Results 51 to 60 of about 3,264 (192)

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

180-kd bullous pemphigoid antigen (BP180) is deficient in generalized atrophic benign epidermolysis-bullosa [PDF]

, 1995
Generalized atrophic benign epidermolysis bullosa (GABEB) is a form of nonlethal junctional epidermolysis bullosa characterized by universal alopecia and atrophy of the skin.
M F Jonkman, J B van der Meer, Develasco, AMM, K Owaribe, Heeres, K, de Jong, MCJM, A M Martinez de Velasco, Jonkman, MF, Niessen, CM, A Sonnenberg, van der Meer, JB, H H Pas, Owaribe, K, K Heeres, Pas, HH, Sonnenberg, A, M C de Jong, C M Niessen   +17 more
core   +2 more sources

High Index Values of Enzyme-Linked Immunosorbent Assay for BP180 at Baseline Predict Relapse in Patients With Bullous Pemphigoid

Frontiers in Medicine, 2018
Bullous pemphigoid (BP) presenting with erythema plaques and tense blisters is the most frequent autoimmune bullous disease. Immunologically, BP is characterized by the presence of circulating anti-epidermal basement membrane zone (BMZ) antibodies.
Hiroshi Koga, Kwesi Teye, Norito Ishii, Chika Ohata, Takekuni Nakama   +4 more
doaj   +1 more source

Case Report: Bullous Pemphigoid Associated With Morphea and Lichen Sclerosus: Coincidental Diseases or Pathogenetic Association?

Frontiers in Immunology, 2022
Bullous pemphigoid (BP) represents the most common autoimmune bullous disease and is characterized by IgG autoantibodies targeting collagen XVII (BP180). BP has reportedly been occurred in association with other inflammatory skin diseases.
Roberto Maglie, Maria Efenesia Baffa, Francesca Montefusco, Carlo Pipitò, Stefano Senatore, Marco Capassoni, Marco Capassoni, Vincenza Maio, Marco Matucci Cerinic, Marco Matucci Cerinic, Emiliano Antiga, Serena Guiducci, Serena Guiducci   +12 more
doaj   +1 more source

Molecular genetic studies of a human epidermal autoantigen (the 180-kD bullous pemphigoid antigen/BP180): identification of functionally important sequences within the BP180 molecule and evidence for an interaction between BP180 and alpha 6 integrin. [PDF]

The Journal of cell biology, 1995
The 180-kD bullous pemphigoid autoantigen (BP180) is a component of the hemidesmosome, a cell-matrix connector. This protein is oriented in a type II fashion in the membrane of the hemidesmosome and is a hybrid collagen (classified as type XVII). We have analyzed the fate of various mutant BP180 molecules transfected into several different cell types ...
S B, Hopkinson, S E, Baker, J C, Jones
openaire   +2 more sources

Omalizumab as a corticosteroid‐sparing agent in the treatment of bullous pemphigoid

Dermatologic Therapy, 2022
Bullous pemphigoid (BP) is the most common autoimmune blistering skin disease, characterized by the development of autoantibodies against hemidesmosomal components BP180 and BP230.
Camilla Vassallo, Anita Somenzi, Mara De Amici, Stefania Barruscotti, Valeria Brazzelli   +4 more
doaj   +1 more source

Effect and length of doxycycline administration in elderly patients with bullous pemphigoid

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease and primarily affects the elderly. Systemic corticosteroids and immunosuppressive drugs are the standard treatment, but side effects often restrict their use. Doxycycline has been proposed as an alternative, but there is limited long‐term, real‐world data on its
Alena Merkel‐Ropele, Wolfgang Salmhofer, Peter Wolf   +2 more
wiley   +1 more source

Assessing Disease Outcome Measures in Bullous Pemphigoid on Standard-Of-Care Therapies

JID Innovations, 2021
Bullous pemphigoid (BP) is an autoimmune blistering disease resulting in pruritus and cutaneous blistering. Longitudinal studies characterizing the disease course of patients with BP on conventional therapy are lacking.
Emily F. Cole, Taryn DeGrazia, Yuxian Sun, Yuan Liu, Ron J. Feldman   +4 more
doaj   +1 more source

Relation between antibodies to BP180 and gender in bullous pemphigoid

Journal of the American Academy of Dermatology, 1999
Bullous pemphigoid is associated with antibodies to 2 basement membrane zone antigens (BP230 and BP180). In some patients antibodies develop to one of these antigens, whereas in others antibodies develop to both. Although the factors behind this are unknown, our study indicates that male gender is one factor.
D, Jiao, J C, Bystryn
openaire   +2 more sources

بررسی غلظت سرمی گلیکوپروتئین BP180 در بیماران مبتلا به مولتیپل اسکلروزیس و در گروه کنترل در بیمارستان الزهرا (س) [PDF]

مجله دانشکده پزشکی اصفهان
مقاله پژوهشی مقدمه: مولتیپل اسکلروزیس، یک بیماری خودایمنی است که در آن فرایند دمیلیناسیون رخ می‌دهد که منجر به اختلالات انتقال پیام عصبی می‌شود. پژوهشگران بین بیماری‌های عصبی و غلظت سرمی گلیکوپروتئین رابطه‌ی معنادار شناسایی کردند.
آذر برادران, محمد رضا سراج الدین   +1 more
doaj   +1 more source