In relation to NO-System, Stable Pentadecapeptide BPC 157 Counteracts Lidocaine-Induced Adverse Effects in Rats and Depolarisation In Vitro [PDF]
Emergency Medicine International, 2020 Recently, the pentadecapeptide BPC 157-induced counteraction of bupivacaine cardiotoxicity has been reported. Medication includes (i) lidocaine-induced local anesthesia via intraplantar application and axillary and spinal (L4-L5) intrathecal block, (ii ...
Marin Lozic +16 more
doaj +3 more sources
Stable Gastric Pentadecapeptide BPC 157 Therapy for Monocrotaline-Induced Pulmonary Hypertension in Rats Leads to Prevention and Reversal [PDF]
Biomedicines, 2021 Background. Monocrotaline selectively injures the lung’s vascular endothelium and induces pulmonary arterial hypertension. The stable gastric pentadecapeptide BPC 157 acts as a prototype cytoprotective agent that maintains endothelium, and its ...
Dean Strinic +2 more
exaly +4 more sources
Stable Gastric Pentadecapeptide BPC 157 and Striated, Smooth, and Heart Muscle [PDF]
Biomedicines, 2022 First, we review the definitively severed myotendinous junction and recovery by the cytoprotective stable gastric pentadecapeptide BPC 157 therapy, its healing that might combine both transected and detached tendon and transected muscle, ligament and ...
Antonio Kokot +2 more
exaly +4 more sources
The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats [PDF]
Brain and Behavior, 2020 Background and purpose We focused on the, yet undescribed, therapy effect of the stable gastric pentadecapeptide BPC 157 in hippocampal ischemia/reperfusion injuries, after bilateral clamping of the common carotid arteries in rats.
Jakša Vukojević +10 more
doaj +3 more sources
Over-Dose Lithium Toxicity as an Occlusive-like Syndrome in Rats and Gastric Pentadecapeptide BPC 157 [PDF]
Biomedicines, 2021 Due to endothelial impairment, high-dose lithium may produce an occlusive-like syndrome, comparable to permanent occlusion of major vessel-induced syndromes in rats; intracranial, portal, and caval hypertension, and aortal hypotension; multi-organ ...
Dean Strinic +2 more
exaly +4 more sources
Pentadecapeptide BPC 157 and the central nervous system [PDF]
Neural Regeneration Research, 2022 We reviewed the pleiotropic beneficial effects of the stable gastric pentadecapeptide BPC 157, three very recent demonstrations that may be essential in the gut-brain and brain-gut axis operation, and therapy application in the central nervous system ...
Jakša Vukojevic +11 more
doaj +2 more sources
Pentadecapeptide BPC 157 as Therapy for Inferior Caval Vein Embolization: Recovery of Sodium Laurate-Post-Embolization Syndrome in Rats [PDF]
Pharmaceuticals, 2023 After inferior caval vein embolization therapy, post-embolization syndrome (sodium laurate 10 mg/kg, 0.1 mL into rat inferior caval vein, assessment at 15, 30, 60 min, prime lung lesions, thromboemboli occluding lung vessels), as a severe occlusion ...
Ivan Maria Smoday +27 more
doaj +2 more sources
Stable Gastric Pentadecapeptide BPC 157—Possible Novel Therapy of Glaucoma and Other Ocular Conditions [PDF]
Pharmaceuticals, 2023 Recently, stable gastric pentadecapeptide BPC 157 therapy by activation of collateral pathways counteracted various occlusion/occlusion-like syndromes, vascular, and multiorgan failure, and blood pressure disturbances in rats with permanent major vessel ...
Predrag Sikiric +23 more
doaj +2 more sources
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing [PDF]
Frontiers in Pharmacology, 2021 Significance: The antiulcer peptide, stable gastric pentadecapeptide BPC 157 (previously employed in ulcerative colitis and multiple sclerosis trials, no reported toxicity (LD1 not achieved)), is reviewed, focusing on the particular skin wound therapy ...
Sven Seiwerth +23 more
doaj +2 more sources
Stable Gastric Pentadecapeptide BPC 157 Therapy of Rat Glaucoma [PDF]
Biomedicines, 2021 Cauterization of three episcleral veins (open-angle glaucoma model) induces venous congestion and increases intraocular pressure in rats. If not upgraded, one episcleral vein is regularly unable to acquire and take over the whole function, and glaucoma ...
Tamara Kralj +18 more
doaj +2 more sources