Results 31 to 40 of about 1,676 (161)

Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

Frontiers in Medicine, 2021
Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ ...
Anna Rosińska-Więckowicz, Magdalena Jałowska, Monika Bowszyc-Dmochowska, Marian Dmochowski   +3 more
doaj   +1 more source

Analysis of the interactions between BP180, BP230, plectin and the integrin α6β4 important for hemidesmosome assembly [PDF]

Journal of Cell Science, 2003
Hemidesmosomes (HDs) are multi-protein complexes that promote stable adhesion of epithelial cells to the underlying extracellular matrix. We assessed the interactions between different hemidesmosomal components with each other, mapped the binding sites and studied the importance of these interactions for HD assembly in yeast two-hybrid and cell ...
Koster, Jan, Geerts, Dirk, Favre, Bertrand, Borradori, Luca, Sonnenberg, Arnoud   +4 more
openaire   +2 more sources

Evaluation of ELISA BP180 and BP230 Autoantibodies in Blister Fluid and Serum in the Diagnosis of Bullous Pemphigoid

Indian Journal of Dermatology, 2023
Bullous pemphigoid (BP) is a chronic subepidermal immunobullous disorder. Studies have demonstrated the presence of antibasement membrane zone antibodies (BP180 & BP230) in the blister fluid using enzyme-linked immunosorbent assay (ELISA).
Harish Nagarajan, Krishnaswamy Mahadevan, Reena Rai, Appalaraju Boppe   +3 more
openaire   +3 more sources

Identification of two novel bullous pemphigoid- associated alleles, HLA-DQA1*05:05 and -DRB1*07:01, in Germans

Orphanet Journal of Rare Diseases, 2021
Bullous pemphigoid (BP) is the most common autoimmune skin blistering disease characterized by autoimmunity against the hemidesmosomal proteins BP180, type XVII collagen, and BP230. To elucidate the genetic basis of susceptibility to BP, we performed the
Christian Schwarm, Damian Gola, Maike M. Holtsche, Anabelle Dieterich, Anita Bhandari, Miriam Freitag, Peter Nürnberg, Mohammad Toliat, Wolfgang Lieb, Michael Wittig, André Franke, Margitta Worm, Michael Sticherling, Jan Ehrchen, Claudia Günther, Regine Gläser, Wiebke K. Peitsch, Miklós Sárdy, Rüdiger Eming, Michael Hertl, Sandrine Benoit, Matthias Goebeler, Claudia Pföhler, Manfred Kunz, Alexander Kreuter, Nina van Beek, Jeanette Erdmann, Hauke Busch, Detlef Zillikens, Christian D. Sadik, Misa Hirose, Inke R. König, Enno Schmidt, Saleh M. Ibrahim, German AIBD Study Group   +34 more
doaj   +1 more source

Paraneoplastic Pemphigus Presenting as Mild Cutaneous Features of Pemphigus Foliaceus and Lichenoid Stomatitis with Antidesmoglein 1 Antibodies

Dermatology Research and Practice, 2010
Herein, we report a case of paraneoplastic pemphigus with mild skin features of pemphigus foliaceus and lichenoid stomatitis associated with B-cell lymphoma. A 49-year-old man presented with scattered blisters and erosions on the trunk along with mucosal
Yayoi Niimi, Bungo Ohyama, Giovanni Di Zenzo, Valentina Calabresi, Takashi Hashimoto, Seiji Kawana   +5 more
doaj   +1 more source

Incidence of P200 pemphigoid: A nationwide study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen, Marion Carrette, Marie‐Laure Golinski, Maud Maho‐Vaillant, Alexis Lefebvre, André Gillibert, Pascal Joly, Vivien Hébert   +7 more
wiley   +1 more source

Tocilizumab for severe and refractory mucous membrane pemphigoid

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt, Maud Maho‐Vaillant, Julie Gueudry, Marie‐Laure Golinski, Marion Marcaillou, Blanche Bergeret, Guillaume Chambon, Pierre Bouchetemble, Soumeya Bekri, Abdellah Tebani, Hervé Maillard, Cécile Morice, Anais Vautier, Edgar‐Pierre Libert, Christelle Le Roux‐Villet, Marion Carrette, Olivier Boyer, Vivien Hébert, Sébastien Calbo, André Gillibert, Pascal Joly   +20 more
wiley   +1 more source

Purification of the 230-kD Bullous Pemphigoid Antigen (BP230) from Bovine Tongue Mucosa: Structural Analyses and Assessment of BP230 Tissue Distribution Using a New Monoclonal Antibody

Journal of Investigative Dermatology, 1994
In the epidermis the autoantigen BP230 is a component of the hemidesmosomal plaque. We have developed a procedure for the isolation of BP230 from bovine tongue mucosa using chromatographic means. The identity of the isolated protein was confirmed by its recognition by bullous pemphigoid autoantibodies. A monoclonal antibody (MoAb230), generated against
Klatte, David H., Jones, Jonathan C.R.
openaire   +2 more sources

Bullous pemphigoid [PDF]

Anais Brasileiros de Dermatologia
: Bullous pemphigoid is the most frequent autoimmune bullous disease and mainly affects elderly individuals. Increase in incidence rates in the past decades has been attributed to population aging, drug-induced cases and improvement in the diagnosis of ...
Denise Miyamoto, Claudia Giuli Santi, Valéria Aoki, Celina Wakisaka Maruta   +3 more
doaj   +2 more sources

A Case of Bullous Rash Apparently Triggered by Meningococcal and Rotavirus Vaccines in an Infant: Focus on Infantile Bullous Pemphigoid

Dermatopathology, 2021
Bullous pemphigoid (BP) is an autoimmune bullous disease and is a rare condition in childhood. Acquired tense acral bullae and fixed urticarial annular lesions on the trunk are diagnostic clues of infantile BP.
Iria Neri, Valeria Evangelista, Alba Guglielmo, Andrea Sechi, Annalucia Virdi   +4 more
doaj   +1 more source