Results 11 to 20 of about 830 (135)

Stable Gastric Pentadecapeptide BPC 157 Therapy of Rat Glaucoma [PDF]

Biomedicines, 2021
Cauterization of three episcleral veins (open-angle glaucoma model) induces venous congestion and increases intraocular pressure in rats. If not upgraded, one episcleral vein is regularly unable to acquire and take over the whole function, and glaucoma ...
Tamara Kralj, Antonio Kokot, Mirna Zlatar, Sanja Masnec, Katarina Kasnik Kovac, Marija Milkovic Perisa, Lovorka Batelja Vuletic, Ana Giljanovic, Sanja Strbe, Suncana Sikiric, Slaven Balog, Bojan Sontacchi, Dijana Sontacchi, Matko Buljan, Eva Lovric, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +7 more sources

Effect of Pentadecapeptide BPC 157 on Hypercalcaemia in Rats

Liječnički vjesnik, 2023
Isolated from gastric juice stable pentadecapeptide BPC 157 has already shown cytoprotective and organoprotective properties. Beneficial effects of BPC 157 on various organic systems such as cardiovascular, digestive, skeletomuscular system have already ...
Matej Lacković, Helen Marie Chiddenton, Sara Burić   +2 more
doaj   +2 more sources

Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts

Molecules, 2014
BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies.
Wen-Chung Tsai, Tsai Wen-Chung, Jong-Hwei Su Pang   +2 more
exaly   +3 more sources

Stable Gastric Pentadecapeptide BPC 157 May Recover Brain–Gut Axis and Gut–Brain Axis Function [PDF]

Pharmaceuticals, 2023
Conceptually, a wide beneficial effect, both peripherally and centrally, might have been essential for the harmony of brain–gut and gut–brain axes’ function.
Predrag Sikiric, Slaven Gojkovic, Ivan Krezic, Ivan Maria Smoday, Luka Kalogjera, Helena Zizek, Katarina Oroz, Hrvoje Vranes, Vlasta Vukovic, May Labidi, Sanja Strbe, Lidija Baketic Oreskovic, Marko Sever, Marijan Tepes, Mario Knezevic, Ivan Barisic, Vladimir Blagaic, Josipa Vlainic, Ivan Dobric, Mario Staresinic, Anita Skrtic, Ivana Jurjevic, Alenka Boban Blagaic, Sven Seiwerth   +23 more
doaj   +2 more sources

BPC 157 Therapy: Targeting Angiogenesis and Nitric Oxide’s Cytotoxic and Damaging Actions, but Maintaining, Promoting, or Recovering Their Essential Protective Functions. Comment on Józwiak et al. Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review. Pharmaceuticals 2025, 18, 185 [PDF]

Pharmaceuticals
The healing issue is a central, not completely understood, problem in pharmacology, approached by many concepts. One of the most well-known is Robert’s and Szabo’s concept of cytoprotection, which holds innate cell (epithelial (Robert), endothelial ...
Predrag Sikiric, Sven Seiwerth, Anita Skrtic, Mario Staresinic, Sanja Strbe, Antonia Vuksic, Suncana Sikiric, Dinko Bekic, Dragan Soldo, Boris Grizelj, Luka Novosel, Lidija Beketic Oreskovic, Ivana Oreskovic, Mirjana Stupnisek, Alenka Boban Blagaic, Ivan Dobric   +15 more
doaj   +2 more sources

Stable Gastric Pentadecapeptide BPC 157 Therapy for Primary Abdominal Compartment Syndrome in Rats [PDF]

Frontiers in Pharmacology, 2021
Recently, the stable gastric pentadecapeptide BPC 157 was shown to counteract major vessel occlusion syndromes, i.e., peripheral and/or central occlusion, while activating particular collateral pathways.
Marijan Tepes, Marijan Tepes, Marijan Tepes, Marijan Tepes, Slaven Gojkovic, Ivan Krezic, Helena Zizek, Hrvoje Vranes, Zrinko Madzar, Goran Santak, Lovorka Batelja, Marija Milavic, Suncana Sikiric, Ivica Kocman, Karol Simonji, Mariam Samara, Mario Knezevic, Ivan Barisic, Eva Lovric, Sanja Strbe, Antonio Kokot, Ivica Sjekavica, Toni Kolak, Anita Skrtic, Sven Seiwerth, Alenka Boban Blagaic, Predrag Sikiric   +26 more
doaj   +2 more sources

Pentadecapeptide BPC 157 as Therapy for Inferior Caval Vein Embolization: Recovery of Sodium Laurate-Post-Embolization Syndrome in Rats [PDF]

Pharmaceuticals, 2023
After inferior caval vein embolization therapy, post-embolization syndrome (sodium laurate 10 mg/kg, 0.1 mL into rat inferior caval vein, assessment at 15, 30, 60 min, prime lung lesions, thromboemboli occluding lung vessels), as a severe occlusion ...
Ivan Maria Smoday, Ivan Krezic, Luka Kalogjera, Vlasta Vukovic, Helena Zizek, Marija Skoro, Katarina Kasnik Kovac, Hrvoje Vranes, Ivan Barisic, Suncana Sikiric, Sanja Strbe, Marijan Tepes, Katarina Oroz, Slavica Zubcic, Mirjana Stupnisek, Lidija Beketic Oreskovic, Ivana Kavelj, Luka Novosel, Matea Prenc, Sanja Barsic Ostojic, Ivan Dobric, Marko Sever, Alenka Boban Blagaic, Anita Skrtic, Mario Staresinic, Ivica Sjekavica, Sven Seiwerth, Predrag Sikiric   +27 more
doaj   +2 more sources

Novel Therapeutic Effects in Rat Spinal Cord Injuries: Recovery of the Definitive and Early Spinal Cord Injury by the Administration of Pentadecapeptide BPC 157 Therapy [PDF]

Current Issues in Molecular Biology, 2022
Recently, marked therapeutic effects pertaining to the recovery of injured rat spinal cords (1 min compression injury of the sacrocaudal spinal cord (S2-Co1) resulting in tail paralysis) appeared after a single intraperitoneal administration of the ...
Darko Perovic, Marija Milavic, Stjepan Dokuzovic, Ivan Krezic, Slaven Gojkovic, Hrvoje Vranes, Igor Bebek, Vide Bilic, Nenad Somun, Ivan Brizic, Ivan Skorak, Klaudija Hriberski, Suncana Sikiric, Eva Lovric, Sanja Strbe, Milovan Kubat, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +2 more sources

The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity [PDF]

Pharmaceuticals
We highlight the particular aspects of the stable gastric pentadecapeptide BPC 157 pleiotropic beneficial activity (not destroyed in human gastric juice, native and stable in human gastric juice, as a cytoprotection mediator holds a response specifically
Predrag Sikiric, Alenka Boban Blagaic, Sanja Strbe, Lidija Beketic Oreskovic, Ivana Oreskovic, Suncana Sikiric, Mario Staresinic, Marko Sever, Antonio Kokot, Ivana Jurjevic, Danijel Matek, Luka Coric, Ivan Krezic, Ante Tvrdeic, Kresimir Luetic, Lovorka Batelja Vuletic, Predrag Pavic, Tomislav Mestrovic, Ivica Sjekavica, Anita Skrtic, Sven Seiwerth   +20 more
doaj   +2 more sources

The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats

Brain and Behavior, 2020
Background and purpose We focused on the, yet undescribed, therapy effect of the stable gastric pentadecapeptide BPC 157 in hippocampal ischemia/reperfusion injuries, after bilateral clamping of the common carotid arteries in rats.
Predrag Sikiric, Alenka Boban Blagaic, Borna Vrdoljak   +2 more
exaly   +2 more sources