Results 1 to 10 of about 102 (68)

Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts

Molecules, 2014
BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies.
Wen-Chung Tsai, Jong-Hwei Su Pang
exaly   +3 more sources

The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats

Brain and Behavior, 2020
Background and purpose We focused on the, yet undescribed, therapy effect of the stable gastric pentadecapeptide BPC 157 in hippocampal ischemia/reperfusion injuries, after bilateral clamping of the common carotid arteries in rats.
Predrag Sikiric, Alenka Boban Blagaic, Borna Vrdoljak   +2 more
exaly   +2 more sources

Antinociceptive Effect of BPC-157 in the Formalin-induced Pain Model [PDF]

Kosin Medical Journal, 2021
Objectives Body protective compound-157 (BPC-157) is a stable gastric pentadecapeptide that has been effective in trials aiming to increase wound healing capabilities and decrease inflammatory cell influx, including studies on the healing of muscles and ...
Sang Yoong Park, So Ron Choi, Jeong Ho Kim, Seung Cheol Lee, Seong Yeop Jeong, Joon Ho Jeong, Tae Young Lee   +6 more
doaj   +1 more source

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing

Frontiers in Pharmacology, 2021
Significance: The antiulcer peptide, stable gastric pentadecapeptide BPC 157 (previously employed in ulcerative colitis and multiple sclerosis trials, no reported toxicity (LD1 not achieved)), is reviewed, focusing on the particular skin wound therapy ...
Sven Seiwerth, Marija Milavic, Jaksa Vukojevic, Slaven Gojkovic, Ivan Krezic, Lovorka Batelja Vuletic, Katarina Horvat Pavlov, Andrea Petrovic, Suncana Sikiric, Hrvoje Vranes, Andreja Prtoric, Helena Zizek, Tajana Durasin, Ivan Dobric, Mario Staresinic, Sanja Strbe, Mario Knezevic, Marija Sola, Antonio Kokot, Marko Sever, Eva Lovric, Anita Skrtic, Alenka Boban Blagaic, Predrag Sikiric   +23 more
doaj   +1 more source

Effect of Pentadecapeptide BPC 157 on Hypercalcaemia in Rats

Liječnički vjesnik, 2023
Isolated from gastric juice stable pentadecapeptide BPC 157 has already shown cytoprotective and organoprotective properties. Beneficial effects of BPC 157 on various organic systems such as cardiovascular, digestive, skeletomuscular system have already ...
Matej Lacković, Helen Marie Chiddenton, Sara Burić   +2 more
doaj   +1 more source

Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine. [PDF]

PLoS ONE, 2015
BPC 157 is a stable gastric pentadecapeptide recently implicated with a role in hemostasis. While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker,
Mirjana Stupnisek, Antonio Kokot, Domagoj Drmic, Masa Hrelec Patrlj, Anita Zenko Sever, Danijela Kolenc, Bozo Radic, Jelena Suran, Davor Bojic, Aleksandar Vcev, Sven Seiwerth, Predrag Sikiric   +11 more
doaj   +1 more source

Stable Gastric Pentadecapeptide BPC 157—Possible Novel Therapy of Glaucoma and Other Ocular Conditions

Pharmaceuticals, 2023
Recently, stable gastric pentadecapeptide BPC 157 therapy by activation of collateral pathways counteracted various occlusion/occlusion-like syndromes, vascular, and multiorgan failure, and blood pressure disturbances in rats with permanent major vessel ...
Predrag Sikiric, Antonio Kokot, Tamara Kralj, Mirna Zlatar, Sanja Masnec, Ratimir Lazic, Kristina Loncaric, Katarina Oroz, Marko Sablic, Marta Boljesic, Marko Antunovic, Suncana Sikiric, Sanja Strbe, Vasilije Stambolija, Lidija Beketic Oreskovic, Ivana Kavelj, Luka Novosel, Slavica Zubcic, Ivan Krezic, Anita Skrtic, Ivana Jurjevic, Alenka Boban Blagaic, Sven Seiwerth, Mario Staresinic   +23 more
doaj   +1 more source

Stable Gastric Pentadecapeptide BPC 157 as a Therapy for the Disable Myotendinous Junctions in Rats

Biomedicines, 2021
(1) Aim: The stable gastric pentadecapeptide BPC 157 is known to heal transected muscle, tendon, and ligament. Thereby, in this study, we investigated the effect of BPC 157 on the dissection of the quadriceps tendon from the quadriceps muscle in rats. (2)
Mladen Japjec, Katarina Horvat Pavlov, Andreja Petrovic, Mario Staresinic, Bozidar Sebecic, Matko Buljan, Hrvoje Vranes, Ana Giljanovic, Domagoj Drmic, Miroslav Japjec, Andreja Prtoric, Eva Lovric, Lovorka Batelja Vuletic, Ivan Dobric, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Sikiric Predrag   +17 more
doaj   +1 more source

Complex Syndrome of the Complete Occlusion of the End of the Superior Mesenteric Vein, Opposed with the Stable Gastric Pentadecapeptide BPC 157 in Rats

Biomedicines, 2021
Background. Gastric pentadecapeptide BPC 157 therapy in rats compensated irremovable occlusion of various vessels and counteracted the consequent multiorgan dysfunction syndromes by activation of the corresponding collateral bypassing loops.
Mario Knezevic, Slaven Gojkovic, Ivan Krezic, Helena Zizek, Hrvoje Vranes, Dominik Malekinusic, Borna Vrdoljak, Tamara Knezevic, Katarina Horvat Pavlov, Domagoj Drmic, Miro Staroveski, Antonija Djuzel, Zoran Rajkovic, Toni Kolak, Eva Lovric, Marija Milavic, Suncana Sikiric, Ivan Barisic, Marijan Tepes, Ante Tvrdeic, Leonardo Patrlj, Sanja Strbe, Marija Sola, Andrej Situm, Antonio Kokot, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +28 more
doaj   +1 more source

BPC 157, L-NAME, L-Arginine, NO-Relation, in the Suited Rat Ketamine Models Resembling “Negative-Like” Symptoms of Schizophrenia

Biomedicines, 2022
We attempted throughout the NO-system to achieve the particular counteraction of the ketamine-induced resembling “negative-like” schizophrenia symptoms in rats using pentadecapeptide BPC 157, and NO-agents, NG-nitro-L-arginine methylester (L-NAME), and ...
Andrea Zemba Cilic, Mladen Zemba, Matija Cilic, Sanja Strbe, Spomenko Ilic, Jaksa Vukojevic, Zoran Zoricic, Igor Filipcic, Antonio Kokot, Ivan Maria Smoday, Iva Rukavina, Alenka Boban Blagaic, Ante Tvrdeic, Bozidar Duplancic, Vasilije Stambolija, Darko Marcinko, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +1 more source