Results 21 to 30 of about 122,466 (202)

The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity [PDF]

Pharmaceuticals
We highlight the particular aspects of the stable gastric pentadecapeptide BPC 157 pleiotropic beneficial activity (not destroyed in human gastric juice, native and stable in human gastric juice, as a cytoprotection mediator holds a response specifically
Predrag Sikiric, Alenka Boban Blagaic, Sanja Strbe, Lidija Beketic Oreskovic, Ivana Oreskovic, Suncana Sikiric, Mario Staresinic, Marko Sever, Antonio Kokot, Ivana Jurjevic, Danijel Matek, Luka Coric, Ivan Krezic, Ante Tvrdeic, Kresimir Luetic, Lovorka Batelja Vuletic, Predrag Pavic, Tomislav Mestrovic, Ivica Sjekavica, Anita Skrtic, Sven Seiwerth   +20 more
doaj   +3 more sources

Stable Gastric Pentadecapeptide BPC 157 May Recover Brain–Gut Axis and Gut–Brain Axis Function [PDF]

Pharmaceuticals, 2023
Conceptually, a wide beneficial effect, both peripherally and centrally, might have been essential for the harmony of brain–gut and gut–brain axes’ function.
Predrag Sikiric, Slaven Gojkovic, Ivan Krezic, Ivan Maria Smoday, Luka Kalogjera, Helena Zizek, Katarina Oroz, Hrvoje Vranes, Vlasta Vukovic, May Labidi, Sanja Strbe, Lidija Baketic Oreskovic, Marko Sever, Marijan Tepes, Mario Knezevic, Ivan Barisic, Vladimir Blagaic, Josipa Vlainic, Ivan Dobric, Mario Staresinic, Anita Skrtic, Ivana Jurjevic, Alenka Boban Blagaic, Sven Seiwerth   +23 more
doaj   +3 more sources

BPC 157, L-NAME, L-Arginine, NO-Relation, in the Suited Rat Ketamine Models Resembling “Negative-Like” Symptoms of Schizophrenia [PDF]

Biomedicines, 2022
We attempted throughout the NO-system to achieve the particular counteraction of the ketamine-induced resembling “negative-like” schizophrenia symptoms in rats using pentadecapeptide BPC 157, and NO-agents, NG-nitro-L-arginine methylester (L-NAME), and ...
Andrea Zemba Cilic, Mladen Zemba, Matija Cilic, Sanja Strbe, Spomenko Ilic, Jaksa Vukojevic, Zoran Zoricic, Igor Filipcic, Antonio Kokot, Ivan Maria Smoday, Iva Rukavina, Alenka Boban Blagaic, Ante Tvrdeic, Bozidar Duplancic, Vasilije Stambolija, Darko Marcinko, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +3 more sources

Tracheocutaneous Fistula Resolved by Pentadecapeptide BPC 157 Therapy Through the NO-System—Triple NO-Agent Approach in Rats [PDF]

Pharmaceuticals
Background/Objectives: This 7-day rat tracheocutaneous fistula study considered the not-studied issues of tracheocutaneous fistula course, wound healing, and fistula in the NO-system relations.
Goran Madzarac, Tomislav Becejac, Toni Penovic, Dominik Drazenovic, Lucija Kralj, Marta Popović Dolic, Suncana Sikiric, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Ana Maria Tubikanec, Mihovil Penavic, Hrvoje Vranes, Ivan Krezic, Mario Kordic, Antun Koprivanac, Tinka Vidovic, Josipa Vlainic, Dinko Stancic Rokotov, Alenka Boban Blagaic, Sven Seiwerth, Anita Skrtic, Predrag Sikiric   +22 more
doaj   +4 more sources

Stable Gastric Pentadecapeptide BPC 157 and Striated, Smooth, and Heart Muscle [PDF]

Biomedicines, 2022
First, we review the definitively severed myotendinous junction and recovery by the cytoprotective stable gastric pentadecapeptide BPC 157 therapy, its healing that might combine both transected and detached tendon and transected muscle, ligament and ...
Mario Staresinic, Mladen Japjec, Hrvoje Vranes, Andreja Prtoric, Helena Zizek, Ivan Krezic, Slaven Gojkovic, Ivan Maria Smoday, Katarina Oroz, Eva Staresinic, Vilim Dretar, Haidi Yago, Marija Milavic, Suncana Sikiric, Eva Lovric, Lovorka Batelja Vuletic, Paris Simeon, Ivan Dobric, Sanja Strbe, Antonio Kokot, Josipa Vlainic, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +24 more
doaj   +3 more sources

Pentadecapeptide BPC 157 as Therapy for Inferior Caval Vein Embolization: Recovery of Sodium Laurate-Post-Embolization Syndrome in Rats [PDF]

Pharmaceuticals, 2023
After inferior caval vein embolization therapy, post-embolization syndrome (sodium laurate 10 mg/kg, 0.1 mL into rat inferior caval vein, assessment at 15, 30, 60 min, prime lung lesions, thromboemboli occluding lung vessels), as a severe occlusion ...
Ivan Maria Smoday, Ivan Krezic, Luka Kalogjera, Vlasta Vukovic, Helena Zizek, Marija Skoro, Katarina Kasnik Kovac, Hrvoje Vranes, Ivan Barisic, Suncana Sikiric, Sanja Strbe, Marijan Tepes, Katarina Oroz, Slavica Zubcic, Mirjana Stupnisek, Lidija Beketic Oreskovic, Ivana Kavelj, Luka Novosel, Matea Prenc, Sanja Barsic Ostojic, Ivan Dobric, Marko Sever, Alenka Boban Blagaic, Anita Skrtic, Mario Staresinic, Ivica Sjekavica, Sven Seiwerth, Predrag Sikiric   +27 more
doaj   +3 more sources

Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury [PDF]

Medicina
Background and Objectives: Ischemia–reperfusion (I/R) injury can affect multiple distant organs following I/R in the lower extremities. BPC-157’s anti-inflammatory and free radical-neutralizing properties suggest its potential in mitigating ischemia ...
Hüseyin Demirtaş, Abdullah Özer, Alperen Kutay Yıldırım, Ali Doğan Dursun, Şaban Cem Sezen, Mustafa Arslan   +5 more
doaj   +3 more sources

Stable Gastric Pentadecapeptide BPC 157 Heals Established Vesicovaginal Fistula and Counteracts Stone Formation in Rats [PDF]

Biomedicines, 2021
With the stable gastric pentadecapeptide BPC 157 therapy known to heal various both external and internal rat fistulas, we attempt to approach vesicovaginal fistula, continuous urine leaking through vagina, bladder stones, and a possible therapy solution
Domagoj Rasic, Anita Zenko Sever, Fran Rasic, Sanja Strbe, Zarko Rasic, Antonija Djuzel, Bozidar Duplancic, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric, Marko Sever   +11 more
doaj   +4 more sources

Occlusion of the Superior Mesenteric Artery in Rats Reversed by Collateral Pathways Activation: Gastric Pentadecapeptide BPC 157 Therapy Counteracts Multiple Organ Dysfunction Syndrome; Intracranial, Portal, and Caval Hypertension; and Aortal Hypotension [PDF]

Biomedicines, 2021
Gastric pentadecapeptide BPC 157 therapy counteracts multiple organ dysfunction syndrome in rats, which have permanent occlusion of the superior mesenteric artery close to the abdominal aorta.
Mario Knezevic, Slaven Gojkovic, Ivan Krezic, Helena Zizek, Dominik Malekinusic, Borna Vrdoljak, Hrvoje Vranes, Tamara Knezevic, Ivan Barisic, Katarina Horvat Pavlov, Domagoj Drmic, Miro Staroveski, Antonija Djuzel, Zoran Rajkovic, Toni Kolak, Ivica Kocman, Eva Lovric, Marija Milavic, Suncana Sikiric, Ante Tvrdeic, Leonardo Patrlj, Sanja Strbe, Antonio Kokot, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +26 more
doaj   +3 more sources

Novel Therapeutic Effects in Rat Spinal Cord Injuries: Recovery of the Definitive and Early Spinal Cord Injury by the Administration of Pentadecapeptide BPC 157 Therapy [PDF]

Current Issues in Molecular Biology, 2022
Recently, marked therapeutic effects pertaining to the recovery of injured rat spinal cords (1 min compression injury of the sacrocaudal spinal cord (S2-Co1) resulting in tail paralysis) appeared after a single intraperitoneal administration of the ...
Darko Perovic, Marija Milavic, Stjepan Dokuzovic, Ivan Krezic, Slaven Gojkovic, Hrvoje Vranes, Igor Bebek, Vide Bilic, Nenad Somun, Ivan Brizic, Ivan Skorak, Klaudija Hriberski, Suncana Sikiric, Eva Lovric, Sanja Strbe, Milovan Kubat, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +3 more sources