Results 21 to 30 of about 2,139 (156)

Gliptin-associated bullous pemphigoid shows peculiar features of anti-BP180 and -BP230 humoral response: Results of a multicenter study

, 2022
Background: Recently, several case-control studies demonstrated an association between gliptins and bullous pemphigoid (BP) occurrence. However, data on the clinical and immunologic features of gliptin-associated bullous pemphigoid (GABP) are ...
Parodi, Aurora, Papini, Manuela, Didona, Biagio, Pallotta, Sabatino, Abeni, Damiano, Festa, Francesca, Lechiancole, Stefania, Di Zenzo, Giovanni, Fania, Luca, Salemme, Adele, Mariotti, Feliciana, Genovese, Giovanni, Scarabello, Alessandra, De Simone, Clara, Bellei, Barbara, Satta, Rosanna Rita, Caproni, Marzia, Passarelli, Francesca, Provini, Alessia, Mazzanti, Cinzia, Marzano, Angelo Valerio, Sordi, Donatella, Cozzani, Emanuele, Feliciani, Claudio, Donatella Sordi, null   +24 more
core   +3 more sources

Purification of the 230-kD Bullous Pemphigoid Antigen (BP230) from Bovine Tongue Mucosa: Structural Analyses and Assessment of BP230 Tissue Distribution Using a New Monoclonal Antibody [PDF]

, 1994
In the epidermis the autoantigen BP230 is a component of the hemidesmosomal plaque. We have developed a procedure for the isolation of BP230 from bovine tongue mucosa using chromatographic means.
Klatte, David H., Jones, Jonathan C.R.
core   +1 more source

The significance of preclinical anti-BP180 autoantibodies

Frontiers in Immunology, 2022
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai, Kentaro Izumi, Shoko Mai, Hideyuki Ujiie   +3 more
doaj   +1 more source

Production of the bullous pemphigoid antigen 230 (BP230) by Saccharomyces cerevisiae and Pichia pastoris

, 2003
BP230 is a cytoskeletal linker protein of 2649 amino acids originally identified as the target autoantigen in bullous pemphigoid, a potentially devastating autoimmune skin blistering disorder.
Saurat, J. H., Monod, M., Koster, J., Fontao, L., Borradori, L., Favre, B., Laffitte, E., Shafaatian, R.   +7 more
core   +3 more sources

Molecular mimicry between BP180/BP230 hemidesmosomal proteins and neural isoforms in the association of bullous pemphigoid with dementia

, 2021
Autoanticorpos direcionados contra as proteínas hemidesmossomais BP180 e/ou BP230, expressas na zona da membrana basal do tegumento, causam penfigoide bolhoso (PB). A associação do PB com a demência tem sido cada vez mais relatada em idosos.
Julio, Tamiris Amanda
core   +1 more source

A comparative study of expression of Fc receptors in relation to the autoantibody-mediated immune response and neutrophil elastase expression in autoimmune blistering dermatoses

Polish Journal of Pathology, 2017
Here we investigated the cutaneous CD32A and CD89 expression in relation to the neutrophil elastase (NE) expression and serum level of anti-desmoglein 1 and 3 (DSG1/DSG3) IgG in pemphigus, anti-BP180/BP230 IgG in bullous pemphigoid (BP), anti-gliadin ...
Justyna Gornowicz-Porowska, Agnieszka Seraszek-Jaros, Monika Bowszyc-Dmochowska, Elżbieta Kaczmarek, Paweł Pietkiewicz, Paweł Bartkiewicz, Marian Dmochowski   +6 more
doaj   +1 more source

Eosinophils, Basophils, and Neutrophils in Bullous Pemphigoid

Biomolecules, 2023
Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal proteins BP180 and BP230.
Maren M. Limberg, Tobias Weihrauch, Natalie Gray, Nancy Ernst, Karin Hartmann, Ulrike Raap   +5 more
doaj   +1 more source

Anti-Type VII Collagen Antibodies Are Identified in a Subpopulation of Bullous Pemphigoid Patients With Relapse

Frontiers in Immunology, 2018
Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is an uncommon clinical feature of BP which may evoke epidermolysis bullosa acquisita, another ...
Delphine Giusti, Delphine Giusti, Grégory Gatouillat, Grégory Gatouillat, Sébastien Le Jan, Julie Plée, Julie Plée, Philippe Bernard, Philippe Bernard, Frank Antonicelli, Frank Antonicelli, Bach-Nga Pham, Bach-Nga Pham   +12 more
doaj   +1 more source

Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms

Frontiers in Immunology, 2022
Bullous pemphigoid is an autoimmune blistering disease caused by autoantibodies targeting BP180 and BP230. While deposits of IgG and/or complement along the epidermal basement membrane are typically seen suggesting complement -mediated pathogenesis ...
Connor Cole, Keshavamurthy Vinay, Luca Borradori, Kyle T. Amber, Kyle T. Amber   +4 more
doaj   +1 more source

Autoantibody Profile of a Cohort of 54 Italian Patients with Linear IgA Bullous Dermatosis: LAD-1 Denoted as a Major Auto-antigen of the Lamina Lucida Subtype

Acta Dermato-Venereologica, 2020
Linear IgA bullous dermatosis (LABD) is characterized by presence of multiple IgA autoantibodies, and a comparatively lesser number of IgG antibodies, directed against different hemidesmosomal antigens. The main autoantigens are LAD-1, LABD-97, BP180 and
Emanuele Cozzani, Giovanni di Zenzo, Giulia Gasparini, Adele Salemme, Arianna Fay Agnoletti, Camilla Vassallo, Marzia Caproni, Emiliano Antiga, Angelo V. Marzano, Riccardo Cavalli, Corrado Ocella, Clara De Simone, Aurora Parodi   +12 more
doaj   +1 more source