Results 1 to 10 of about 1,626 (125)

Serum BP180 and BP230 autoantibodies in Alzheimer’s disease: diagnostic and cognitive associations in a retrospective study [PDF]

Frontiers in Aging Neuroscience
BackgroundTo assess the prevalence and diagnostic value of serum anti-BP180 and anti-BP230 antibodies in Alzheimer’s Disease (AD) and their relationship with cognitive function.MethodsWe conducted a retrospective case–control study comprising 279 ...
Sha Jin, Jie Yu, Huai-Li Liu, Cong Wang, Feng-Ming Zheng   +4 more
doaj   +2 more sources

Deciphering the Contribution of BP230 Autoantibodies in Bullous Pemphigoid

Antibodies, 2022
Bullous pemphigoid (BP) is a subepidermal autoimmune blistering disease predominantly affecting elderly patients and carries significant morbidity and mortality.
, Kyle T Amber, Borradori Luca
exaly   +3 more sources

BP230-Type Bullous Pemphigoid is a Rare Subset of Bullous Pemphigoid Associated With a Favorable Prognosis: A Retrospective Analysis From a Tertiary Referral Center. [PDF]

Int J Dermatol
International Journal of Dermatology, Volume 65, Issue 7, Page 1460-1462, July 2026.
Maglie R, Senatore S, Pipitò C, Baffa ME, Colabrese S, Visinoni S, Rubino V, Pira A, Mariotti F, Caproni M, Di Zenzo G, Antiga E.   +11 more
europepmc   +2 more sources

A case of anti-BP230 antibody-positive bullous pemphigoid receiving DPP-4 inhibitor

Immunological Medicine, 2021
Bullous pemphigoid (BP) is a cutaneous autoimmune blistering disorder. Recently, it has been reported that dipeptidyl peptidase-4 inhibitors (DPP4i) is associated with the development of BP (DPP4i-BP). Patients with DPP4i-BP have autoantibodies (autoAbs)
Tadahiro Kobayashi, Takashi Matsushita, Kazuhiko Takehara   +2 more
exaly   +2 more sources

Evaluation of a novel chemiluminescent immunoassay for autoantibody detection in pemphigus and bullous pemphigoid [PDF]

Frontiers in Immunology
BackgroundA novel fully automated chemiluminescent immunoassay (CLIA) has been developed to quantify autoantibodies specific for desmogleins (Dsg1, Dsg3), BP180, and BP230, key target antigens in pemphigus and bullous pemphigoid.
Na Zhang, Ming Wang, Lili Hou, Yanyu Zhang, Yan Zhao, Luyang Du, Xiaoqing Li, Xia Liu, Hongwei Zhou, Jiaxuan Hao, Jing Tian, Qiuping Yu, Lixia Li, Fangming Cheng, Hai-Zhou Zhou   +14 more
doaj   +2 more sources

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta-Analysis, and Trial Sequential Analysis. [PDF]

J Oral Pathol Med
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Patini R, Gioco G, Mignogna MD, Leuci S, Scilla F, Gentile D, Rupe C, Russo E, Schiavelli A, Lajolo C.   +9 more
europepmc   +2 more sources

The Secretome of Bullous Pemphigoid IgG-Treated Keratinocytes Induces a Pro-Inflammatory Eosinophil Response. [PDF]

Exp Dermatol
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Mansini AP, Bao L, Chhiba KD, Li J, Wang Y, Gainer H, McAlexander MA, McCrae C, Nazaroff CD, Kuang FL, Amber KT.   +10 more
europepmc   +2 more sources

Buccal Mucosa as Substrate for Direct Immunofluorescence Should Be Included Early in the Diagnostic Work Up of Ocular Mucous Membrane Pemphigoid

JEADV Clinical Practice
Background In ocular mucous membrane pemphigoid (MMP) direct immunofluorescence (DIF) represents the gold standard for definitive diagnosis. However, up to 50% of ocular MMP cases do not meet the immunopathological criteria.
Andrea Gabusi, Michelangelo La Placa, Davide Bartolomeo Gissi, Federica Filippi, Camilla Loi, Cosimo Misciali, Federico Bardazzi   +6 more
doaj   +2 more sources

Detection of Diagnostic Antibodies in Immune-Mediated Diseases: A Focus on Antigens and Technologies. [PDF]

Chembiochem
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Bracci S, Real-Fernandez F, Pratesi F, Nuti F, Rovero P, Papini AM.   +5 more
europepmc   +2 more sources

Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment [PDF]

Frontiers in Medicine
ObjectiveThis study aimed to explore the relationship between serum levels of interleukin-17 (IL-17), interleukin-18 (IL-18), interleukin-22 (IL-22), interleukin-25 (IL-25), anti-BP180 antibodies, anti-BP230 antibodies, and immunoglobulin E (IgE) and the
Xinyi Hong, Xinyi Hong, Xinyi Hong, Xinyi Hong, Xiuqin Wang, Xiuqin Wang, Xiuqin Wang, Xiuqin Wang, Yin Cheng, Yin Cheng, Yin Cheng, Yin Cheng, Hanqing Song, Hanqing Song, Hanqing Song, Hanqing Song, Congcong Xu, Congcong Xu, Congcong Xu, Congcong Xu, Peiguang Wang, Peiguang Wang, Peiguang Wang, Peiguang Wang   +23 more
doaj   +2 more sources