Results 41 to 50 of about 2,229 (127)

Bullous pemphigoid associated with milia, increased serum IgE, autoantibodies against desmogleins, and refractory treatment in a young patient [PDF]

Anais Brasileiros de Dermatologia, 2017
: Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3).
Shu Ding, Qiancheng Deng, Yaping Xiang, Jing Chen, Jinhua Huang, Jianyun Lu   +5 more
doaj   +1 more source

Hemidesmosomal Proteins in Oral Cancer Progression: An Immunohistochemical Study of Human and Mouse

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Hemidesmosomal subunits have gained attention for their potential role in the progression of oral squamous cell carcinoma (OSCC). However, formal analysis of quantitative expression patterns correlating with OSCC disease pathogenesis remains limited.
Nikhil Mongia, Ali Ibrahim Mohammed, Michael McCullough, Rita Paolini, James A. Rickard, Massimo Mascolo, Silvia Varricchio, Lorraine A. O'Reilly, John Silke, Nicola Cirillo, Antonio Celentano   +10 more
wiley   +1 more source

Case report: Detection of anti-bullous pemphigoid antigen 180 antibodies in a patient with Behçet’s disease

Frontiers in Medicine, 2022
Behçet’s disease (BD) is a systemic inflammatory disease of unknown etiology. BD is characterized by relapsing oral and genital ulcers, several different cutaneous features, relapsing bilateral uveitis, and involvement of internal organs, showing ...
Dario Didona, Antonio Manuel Sequeira Santos, Tomas Cunha, Julia Hinterseher, Jacqueline Kussini, Michael Hertl   +5 more
doaj   +1 more source

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

International Journal of Dermatology, Volume 65, Issue 7, Page 1376-1382, July 2026.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes, Negar Esfandiari, Steven Daveluy   +2 more
wiley   +1 more source

Distinctive Reactivity to the C-terminal Epitope of BP180 Characterizes Immune Checkpoint Inhibitor–associated Bullous Pemphigoid, and an ELISA Based on the BP180 Ectodomain Enables Prompt Diagnosis in a Subset of Patients

Acta Dermato-Venereologica
Growing evidence has linked bullous pemphigoid (BP) to immune checkpoint inhibitor (ICI) therapy in cancer treatment. However, the immunological features of ICI-associated BP (ICI-BP) are not yet fully elucidated.
Anna Pira, Martina Merli, Feliciana Mariotti, Marco Andreani, Angelo Valerio Marzano, Clara De Simone, Rosa Falcone, Giuseppe Testa, Battarra Mariarosa, Maurizio Romagnuolo, Pietro Sollena, Federica De Galitiis, Emiliano Antiga, Roberto Maglie, Dario Didona, Jo Linda Maria Sinagra, Marzia Caproni, Michael Hertl, Emanuele Cozzani, Pamela Vezzoli, Laura Calabrese, Giovanni Paolino, Sofia Verkhovskaia, Luca Fania, Giulia Gasparini, Anna Rita Giampetruzzi, Biagio Didona, Pietro Quaglino, Giovanni Di Zenzo   +28 more
doaj   +1 more source

Dipeptidyl Peptidase-4 Inhibitor-Associated Bullous Pemphigoid

Frontiers in Immunology, 2019
Bullous pemphigoid (BP) is an organ-specific autoantibody-mediated blistering skin disease that mainly affects the elderly. Typical clinical features include the widespread blisters, often preceded by and/or associated with itchy urticarial or eczema ...
Kaisa Tasanen, Outi Varpuluoma, Wataru Nishie   +2 more
doaj   +1 more source

Risk Factors for Mucosal Involvement in Bullous Pemphigoid and the Possible Mechanism: A Review

Frontiers in Medicine, 2021
Bullous pemphigoid (BP) is the most common type of autoimmune bullous disease and is characterized by the presence of circulating anti-BP180 and/or anti-BP230 autoantibodies.
Xinyi Chen, Wenlin Zhao, Hongzhong Jin, Li Li   +3 more
doaj   +1 more source

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1137-1161, July 2026.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source

Anti-Type VII Collagen Antibodies Are Identified in a Subpopulation of Bullous Pemphigoid Patients With Relapse

Frontiers in Immunology, 2018
Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is an uncommon clinical feature of BP which may evoke epidermolysis bullosa acquisita, another ...
Delphine Giusti, Delphine Giusti, Grégory Gatouillat, Grégory Gatouillat, Sébastien Le Jan, Julie Plée, Julie Plée, Philippe Bernard, Philippe Bernard, Frank Antonicelli, Frank Antonicelli, Bach-Nga Pham, Bach-Nga Pham   +12 more
doaj   +1 more source

The significance of preclinical anti-BP180 autoantibodies

Frontiers in Immunology, 2022
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai, Kentaro Izumi, Shoko Mai, Hideyuki Ujiie   +3 more
doaj   +1 more source