Results 11 to 20 of about 2,229 (127)

Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment [PDF]

Frontiers in Medicine
ObjectiveThis study aimed to explore the relationship between serum levels of interleukin-17 (IL-17), interleukin-18 (IL-18), interleukin-22 (IL-22), interleukin-25 (IL-25), anti-BP180 antibodies, anti-BP230 antibodies, and immunoglobulin E (IgE) and the
Xinyi Hong, Xinyi Hong, Xinyi Hong, Xinyi Hong, Xiuqin Wang, Xiuqin Wang, Xiuqin Wang, Xiuqin Wang, Yin Cheng, Yin Cheng, Yin Cheng, Yin Cheng, Hanqing Song, Hanqing Song, Hanqing Song, Hanqing Song, Congcong Xu, Congcong Xu, Congcong Xu, Congcong Xu, Peiguang Wang, Peiguang Wang, Peiguang Wang, Peiguang Wang   +23 more
doaj   +2 more sources

Evaluation of a novel chemiluminescent immunoassay for autoantibody detection in pemphigus and bullous pemphigoid [PDF]

Frontiers in Immunology
BackgroundA novel fully automated chemiluminescent immunoassay (CLIA) has been developed to quantify autoantibodies specific for desmogleins (Dsg1, Dsg3), BP180, and BP230, key target antigens in pemphigus and bullous pemphigoid.
Na Zhang, Ming Wang, Lili Hou, Yanyu Zhang, Yan Zhao, Luyang Du, Xiaoqing Li, Xia Liu, Hongwei Zhou, Jiaxuan Hao, Jing Tian, Qiuping Yu, Lixia Li, Fangming Cheng, Hai-Zhou Zhou   +14 more
doaj   +2 more sources

Analysis of the autoimmune response to BP180 in Chinese stroke patients [PDF]

Anais Brasileiros de Dermatologia, 2023
Background Significant association between bullous pemphigoid (BP) and stroke has been reported. This study aimed to evaluate the level of anti-BP180 antibody in stroke patients to explore the relationship between BP and stroke in their pathogenesis ...
Jing Wang, Hong Liu, Zhenzhen Wang, Qing Pan, Furen Zhang   +4 more
doaj   +1 more source

Current approaches to the diagnosis of autoimmune bullous dermatoses

Vestnik Dermatologii i Venerologii, 2021
A modern review of highly effective methods for the diagnosis of autoimmune bullous dermatoses are presented. The specificity of the production of autoantibodies underlying bullous dermatoses are described.
Marianna B. Drozhdina, Varvara A. Bobro, Yuliana A. Sennikova   +2 more
doaj   +1 more source

Foot-and-Mouth Disease Virus 3C^pro Cleaves BP180 to Induce Blister Formation

Viruses, 2022
Foot-and-mouth disease (FMD) is mainly characterized by blister formation (vesicles) in animals infected with foot-and-mouth disease virus (FMDV). However, the molecular basis of the blister formation in FMD is still unknown.
Pathum Ekanayaka, Asela Weerawardhana, Kiramage Chathuranga, Jong-Hyeon Park, Jong-Soo Lee   +4 more
doaj   +1 more source

Type XVII collagen: Relevance of distinct epitopes, complement-independent effects, and association with neurological disorders in pemphigoid disorders

Frontiers in Immunology, 2022
Pemphigoid diseases (PD) are autoimmune skin blistering diseases characterized by autoantibodies directed against proteins of the cutaneous basement membrane zone (BMZ).
Bianca Opelka, Enno Schmidt, Enno Schmidt, Stephanie Goletz   +3 more
doaj   +1 more source

Autoreactive Peripheral Blood T Helper Cell Responses in Bullous Pemphigoid and Elderly Patients With Pruritic Disorders

Frontiers in Immunology, 2021
Bullous pemphigoid (BP) is a prototypic autoimmune disorder of the elderly, characterized by serum IgG autoantibodies, namely anti-BP180 and anti-BP230, directed against components of the basal membrane zone that lead to sub-epidermal loss of adhesion ...
Dario Didona, Luca Scarsella, Milad Fehresti, Farzan Solimani, Farzan Solimani, Hazem A. Juratli, Manuel Göbel, Stefan Mühlenbein, Lily Holiangu, Josquin Pieper, Vera Korff, Thomas Schmidt, Cassian Sitaru, Rüdiger Eming, Michael Hertl, Robert Pollmann   +15 more
doaj   +1 more source

Rapid Disease Control in First-Line Therapy-Resistant Mucous Membrane Pemphigoid and Bullous Pemphigoid with Omalizumab as Add-On Therapy: A Case Series Of 13 Patients

Frontiers in Immunology, 2022
The role of IgE autoantibodies has been demonstrated in the pathogenesis of bullous pemphigoid for many years. Recently, omalizumab (OMZ), a humanized monoclonal anti-IgE antibody that depletes total serum IgE, has been used off-label in a few case ...
Marina Alexandre, Gérôme Bohelay, Gérôme Bohelay, Thomas Gille, Thomas Gille, Christelle Le Roux-Villet, Isaac Soued, Florence Morin, Frédéric Caux, Frédéric Caux, Sabine Grootenboer-Mignot, Catherine Prost-Squarcioni, Catherine Prost-Squarcioni, Catherine Prost-Squarcioni   +13 more
doaj   +1 more source

Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms

Frontiers in Immunology, 2022
Bullous pemphigoid is an autoimmune blistering disease caused by autoantibodies targeting BP180 and BP230. While deposits of IgG and/or complement along the epidermal basement membrane are typically seen suggesting complement -mediated pathogenesis ...
Connor Cole, Keshavamurthy Vinay, Luca Borradori, Kyle T. Amber, Kyle T. Amber   +4 more
doaj   +1 more source

Use of gliptins reduces levels of SDF-1/CXCL12 in bullous pemphigoid and type 2 diabetes, but does not increase autoantibodies against BP180 in diabetic patients

Frontiers in Immunology, 2022
The use of dipeptidyl peptidase 4 (DPP4) inhibitors, (also known as gliptins), is associated with an increased risk of bullous pemphigoid (BP), an autoimmune blistering skin disease.
Antti Nätynki, Päivi Leisti, Jussi Tuusa, Outi Varpuluoma, Laura Huilaja, Kentaro Izumi, Sanna-Kaisa Herukka, Olavi Ukkola, Juhani Junttila, Nina Kokkonen, Kaisa Tasanen   +10 more
doaj   +1 more source