Results 81 to 90 of about 261,882 (142)

Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro

Drug Design, Development and Therapy, 2015
Tonglie Huang,1,* Kuo Zhang,2,* Lijuan Sun,3 Xiaochang Xue,1 Cun Zhang,1 Zhen Shu,1 Nan Mu,1 Jintao Gu,1 Wangqian Zhang,1 Yukun Wang,1 Yingqi Zhang,1 Wei Zhang1 1State Key Laboratory of Cancer Biology, Department of Biopharmaceutics, School of Pharmacy,
Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z, Mu N, Gu J, Zhang W, Wang Y, Zhang Y, Zhang W   +11 more
doaj  

Pentadecapeptide BPC 157 Shortens Duration of Tetracaine- and Oxybuprocaine-Induced Corneal Anesthesia in Rats

Acta Clinica Croatica, 2020
We focused on the relationship of 0.5% tetracaine- and 0.4% oxybuprocaine-induced corneal anesthesia in rats, and pentadecapeptide BPC 157 (0.4 μg/eye), along with nitric oxide synthase (NOS) inhibitor N(gamma)-nitro-L-arginine methyl ester (L-NAME) (0.1
Ivan Mirković, Tamara Kralj, Marin Lozić, Vasilije Stambolija, Josip Kovačević, Luka Vrdoljak, Mirna Zlatar, Kristina Milanović, Domagoj Drmić, Jurica Predović, Sanja Masnec, Matija Jurjević, Mladen Bušić, Sven Seiwerth, Antonio Kokot, Predrag Sikirić   +15 more
doaj   +1 more source

Unilateral Adrenalectomy, and the Stable Pentadecapeptide BPC 157 as Therapy in Rats—A Cytoprotection Approach

Pharmaceuticals
Background. This rat study reveals a new point: the considerable impact of unilateral adrenalectomy, severe vascular and multiorgan failure, occlusion/occlusion-like syndrome, and the stable gastric pentadecapeptide BPC 157 therapy.
Ivan Maria Smoday, Vlasta Vukovic, Katarina Oroz, Hrvoje Vranes, Luka Kalogjera, Ozren Gamulin, Josipa Vlainic, Marija Milavic, Suncana Sikiric, Nora Nikolac Gabaj, Domagoj Marijancevic, Antun Koprivanac, Laura Tomic, Sanja Strbe, Ivan Barisic, Lidija Beketic Oreskovic, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic   +21 more
doaj   +1 more source

Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats

World Journal of Gastroenterology, 2004
To investigate the protective effects of gastric pentadecapeptide BPC 157 on acute and chronic gastric ulcers in rats and to compare the results in therapy of human gastric ulcers by different administration methods.Gastric pentadecapeptide BPC 157 was administered (initial single or continuous administration) into rats either intragastrically or ...
Xiao-Chang, Xue, Yong-Jie, Wu, Ming-Tang, Gao, Wen-Guang, Li, Ning, Zhao, Zeng-Lu, Wang, Chun-Jie, Bao, Zhen, Yan, Ying-Qi, Zhang   +8 more
openaire   +2 more sources

BPC 157 Therapy Heals Tendon Muscle Junction in Rats

The FASEB Journal, 2018
Aim After tendon was separated from muscle in the right quadriceps muscle in rats, we focused on the tendon‐muscle junction healing and therapy with the stable gastric pentadecapeptide BPC 157. Noteworthy, BPC 157 is an original antiulcer peptide, stable in human gastric juice, used in ulcerative colitis and now
Japjec, Mladen, Staresinic, Mario, Sebecic, Bozidar, Pavlov, Katarina Horvat, Drmic, Domagoj, Vidovic, Tinka, Vlainic, Josipa, Seiwerth, Sven, Sikiric, Predrag   +8 more
openaire   +1 more source

Antagonizacija učinka intramuskularne aplikacije sukcinilkolina u štakora primjenom pentadekapeptida BPC 157 [Antagonisation of intramuscular application of succinycholine in rats by pentadecapeptide BPC 157] [PDF]

, 2016
Pentadecapeptide BPC 157 improves muscle healing and has neuroprotective properties. We tested BPC 157 counteracting effect on intramuscular application of succinylcholine.
Stambolija, Vasilije
core   +1 more source

Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury

Medicina
Background and Objectives: Ischemia–reperfusion (I/R) injury can affect multiple distant organs following I/R in the lower extremities. BPC-157’s anti-inflammatory and free radical-neutralizing properties suggest its potential in mitigating ischemia ...
Hüseyin Demirtaş, Abdullah Özer, Alperen Kutay Yıldırım, Ali Doğan Dursun, Şaban Cem Sezen, Mustafa Arslan   +5 more
doaj   +1 more source

Učinak pentadekapeptida BPC 157 na tubularnu nekrozu u štakora izazvanu gentamicinom [PDF]

, 2019
Introduction: we have investigated the effect of pentadecapeptide BPC 157 on aminoglycoside nephrotoxicity (AN) in the rats after application of high dose of gentamicin.
Vukoja, Ivan
core   +1 more source

New findings on stable gastric pentadecapeptide BPC 157

, 2019
Stabilni želučani pentadekapeptid BPC 157 je novi peptid protiv želučanih vrijedova, koji se koristi u ispitivanjima za liječenje ulceroznog kolitisa i sada multiple skleroze.
Vrdoljak, Borna
core   +1 more source

Tendon, Ligament, and Muscle Injury, Osteotendinous, Myotendinous, and Muscle-to-Bone Junction Therapy Perspectives with Growth Factors and Stable Gastric Pentadecapeptide BPC 157—A Review

Pharmaceuticals
As a novel theoretical and practical advantage, preclinical to clinical evidence, this systematic review of PRP, growth factors, and stable gastric pentadecapeptide BPC 157 efficacy in complex musculoskeletal and junctional injuries emphasizes the ...
Danijel Matek, Irena Matek, Mladen Japjec, Mirta Matek, Jakov Prenc, Borna Staresinic, Eva Staresinic, Andreja Prtoric, Suncana Sikiric, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic, Ivan Bojanic, Ivan Dobric, Mario Staresinic   +20 more
doaj   +1 more source