Results 31 to 40 of about 830 (135)
Hepatoprotective effects of BPC-157 - paracetamol overdose
Liječnički vjesnik, 2023 Paracetamol, also known as acetaminophen, is a widely used medication to treat pain and fever. As it’s one of the over-the-counter medications, it’s easily accessible to everyone.
Sara Burić +2 more
doaj +2 more sources
Conventional Antiarrhythmics Class I–IV, Late INa Inhibitors, IKs Enhancers, RyR2 Stabilizers, Gap Junction Modulators, Atrial-Selective Antiarrhythmics, and Stable Gastric Pentadecapeptide BPC 157 as Useful Cytoprotective Therapy in Arrhythmias [PDF]
PharmaceuticalsThis review examines and hypothesizes cytoprotection as a conceptual therapeutic criterion for antiarrhythmic drugs, referring to the possibility of suppressing arrhythmias while avoiding adverse electrophysiological or systemic effects.
Predrag Sikiric +22 more
doaj +2 more sources
BPC 157 as Potential Treatment for COVID-19. [PDF]
Med Hypotheses, 2021 The emergence of coronavirus disease (COVID-19) in China at the end of 2019 has caused a large global outbreak. COVID-19 is largely seen as a thrombotic and vascular disease targeting endothelial cells (ECs) throughout the body that can provoke the breakdown of central vascular functions.
Deek SA.
europepmc +3 more sources
Antinociceptive Effect of BPC-157 in the Formalin-induced Pain Model [PDF]
Kosin Medical Journal, 2021 Objectives Body protective compound-157 (BPC-157) is a stable gastric pentadecapeptide that has been effective in trials aiming to increase wound healing capabilities and decrease inflammatory cell influx, including studies on the healing of muscles and ...
Sang Yoong Park +6 more
doaj +1 more source
Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine. [PDF]
PLoS ONE, 2015 BPC 157 is a stable gastric pentadecapeptide recently implicated with a role in hemostasis. While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker,
Mirjana Stupnisek +11 more
doaj +1 more source
Novelties regarding pentadecapeptide BPC-157
Biomedicine and surgery, 2021 Stable gastric pentadecapeptide BPC-157 is a novel anti-ulcer peptide, used in trials for the treatment of ulcerative colitis and now multiple sclerosis. That fifteen amino acid molecule is likely mediator of Robert’s stomach cytoprotection/adaptive cytoprotection and organoprotection, as well as a novel mediator of Selye’s stress coping response, to ...
Amić, Fedor +2 more
openaire +3 more sources
Biomedicines, 2021 Background. Gastric pentadecapeptide BPC 157 therapy in rats compensated irremovable occlusion of various vessels and counteracted the consequent multiorgan dysfunction syndromes by activation of the corresponding collateral bypassing loops.
Mario Knezevic +28 more
doaj +1 more source
BPC-157 and Its Novel Hybrid Analogs as Inhibitors of Acetylcholinesterase. [PDF]
Int J Mol SciAcetylcholinesterase (AChE) inhibition remains a key therapeutic strategy in the management of neurodegenerative disorders such as Alzheimer’s disease. In this study, the inhibitory potential of the gastric pentadecapeptide BPC-157 and two newly designed hybrid analogs, CIARA-1 and CIARA-2, was investigated for the first time.
Jelińska J +7 more
europepmc +2 more sources
Gut and Liver, 2020 We reviewed again the significance of the stable gastric pentadecapeptide BPC 157 as a likely mediator of Robert’s stomach cytoprotection/adaptive cytoprotection and organoprotection and as novel mediator of Selye’s stress coping response to reestablish ...
Predrag Sikiric +11 more
doaj +1 more source
Emergency Medicine International, 2020 Recently, the pentadecapeptide BPC 157-induced counteraction of bupivacaine cardiotoxicity has been reported. Medication includes (i) lidocaine-induced local anesthesia via intraplantar application and axillary and spinal (L4-L5) intrathecal block, (ii ...
Marin Lozic +16 more
doaj +1 more source