Results 11 to 20 of about 122,466 (202)

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing [PDF]

Frontiers in Pharmacology, 2021
Significance: The antiulcer peptide, stable gastric pentadecapeptide BPC 157 (previously employed in ulcerative colitis and multiple sclerosis trials, no reported toxicity (LD1 not achieved)), is reviewed, focusing on the particular skin wound therapy ...
Sven Seiwerth, Marija Milavic, Jaksa Vukojevic, Slaven Gojkovic, Ivan Krezic, Lovorka Batelja Vuletic, Katarina Horvat Pavlov, Andrea Petrovic, Suncana Sikiric, Hrvoje Vranes, Andreja Prtoric, Helena Zizek, Tajana Durasin, Ivan Dobric, Mario Staresinic, Sanja Strbe, Mario Knezevic, Marija Sola, Antonio Kokot, Marko Sever, Eva Lovric, Anita Skrtic, Alenka Boban Blagaic, Predrag Sikiric   +23 more
doaj   +10 more sources

Stable Gastric Pentadecapeptide BPC 157 as a Therapy and Safety Key: A Special Beneficial Pleiotropic Effect Controlling and Modulating Angiogenesis and the NO-System [PDF]

Pharmaceuticals
Although approached through many concepts, the pleiotropic healing issue, specifically, maintaining/reestablishing tissue integrity, remains a central challenge in pharmacology, particularly when the process is misdirected or not properly controlled ...
Predrag Sikiric, Sven Seiwerth, Anita Skrtic, Mario Staresinic, Sanja Strbe, Antonia Vuksic, Suncana Sikiric, Dinko Bekic, Dragan Soldo, Boris Grizelj, Luka Novosel, Lidija Beketic Oreskovic, Ivana Oreskovic, Mirjana Stupnisek, Alenka Boban Blagaic, Ivan Dobric   +15 more
doaj   +5 more sources

Innate Vascular Failure by Application of Neuroleptics, Amphetamine, and Domperidone Rapidly Induced Severe Occlusion/Occlusion-like Syndromes in Rats and Stable Gastric Pentadecapeptide BPC 157 as Therapy [PDF]

Pharmaceuticals, 2023
Even before behavioral disturbances, neuroleptics, amphetamine, and domperidone application rapidly emerged severe occlusion/occlusion-like syndrome, shared innate vascular and multiorgan failure in rats, comparable to occlusion/occlusion-like syndrome ...
Sanja Strbe, Ivan Maria Smoday, Ivan Krezic, Luka Kalogjera, Vlasta Vukovic, Helena Zizek, Slaven Gojkovic, Hrvoje Vranes, Ivan Barisic, Suncana Sikiric, Marijan Tepes, Katarina Oroz, Filip Brkic, Martin Drinkovic, Lidija Beketic Oreskovic, Jelena Popic, Alenka Boban Blagaic, Anita Skrtic, Mario Staresinic, Sven Seiwerth, Predrag Sikiric   +20 more
doaj   +5 more sources

Pentadecapeptide BPC 157 and the central nervous system [PDF]

Neural Regeneration Research, 2022
We reviewed the pleiotropic beneficial effects of the stable gastric pentadecapeptide BPC 157, three very recent demonstrations that may be essential in the gut-brain and brain-gut axis operation, and therapy application in the central nervous system ...
Jakša Vukojevic, Marija Milavić, Darko Perović, Spomenko Ilić, Andrea Zemba Čilić, Nataša Đuran, Sanja Štrbe, Zoran Zoričić, Igor Filipčić, Petrana Brečić, Sven Seiverth, Predrag Sikirić   +11 more
doaj   +6 more sources

Stable Gastric Pentadecapeptide BPC 157 as a Therapy for the Disable Myotendinous Junctions in Rats [PDF]

Biomedicines, 2021
(1) Aim: The stable gastric pentadecapeptide BPC 157 is known to heal transected muscle, tendon, and ligament. Thereby, in this study, we investigated the effect of BPC 157 on the dissection of the quadriceps tendon from the quadriceps muscle in rats. (2)
Mladen Japjec, Katarina Horvat Pavlov, Andreja Petrovic, Mario Staresinic, Bozidar Sebecic, Matko Buljan, Hrvoje Vranes, Ana Giljanovic, Domagoj Drmic, Miroslav Japjec, Andreja Prtoric, Eva Lovric, Lovorka Batelja Vuletic, Ivan Dobric, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Sikiric Predrag   +17 more
doaj   +5 more sources

Stable Gastric Pentadecapeptide BPC 157 Therapy of Rat Glaucoma [PDF]

Biomedicines, 2021
Cauterization of three episcleral veins (open-angle glaucoma model) induces venous congestion and increases intraocular pressure in rats. If not upgraded, one episcleral vein is regularly unable to acquire and take over the whole function, and glaucoma ...
Tamara Kralj, Antonio Kokot, Mirna Zlatar, Sanja Masnec, Katarina Kasnik Kovac, Marija Milkovic Perisa, Lovorka Batelja Vuletic, Ana Giljanovic, Sanja Strbe, Suncana Sikiric, Slaven Balog, Bojan Sontacchi, Dijana Sontacchi, Matko Buljan, Eva Lovric, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +7 more sources

Stable Gastric Pentadecapeptide BPC 157—Possible Novel Therapy of Glaucoma and Other Ocular Conditions [PDF]

Pharmaceuticals, 2023
Recently, stable gastric pentadecapeptide BPC 157 therapy by activation of collateral pathways counteracted various occlusion/occlusion-like syndromes, vascular, and multiorgan failure, and blood pressure disturbances in rats with permanent major vessel ...
Predrag Sikiric, Antonio Kokot, Tamara Kralj, Mirna Zlatar, Sanja Masnec, Ratimir Lazic, Kristina Loncaric, Katarina Oroz, Marko Sablic, Marta Boljesic, Marko Antunovic, Suncana Sikiric, Sanja Strbe, Vasilije Stambolija, Lidija Beketic Oreskovic, Ivana Kavelj, Luka Novosel, Slavica Zubcic, Ivan Krezic, Anita Skrtic, Ivana Jurjevic, Alenka Boban Blagaic, Sven Seiwerth, Mario Staresinic   +23 more
doaj   +3 more sources

Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review [PDF]

Pharmaceuticals
BPC 157, known as the “Body Protection Compound”, is a pentadecapeptide isolated from human gastric juice that demonstrated its pleiotropic beneficial effects in various preclinical models mimicking medical conditions, such as tissue injury, inflammatory
Michalina Józwiak, Marta Bauer, Wojciech Kamysz, Patrycja Kleczkowska   +3 more
doaj   +3 more sources

Antiarrhythmic Sotalol, Occlusion/Occlusion-like Syndrome in Rats, and Stable Gastric Pentadecapeptide BPC 157 Therapy [PDF]

Pharmaceuticals, 2023
We focused on the first demonstration that antiarrhythmics, particularly class II and class III antiarrhythmic and beta-blocker sotalol can induce severe occlusion/occlusion-like syndrome in rats.
Ivica Premuzic Mestrovic, Ivan Maria Smoday, Luka Kalogjera, Ivan Krezic, Helena Zizek, Hrvoje Vranes, Vlasta Vukovic, Katarina Oroz, Ivan Skorak, Ivan Brizic, Klaudija Hriberski, Luka Novosel, Ivana Kavelj, Ivan Barisic, Lidija Beketic Oreskovic, Slavica Zubcic, Sanja Strbe, Tomislav Mestrovic, Predrag Pavic, Mario Staresinic, Anita Skrtic, Alenka Boban Blagaic, Sven Seiwerth, Predrag Sikiric   +23 more
doaj   +3 more sources

Stable Gastric Pentadecapeptide BPC 157 and Intestinal Anastomoses Therapy in Rats-A Review. [PDF]

Pharmaceuticals (Basel)
By introducing the healing of many distinctive anastomoses by BPC 157 therapy, this review practically deals with the concept of the resection and reconnection of the hollow parts of the gastrointestinal tract as one of the cornerstones of visceral ...
Bajramagic S, Sever M, Rasic F, Staresinic M, Skrtic A, Beketic Oreskovic L, Oreskovic I, Strbe S, Loga Zec S, Hrabar J, Coric L, Prenc M, Blagaic V, Brcic K, Boban Blagaic A, Seiwerth S, Sikiric P.   +16 more
europepmc   +4 more sources