Results 101 to 110 of about 261,882 (142)

Portal triad obstruction and reperfusion in rats –the effect of BPC 157 [PDF]

, 2019
To investigate effects of pentadecapeptide BPC 157 therapy in temporary portal triad obstruction – PTO (hepatic artery, portal vein, common bile duct, 30 min in rats), and in reperfusion period thereafter, during 15 min and 24 h. BPC 157 (10 μg/kg, 10 ng/
Dretar, Vilim, Filip Radevski, Tajana Đurašin, Borna Vrdoljak, Mariam Samara, Helena Žižek, Dominik Malekinušić, Vrdoljak, Borna, Malekinušić, Dominik, Žižek, Helena, Samara, Mariam, Radevski, Filip, Vilim Dretar, Đurašin, Tajana   +13 more
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Pentadekapeptid BPC 157 i reperfuzijska ozljeda

, 2018
U ovom diplomskom radu želimo pojasniti na koji način stabilni želučani pentadekapeptid BPC 157 sudjeluje u liječenju reperfuzijske ozljede i njegovo međudjelovanje sa NO sustavom. BPC 157 ima vrlo značajan učinak u cijeljenju, a isto tako utječe i na sve događaje koji uslijede nakon gubitka vaskularnog integriteta (ovisno o uvjetima, on smanjuje ...
openaire   +1 more source

The effect of BPC-157 on proliferation of primary mesenchymal stem/ stromal cells in vitro

Dosedanje raziskave so dokazale, da BPC 157 pozitivno učinkuje pri celjenju različnih tkiv po travmatičnih in sistematskih poškodbah, vendar za uporabo na ljudeh še potrebujemo klinične študije. BPC 157 izboljša sposobnost hemostaze ter funkcijo žil, ima
Hohnjec, Karlina
core  

Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing

Current Reviews in Musculoskeletal Medicine
McGuire, Flynn P., Martinez, Riley, Lenz, Annika, Skinner, Lee, Cushman, Daniel M.   +4 more
openaire   +2 more sources

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BPC 157's effect on healing

Journal of Physiology-Paris, 1997
The 15 amino acid agent BPC 157, showing a wide range of organoprotective action in different experimental models, was used in our experiments in order to establish its influence on different elements connected with the healing process. Elements thought to be of greatest importance in the process of healing are formation of granulation tissue ...
Seiwerth, Sven, Sikirić, Predrag, Grabarević, Željko, Zoričić, Ivan, Hanževački, Miro, Ljubanović, Danica, Ćorić, Vedran, Konjevoda, Paško, Petek, Marijan, Ručman, Rudolf, Turković, Branko, Perović, Darko, Mikuš, Darko, Jandrijević, Stipe, Medvidović, M., Tadić, Tamara, Romac, Branka, Kos, Josip, Perić, Josip, Kolega, Marko   +19 more
openaire   +4 more sources

BPC 157: The counteraction of succinylcholine, hyperkalemia, and arrhythmias

European Journal of Pharmacology, 2016
After the demonstration of its life-saving effect in severe hyperkalemia and the recovery of skeletal muscle after injury, pentadecapeptide BPC 157 has been shown to attenuate the local paralytic effect induced by succinylcholine, in addition to systemic muscle disability (and consequent muscle damage).
Sandra Uzun, Sven Seiwerth, Predrag Sikiric   +2 more
exaly   +4 more sources

Perforating corneal injury in rat and pentadecapeptide BPC 157

Experimental Eye Research, 2015
Based on its healing effects in various tissues, we hypothesized that the stable gastric pentadecapeptide BPC 157 heals corneal ulcerations in rats and effects corneal transparency. We made a penetrant linear 2-mm incision in the paralimbal region of the left cornea at the 5 o'clock position with a 20-gauge MVR incision knife at 45° under an operating ...
Robert Klicek, Antonio Kokot, Sven Seiwerth   +2 more
exaly   +3 more sources

Stable gastric pentadecapeptide BPC 157 and bupivacaine

European Journal of Pharmacology, 2016
Bupivacaine toxicity following accidental overdose still lacks therapeutic solution. However, there are major arguments for testing BPC 157 against bupivacaine toxicity in vivo in rats, in particular, and then finally, in vitro. These are: the lack of any known BPC 157 toxicity, a lifesaving effect via the mitigation of arrhythmias in rats underwent ...
Martina Lovric Bencic, Sandra Uzun, Josipa Vlainić   +2 more
exaly   +4 more sources

BPC 157 and Blood Vessels

Current Pharmaceutical Design, 2014
This review focuses on the described effects of BPC 157 on blood vessels after different types of damage, and elucidate by investigating different aspects of vascular response to injury (endothelium damage, clotting, thrombosis, vasoconstriction, vasodilatation, vasculoneogenesis and edema formation) especially in connection to the healing processes ...
Seiwerth, Sven, Brčić, Luka, Batelja Vuletić, Lovorka, Kolenc, Danijela, Aralica, Gorana, Mišić, Marija, Zenko, Anita, Drmić, Domagoj, Rucman, Rudolf, Sikirić, Pradrag   +9 more
openaire   +2 more sources

Stable Gastric Pentadecapeptide BPC 157-NO-system Relation

Current Pharmaceutical Design, 2014
We reviewed stable gastric pentadecapeptide BPC 157-NO-system-relation, its close participation in Moncada's (maintained vascular integrity, platelets control) homeostatic healing response of NO-system to injury. Namely, BPC 157's particular healing effect also affects all events after vascular integrity loss (dependent on circumstances, it reduces ...
Sikirić, Predrag, Seiwerth, Sven, Ručman, Rudolf, Turković, Branko, Stančić - Rokotov, Dinko, Brčić, Luka, Sever, Marko, Kliček, Robert, Radić, Božo, Drmić, Domagoj, Ilić, Spomenko, Kolenc, Danijela, Aralica, Gorana, Stupnišek, Marijana, Šuran, Jelena, Barišić, Ivan, Džidić, Senka, Vrčić, Hrvoje, Šebečić, Božidar   +18 more
openaire   +4 more sources