Results 31 to 40 of about 2,229 (127)

Analysis of the autoimmune response against BP180 and BP230 in ethnic Poles with neurodegenerative disorders and bullous pemphigoid

Central European Journal of Immunology, 2017
Recent studies postulated the association between bullous pemphigoid (BP) and neurodegenerative disorders (ND). The autoantibodies to BP180 and/or BP230 may be present not only in BP, but also in ND as neuronal isoforms of these proteins are identified ...
Justyna Gornowicz-Porowska, Agnieszka Seraszek-Jaros, Monika Bowszyc-Dmochowska, Elżbieta Kaczmarek, Paweł Pietkiewicz, Paweł Bartkiewicz, Marian Dmochowski   +6 more
doaj   +1 more source

High Index Values of Enzyme-Linked Immunosorbent Assay for BP180 at Baseline Predict Relapse in Patients With Bullous Pemphigoid

Frontiers in Medicine, 2018
Bullous pemphigoid (BP) presenting with erythema plaques and tense blisters is the most frequent autoimmune bullous disease. Immunologically, BP is characterized by the presence of circulating anti-epidermal basement membrane zone (BMZ) antibodies.
Hiroshi Koga, Kwesi Teye, Norito Ishii, Chika Ohata, Takekuni Nakama   +4 more
doaj   +1 more source

Assessing Disease Outcome Measures in Bullous Pemphigoid on Standard-Of-Care Therapies

JID Innovations, 2021
Bullous pemphigoid (BP) is an autoimmune blistering disease resulting in pruritus and cutaneous blistering. Longitudinal studies characterizing the disease course of patients with BP on conventional therapy are lacking.
Emily F. Cole, Taryn DeGrazia, Yuxian Sun, Yuan Liu, Ron J. Feldman   +4 more
doaj   +1 more source

Bullous pemphigoid and mucous membrane pemphigoid humoral responses differ in reactivity towards BP180 midportion and BP230

Frontiers in Immunology
BackgroundBullous pemphigoid (BP) and mucous membrane pemphigoid (MMP) are rare autoimmune blistering disorders characterized by autoantibodies (autoAbs) targeting dermo-epidermal junction components such as BP180 and BP230.
Feliciana Mariotti, Anna Pira, Naomi De Luca, Anna Rita Giampetruzzi, Filomena Russo, Amilcare Cerri, Giulia Gasparini, Giulia Gasparini, Emanuele Cozzani, Emanuele Cozzani, Angelo V. Marzano, Angelo V. Marzano, Emiliano Antiga, Marzia Caproni, Pietro Quaglino, Marco Carrozzo, Biagio Didona, Giovanni Di Zenzo   +17 more
doaj   +1 more source

بررسی غلظت سرمی گلیکوپروتئین BP180 در بیماران مبتلا به مولتیپل اسکلروزیس و در گروه کنترل در بیمارستان الزهرا (س) [PDF]

مجله دانشکده پزشکی اصفهان
مقاله پژوهشی مقدمه: مولتیپل اسکلروزیس، یک بیماری خودایمنی است که در آن فرایند دمیلیناسیون رخ می‌دهد که منجر به اختلالات انتقال پیام عصبی می‌شود. پژوهشگران بین بیماری‌های عصبی و غلظت سرمی گلیکوپروتئین رابطه‌ی معنادار شناسایی کردند.
آذر برادران, محمد رضا سراج الدین   +1 more
doaj   +1 more source

Incidence of P200 pemphigoid: A nationwide study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen, Marion Carrette, Marie‐Laure Golinski, Maud Maho‐Vaillant, Alexis Lefebvre, André Gillibert, Pascal Joly, Vivien Hébert   +7 more
wiley   +1 more source

Checkpoint Inhibition May Trigger the Rare Variant of Anti-LAD-1 IgG-Positive, Anti-BP180 NC16A IgG-Negative Bullous Pemphigoid

Frontiers in Immunology, 2019
Bullous pemphigoid (BP) is an autoimmune blistering skin disease characterized by an autoimmune response to type XVII collagen (BP180). The generation of anti-BP180-NC16A IgG autoantibodies is considered to be central to the pathogenesis of BP, in part ...
Christian D. Sadik, Ewan A. Langan, Victoria Grätz, Detlef Zillikens, Patrick Terheyden   +4 more
doaj   +1 more source

Case report: Mucous membrane pemphigoid with complicated autoantibody profile indicating the necessity of comprehensive diagnostic methods and the contribution of IgA autoantibodies

Frontiers in Immunology, 2023
Mucous membrane pemphigoid (MMP) is a type of subepithelial autoimmune bullous disease, affecting various mucosae, occasionally with skin lesions. Both diagnosis and treatment of MMP are difficult.
Weijun Liu, Huicheng Li, Yun Jin, Yun Jin, Lifang Cheng, Luhuai Shi, Yangmin Gao, Zhijun Zhou, Suying Feng, Hua Qian, Takashi Hashimoto, Xiaoguang Li   +11 more
doaj   +1 more source

Tocilizumab for severe and refractory mucous membrane pemphigoid

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt, Maud Maho‐Vaillant, Julie Gueudry, Marie‐Laure Golinski, Marion Marcaillou, Blanche Bergeret, Guillaume Chambon, Pierre Bouchetemble, Soumeya Bekri, Abdellah Tebani, Hervé Maillard, Cécile Morice, Anais Vautier, Edgar‐Pierre Libert, Christelle Le Roux‐Villet, Marion Carrette, Olivier Boyer, Vivien Hébert, Sébastien Calbo, André Gillibert, Pascal Joly   +20 more
wiley   +1 more source

Elevated BP180 ELISA at Diagnosis Correlates with Disease Severity and Relapse in Oral Mucous Membrane Pemphigoid: Preliminary Results from a Retrospective Monocentric Italian Study

Applied Sciences
Background: Little is known about the relevance of BP180 ELISA for the clinical management of oral mucous membrane pemphigoid (OMMP). The aim of the present study was to investigate if the levels of anti-BP180 antibodies at diagnosis could be correlated ...
Andrea Gabusi, Davide B. Gissi, Roberto Rossi, Federica Filippi, Camilla Loi, Cosimo Misciali, Giacomo Clarizio, Michelangelo La Placa, Federico Bardazzi   +8 more
doaj   +1 more source