen, Ning Li, Scott Williams, Maureen Su, Paul Googe, Nancy E. Thomas, Zhi Liu   +14 more
openaire   +4 more sources

Incidence of P200 pemphigoid: A nationwide study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen, Marion Carrette, Marie‐Laure Golinski, Maud Maho‐Vaillant, Alexis Lefebvre, André Gillibert, Pascal Joly, Vivien Hébert   +7 more
wiley   +1 more source

Prevalence of Skin-specific Autoantibodies in HIV-infected Patients and Uninfected Controls

Acta Dermato-Venereologica, 2019
Various autoantibodies are detected more frequently in HIV-infected individuals than in HIV-negative controls; however, limited data exist regarding autoimmune blistering skin diseases.
Veronique Touzeau-Roemer, Michael Skoll, Pooja Tajpara, Philip Kienzl, Antonia Wesinger, Simona Saluzzo, Martin Bauer, Maximilian C. Aichelburg, Christine Bangert, Wolfgang Bauer, Georg Stingl, Armin Rieger, Katharina Grabmeier-Pfistershammer, Christopher Schuster   +13 more
doaj   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini, Gioele Gioco, Michele Davide Mignogna, Stefania Leuci, Francesco Scilla, Davide Gentile, Cosimo Rupe, Enrico Russo, Anna Schiavelli, Carlo Lajolo   +9 more
wiley   +1 more source

Bullous dermatoses secondary to anti-PD-L1 agents: a case report and review of the literature [PDF]

, 2019
Immune checkpoint inhibitors are used to treat numerous malignancies but may be associated with severe adverse events. Bullous dermatoses, chiefly bullous pemphigoid (BP), are potentially progressive adverse events that cause blistering skin lesions and ...
Choi, Jennifer N, Kosche, Cory, Owen, Joshua L, Sadowsky, Lauren M   +3 more
core  

Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 2, Page 186-198, April 2026.
Skin adverse events (AEs) frequently accompany all types of anticancer treatments. This publication discusses how recent international guidance on best‐practices use of dermocosmetics can be adapted to the North Asia region (China, Hong Kong, Japan, Republic of Korea, and Taiwan).
Meng Pan, Jianguo Sun, Makoto Kawashima, You Chan Kim, Mison Chun, Chia‐Yu Chu, Yi‐Hsin Liang, Mee Chang, Delphine Kerob, Brigitte Dreno   +9 more
wiley   +1 more source

Immunological and Statistical Studies of Anti-BP180 Antibodies in Paraneoplastic Pemphigus [PDF]

Journal of Investigative Dermatology, 2014
Abbreviations: BMZ, basement membrane zone; BP, bullous pemphigoid; HaCaT, concentrated culture supernatant of HaCaT cells; IB, immunoblotting; IF, immunofluorescence; PNP, paraneoplastic pemphigus; RP, recombinant ...
Tsuchisaka, Atsunari, Kawano, Hideo, Yasukochi, Atsushi, Teye, Kwesi, Ishii, Norito, Koga, Hiroshi, Sogame, Ryosuke, Ohzono, Ayaka, Krol, Rafal P., Kawakami, Tamihiro, Furumura, Minao, Ohata, Chika, Li, Xiaoguang, Hashimoto, Takashi   +13 more
openaire   +2 more sources

The Autoimmune Skin Disease Bullous Pemphigoid: The Role of Mast Cells in Autoantibody-Induced Tissue Injury

Frontiers in Immunology, 2018
Bullous pemphigoid (BP) is an autoimmune and inflammatory skin disease associated with subepidermal blistering and autoantibodies directed against the hemidesmosomal components BP180 and BP230. Animal models of BP were developed by passively transferring
Hui Fang, Yang Zhang, Yang Zhang, Ning Li, Gang Wang, Zhi Liu, Zhi Liu, Zhi Liu   +7 more
doaj   +1 more source

Bullous Pemphigoid and Cicatricial Pemphigoid Autoantibodies React with Ultrastructurally Separable Epitopes on the BP180 Ectodomain: Evidence that BP180 Spans the Lamina Lucida

Journal of Investigative Dermatology, 1997
The BP180 antigen is a hemidesmosomal glycoprotein that is recognized by autoantibodies associated with three autoimmune disorders, bullous pemphigoid (BP), herpes gestationis (HG), and cicatricial pemphigoid (CP). BP and HG sera have been shown to recognize a common extracellular site located near the membrane-spanning domain of this protein, whereas ...
Bédane, Christophe, McMillan, James R., Balding, Shawn D., Bernard, Philippe, Prost, Catherine, Bonnetblanc, Jean-Marie, Diaz, Luis A., Eady, Robin A.J., Giudice, George J.   +8 more
openaire   +2 more sources

Neutrophils in animal models of autoimmune disease [PDF]

, 2016
Neutrophils have traditionally been thought to play only a peripheral role in the genesis of many autoimmune and inflammatory diseases. However, recent studies in a variety of animal models suggest that these cells are central to the initiation and ...
Abram, Ajuebor, Albanesi, Alves, Amaral, Askenasy, Attila Mócsai, Aube, Baik, Barnado, Bento, Binstadt, Braswell, Brinkmann, Buanne, Campbell, Campbell, Carlson, Carneiro-Sampaio, Chan, Chen, Chen, Chen, Chiriac, Christensen, Clifford A. Lowell, Coit, Coquery, Cronstein, Croxford, Cumpelik, Diana, Diana, Ditzel, Dwivedi, Ehrenstein, Elliott, Eyles, Forster, Fournier, Futosi, Gaipl, Garcia, Goldberg, Grayson, Guerreiro-Cacais, Guiducci, Gupta, Hattar, Heimbach, Helms, Henry, Heymann, Hickman, Holden, Huang, Kahlenberg, Kallenberg, Kaplan, Katayama, Kelkka, Kessenbrock, Kim, Kishida, Knight, Knight, Knight, Kovacs, Kuhl, Lamagna, Lande, Li, Lin, Lindwall, Liu, Lood, Maalouf, Maicas, Mancardi, Marciano, Marrakchi, Martinon, Mayadas, McColl, McGonagle, McGonagle, Merrill, Metzler, Metzler, Miller, Milora, Mocsai, Mocsai, Moline-Velazquez, Nemeth, Nesterovitch, O'Shea, Odobasic, Odobasic, Okumura, Ooi, Oswald, Palanichamy, Palmen, Patel, Pfister, Pieterse, Pietronigro, Pietrosimone, Rodrigues-Sousa, Rohrbach, Rumble, Ryckman, Sadik, Samavedam, Sangaletti, Scapini, Scapini, Schauer, Schmidt, Schon, Schon, Schreiber, Schreiber, Schreiber, Shao, Smith, Smith, So, Spengler, Steiger, Steinbach, Sumida, Summers, Tamás Németh, Terkeltaub, Tortola, Ueyama, van der Fits, Vandal, Volmering, Wallace, Walter, Willis, Wipke, Wise, Xiao, Yu, Zehntner, Zenaro, Zhang, Zhang   +151 more
core   +2 more sources