Results 21 to 30 of about 1,676 (161)

Anti‐BP230 antibody–positive bullous pemphigoid complicated by ulcerative colitis [PDF]

Journal of Cutaneous Immunology and Allergy, 2019
Mayu Fujimoto, Yasutomo Imai, Chiharu Tateishi, Daisuke Tsuruta, Kiyofumi Yamanishi   +4 more
doaj   +2 more sources

Autoreactive Peripheral Blood T Helper Cell Responses in Bullous Pemphigoid and Elderly Patients With Pruritic Disorders

Frontiers in Immunology, 2021
Bullous pemphigoid (BP) is a prototypic autoimmune disorder of the elderly, characterized by serum IgG autoantibodies, namely anti-BP180 and anti-BP230, directed against components of the basal membrane zone that lead to sub-epidermal loss of adhesion ...
Dario Didona, Luca Scarsella, Milad Fehresti, Farzan Solimani, Farzan Solimani, Hazem A. Juratli, Manuel Göbel, Stefan Mühlenbein, Lily Holiangu, Josquin Pieper, Vera Korff, Thomas Schmidt, Cassian Sitaru, Rüdiger Eming, Michael Hertl, Robert Pollmann   +15 more
doaj   +1 more source

Analysis of the autoimmune response against BP180 and BP230 in ethnic Poles with neurodegenerative disorders and bullous pemphigoid

Central European Journal of Immunology, 2017
Recent studies postulated the association between bullous pemphigoid (BP) and neurodegenerative disorders (ND). The autoantibodies to BP180 and/or BP230 may be present not only in BP, but also in ND as neuronal isoforms of these proteins are identified ...
Justyna Gornowicz-Porowska, Agnieszka Seraszek-Jaros, Monika Bowszyc-Dmochowska, Elżbieta Kaczmarek, Paweł Pietkiewicz, Paweł Bartkiewicz, Marian Dmochowski   +6 more
doaj   +1 more source

The significance of preclinical anti-BP180 autoantibodies

Frontiers in Immunology, 2022
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai, Kentaro Izumi, Shoko Mai, Hideyuki Ujiie   +3 more
doaj   +1 more source

High Index Values of Enzyme-Linked Immunosorbent Assay for BP180 at Baseline Predict Relapse in Patients With Bullous Pemphigoid

Frontiers in Medicine, 2018
Bullous pemphigoid (BP) presenting with erythema plaques and tense blisters is the most frequent autoimmune bullous disease. Immunologically, BP is characterized by the presence of circulating anti-epidermal basement membrane zone (BMZ) antibodies.
Hiroshi Koga, Kwesi Teye, Norito Ishii, Chika Ohata, Takekuni Nakama   +4 more
doaj   +1 more source

A comparative study of expression of Fc receptors in relation to the autoantibody-mediated immune response and neutrophil elastase expression in autoimmune blistering dermatoses

Polish Journal of Pathology, 2017
Here we investigated the cutaneous CD32A and CD89 expression in relation to the neutrophil elastase (NE) expression and serum level of anti-desmoglein 1 and 3 (DSG1/DSG3) IgG in pemphigus, anti-BP180/BP230 IgG in bullous pemphigoid (BP), anti-gliadin ...
Justyna Gornowicz-Porowska, Agnieszka Seraszek-Jaros, Monika Bowszyc-Dmochowska, Elżbieta Kaczmarek, Paweł Pietkiewicz, Paweł Bartkiewicz, Marian Dmochowski   +6 more
doaj   +1 more source

Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms

Frontiers in Immunology, 2022
Bullous pemphigoid is an autoimmune blistering disease caused by autoantibodies targeting BP180 and BP230. While deposits of IgG and/or complement along the epidermal basement membrane are typically seen suggesting complement -mediated pathogenesis ...
Connor Cole, Keshavamurthy Vinay, Luca Borradori, Kyle T. Amber, Kyle T. Amber   +4 more
doaj   +1 more source

Anti-Type VII Collagen Antibodies Are Identified in a Subpopulation of Bullous Pemphigoid Patients With Relapse

Frontiers in Immunology, 2018
Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is an uncommon clinical feature of BP which may evoke epidermolysis bullosa acquisita, another ...
Delphine Giusti, Delphine Giusti, Grégory Gatouillat, Grégory Gatouillat, Sébastien Le Jan, Julie Plée, Julie Plée, Philippe Bernard, Philippe Bernard, Frank Antonicelli, Frank Antonicelli, Bach-Nga Pham, Bach-Nga Pham   +12 more
doaj   +1 more source

Eosinophils, Basophils, and Neutrophils in Bullous Pemphigoid

Biomolecules, 2023
Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal proteins BP180 and BP230.
Maren M. Limberg, Tobias Weihrauch, Natalie Gray, Nancy Ernst, Karin Hartmann, Ulrike Raap   +5 more
doaj   +1 more source

Autoantibody Profile of a Cohort of 54 Italian Patients with Linear IgA Bullous Dermatosis: LAD-1 Denoted as a Major Auto-antigen of the Lamina Lucida Subtype

Acta Dermato-Venereologica, 2020
Linear IgA bullous dermatosis (LABD) is characterized by presence of multiple IgA autoantibodies, and a comparatively lesser number of IgG antibodies, directed against different hemidesmosomal antigens. The main autoantigens are LAD-1, LABD-97, BP180 and
Emanuele Cozzani, Giovanni di Zenzo, Giulia Gasparini, Adele Salemme, Arianna Fay Agnoletti, Camilla Vassallo, Marzia Caproni, Emiliano Antiga, Angelo V. Marzano, Riccardo Cavalli, Corrado Ocella, Clara De Simone, Aurora Parodi   +12 more
doaj   +1 more source