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This poster was presented at the Biennial Structural Biology Conference "Structural Biology: Deeper into the Cell", organized by Instruct-ERIC (https://instruct-eric.eu/biennial2019), which was held in Alcalá de Henares (Spain) from May 22 till May 24 ...
Gómez-Hernández, María +8 more
core +1 more source
Tocilizumab for severe and refractory mucous membrane pemphigoid
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt +20 more
wiley +1 more source
Mechanical stability of epithelia requires firm attachment to the basement membrane via hemidesmosomes. Dysfunction of hemidesmosomal proteins causes severe skin-blistering diseases.
Gómez-Hernández, María +8 more
core +1 more source
Refractory Pemphigoid with Autoantibodies to Both BP230 and Laminin gamma1
is missing (Short communication)
Himino Ashida +8 more
doaj +1 more source
: Bullous pemphigoid is the most frequent autoimmune bullous disease and mainly affects elderly individuals. Increase in incidence rates in the past decades has been attributed to population aging, drug-induced cases and improvement in the diagnosis of ...
Denise Miyamoto +3 more
doaj +2 more sources
Bullous Pemphigoid: Trigger and Predisposing Factors
Bullous pemphigoid (BP) is the most frequent autoimmune subepidermal blistering disease provoked by autoantibodies directed against two hemidesmosomal proteins: BP180 and BP230.
Francesco Moro +4 more
doaj +1 more source
Case report: Minimal manifestations of mucous membrane pemphigoid in a young adult
A male patient presented to our department at the age of 23 suffering from recurrent painful erosions in the urethral outlet area. In closer clinical examination gingival erosions, primarily around the teeth were identified as well.
Franziska Schauer +2 more
doaj +1 more source
Epidermolysis Bullosa Classification and Current Approach to Diagnosis
ABSTRACT Epidermolysis bullosa (EB) is a heterogeneous group of rare genodermatoses marked by skin fragility and bullae formation induced by minor trauma. Pathologic variants in at least 21 genes are associated with EB, grouped into four major subtypes based predominantly on the plane of cleavage within the skin.
Hannah E. Mumber, Marissa J. Perman
wiley +1 more source
39 bullous pemphigoid (BP) patients were studied to assess the clinical significance of anti-BP180 and anti-BP230 circulating autoantibodies of BP and correlate their titers with the clinical scores of the BP Disease Area Index (BPDAI) and the Autoimmune
Aikaterini Patsatsi +4 more
doaj +1 more source
Bullous pemphigoid (BP), the most common autoimmune blistering disease, is induced by autoantibodies to type XVII collagen (COL17). Previous studies demonstrated that COL17 harbors several epitopes targeted by autoreactive T and B cells and that the ...
Hideyuki Ujiie +6 more
doaj +1 more source

