Results 111 to 120 of about 830 (135)

Gastric Pentadecapeptide BPC 157 and Short Bowel Syndrome in Rats

Digestive Diseases and Sciences, 2008
The gastric pentadecapeptide BPC 157, which was shown to be safe as an antiulcer peptide in trials for inflammatory bowel disease (PL14736, Pliva), successfully healed intestinal anastomosis and fistula in rat. Therefore, we studied for 4 weeks rats with escalating short bowel syndrome and progressive weight loss after small bowel resection from fourth
Sever, Marko, Kliček, Robert, Radić, Božo, Brčić, Luka, Zoričić, Ivan, Drmić, Domagoj, Ivica, Mihovil, Barišić, Ivan, Ilić, Spomenko, Berkopić, Lidija, Boban Blagaić, Alenka, Ćorić, Marijana, Kolenc, Danijela, Vrčić, Hrvoje, Anić, Tomislav, Seiwerth, Sven, Sikirić, Predrag   +16 more
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Focus on Ulcerative Colitis: Stable Gastric Pentadecapeptide BPC 157

Current Medicinal Chemistry, 2012
Stable gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, M.W. 1419) may be the new drug stable in human gastric juice, effective both in the upper and lower GI tract, and free of side effects. BPC 157, in addition to an antiulcer effect efficient in therapy of inflammatory bowel disease (IBD) (PL 14736) so far only tested in clinical phase II, has a ...
P, Sikiric, S, Seiwerth, R, Rucman, B, Turkovic, D S, Rokotov, L, Brcic, M, Sever, R, Klicek, B, Radic, D, Drmic, S, Ilic, D, Kolenc, V, Stambolija, Z, Zoricic, H, Vrcic, B, Sebecic   +15 more
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Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury

Regulatory Peptides, 2010
We focused on the healing of rat transected sciatic nerve and improvement made by stable gastric pentadecapeptide BPC 157 (10 microg, 10ng/kg) applied shortly after injury (i) intraperitoneally/intragastrically/locally, at the site of anastomosis, or after (ii) non-anastomozed nerve tubing (7 mm nerve segment resected) directly into the tube ...
Gjurašin, Miroslav, Miklić, Pavle, Župančić, Božidar, Perović, Darko, Žarković, Kamelija, Brčić, Luka, Kolenc, Danijela, Radić, Božo, Seiwerth, Sven, Sikirić, Predrag   +9 more
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Antiinflammatory effect of BPC 157 on experimental periodontitis in rats.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009
The pentadecapeptide BPC 157 has been shown to have anti-inflammatory and wound healing effects on multiple target tissues and organs. The purpose of the present study was to investigate the effect of BPC 157 on inflammation and bone resorption in experimental periodontitis in rats.
Kerémi, B., Lohinai, Z., Komora, P., Duhaj, S., Borsi, K., Jobbágy-óvári, G., Kálló, K., Székely, A.D., Fazekas, A., Dobó-Nagy, C., Sikirić, Predrag, Varga, G.   +11 more
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Traumatic brain injury in mice and pentadecapeptide BPC 157 effect

Regulatory Peptides, 2010
Gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, an anti-ulcer peptide, efficient in inflammatory bowel disease trials (PL 14736), no toxicity reported, improved muscle crush injury. After an induced traumatic brain injury (TBI) in mice by a falling weight, BPC 157 regimens (10.0microg, 10.0ng/kgi.p.) demonstrated a marked attenuation of damage with ...
Tudor, Mario, Jandrić, Ivan, Marović, Anton, Gjurašin, Miroslav, Perović, Darko, Radić, Božo, Boban Blagaić, Alenka, Kolenc, Danijela, Brčić, Luka, Žarković, Kamelija, Seiwerth, Sven, Sikirić, Predrag   +11 more
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The Role of Pentadecapeptide BPC 157 in angiogenesis and NO-synthesis

1997
A clear protection of G-I tract and an evident anti-inflammatory effect were shown for a novel stomach pentadecapeptide BPC(i.p./i.g.) in comparison with several reference standards in various ulcer models alog with a protection of endothelium. Thus, in the first experiments we evaluated whether this pentadecapeptide and other gastroprotective agents ...
Sikirić, Predrag, Hanževački, Miro, Seiwerth, Sven, Grabarević, Željko, Turković, Branko, Ručman, Rudolf, Petek, Marina, Miše, Stjepan, Rotkvić, Ivo, Jagić, Vjekoslav, Šeparović, Jadranka, Konjevoda, Paško, Petrov, G., Prkačin, Ingrid, Zoričić, Ivan, Perović, Darko, Bratulić, Mirna, Artuković, Branka, Tišljar, Marina   +18 more
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The pharmacological properties of the novel peptide BPC 157 (PL-10)

Inflammopharmacology, 1999
The reported beneficial effects of the gastric mucosal derived pentadecapeptide BPC 157 (Gly Glu Pro Pro Pro Gly Lys Pro Ala Asp Asp Ala Gly Leu Val, M.W. 1419) on different organ lesions are reviewed. Apart from the effects on various gastrointestinal lesions, the potentially beneficial effect on pancreas, liver injuries, endothelium and heart damage,
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Protuupalni učinak pentadekapeptida BPC 157

1998
U svim istraživanim upalnim modelima, karageninski edem šape - model akutne upale, terpentinski bukalni edem - model subakutne upale i adjuvantni artritis model kronične upale, BPC 157 je pokazao izrazito protuupalno djelovanje. U karageninskom upalnom modelu BPC 157 dovodi do značajnog smanjenja edema, a učinak je sličan učinku acetilsalicilne ...
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Pentadecapeptide BPC 157 and head injury

2004
Pentadecapeptide BPC 157 and head ...
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Peptides: AOD-9604 & BPC-157

2021
Nguyen, Jennifer Tram, Henderson, Bryn, Choi, Rebecca   +2 more
openaire   +1 more source