Results 31 to 40 of about 258,688 (126)

Robert’s Intragastric Alcohol-Induced Gastric Lesion Model as an Escalated General Peripheral and Central Syndrome, Counteracted by the Stable Gastric Pentadecapeptide BPC 157 [PDF]

Biomedicines, 2021
We redefined Robert’s prototypical cytoprotection model, namely the intragastric administration of 96% alcohol in order to generate a general peripheral and central syndrome similar to that which occurs when major central or peripheral veins are occluded
Slaven Gojkovic, Ivan Krezic, Hrvoje Vranes, Helena Zizek, Domagoj Drmic, Lovorka Batelja Vuletic, Marija Milavic, Suncana Sikiric, Irma Stilinovic, Paris Simeon, Mario Knezevic, Toni Kolak, Marijan Tepes, Karol Simonji, Sanja Strbe, Nora Nikolac Gabaj, Ivan Barisic, Emma Grace Oreskovic, Eva Lovric, Antonio Kokot, Anita Skrtic, Alenka Boban Blagaic, Sven Seiwerth, Predrag Sikiric   +23 more
doaj   +2 more sources

Stable Gastric Pentadecapeptide BPC 157, Robert’s Stomach Cytoprotection/Adaptive Cytoprotection/Organoprotection, and Selye’s Stress Coping Response: Progress, Achievements, and the Future [PDF]

Gut and Liver, 2020
We reviewed again the significance of the stable gastric pentadecapeptide BPC 157 as a likely mediator of Robert’s stomach cytoprotection/adaptive cytoprotection and organoprotection and as novel mediator of Selye’s stress coping response to reestablish ...
Predrag Sikiric, Ki-Baik Hahm, Alenka Boban Blagaic, Ante Tvrdeic, Katarina Horvat Pavlov, Andrea Petrovic, Antonio Kokot, Slaven Gojkovic, Ivan Krezic, Domagoj Drmic, Rudolf Rucman, Sven Seiwerth   +11 more
doaj   +2 more sources

Tendon, Ligament, and Muscle Injury, Osteotendinous, Myotendinous, and Muscle-to-Bone Junction Therapy Perspectives with Growth Factors and Stable Gastric Pentadecapeptide BPC 157—A Review [PDF]

Pharmaceuticals
As a novel theoretical and practical advantage, preclinical to clinical evidence, this systematic review of PRP, growth factors, and stable gastric pentadecapeptide BPC 157 efficacy in complex musculoskeletal and junctional injuries emphasizes the ...
Danijel Matek, Irena Matek, Mladen Japjec, Mirta Matek, Jakov Prenc, Borna Staresinic, Eva Staresinic, Andreja Prtoric, Suncana Sikiric, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic, Ivan Bojanic, Ivan Dobric, Mario Staresinic   +20 more
doaj   +2 more sources

Tracheocutaneous Fistula Resolved by Pentadecapeptide BPC 157 Therapy Through the NO-System—Triple NO-Agent Approach in Rats [PDF]

Pharmaceuticals
Background/Objectives: This 7-day rat tracheocutaneous fistula study considered the not-studied issues of tracheocutaneous fistula course, wound healing, and fistula in the NO-system relations.
Goran Madzarac, Tomislav Becejac, Toni Penovic, Dominik Drazenovic, Lucija Kralj, Marta Popović Dolic, Suncana Sikiric, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Ana Maria Tubikanec, Mihovil Penavic, Hrvoje Vranes, Ivan Krezic, Mario Kordic, Antun Koprivanac, Tinka Vidovic, Josipa Vlainic, Dinko Stancic Rokotov, Alenka Boban Blagaic, Sven Seiwerth, Anita Skrtic, Predrag Sikiric   +22 more
doaj   +2 more sources

Pentadecapeptide BPC 157 and Rac 1 inhibitors [PDF]

, 2016
UVOD: Rac1 je mali signalizirajući G-protein koji može aktivirati NF-kappaB. Pentadekapeptid BPC 157 smanjuje transkripciju Vcam-1 u NF-kappaB signalnom putu kao i neki NF-kappaB inhibitori te suprimira da ERK inducira Vcam-1 preko NF-kappaB aktivacije.
Vidović, Tinka
core   +2 more sources

Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats [PDF]

Journal of Orthopaedic Surgery and Research, 2019
Background We focused on the therapeutic effects of the stable gastric pentadecapeptide BPC 157 in spinal cord injury using a rat model. BPC 157, of which the LD1 has not been achieved, has been implemented as an anti-ulcer peptide in inflammatory bowel ...
Darko Perovic, Danijela Kolenc, Vide Bilic, Nenad Somun, Domagoj Drmic, Esmat Elabjer, Gojko Buljat, Sven Seiwerth, Predrag Sikiric   +8 more
doaj   +2 more sources

Pentadecapeptide BPC 157 Shortens Duration of Tetracaine- and Oxybuprocaine-Induced Corneal Anesthesia in Rats [PDF]

Acta Clinica Croatica, 2020
We focused on the relationship of 0.5% tetracaine- and 0.4% oxybuprocaine-induced corneal anesthesia in rats, and pentadecapeptide BPC 157 (0.4 μg/eye), along with nitric oxide synthase (NOS) inhibitor N(gamma)-nitro-L-arginine methyl ester (L-NAME) (0.1
Ivan Mirković, Tamara Kralj, Marin Lozić, Vasilije Stambolija, Josip Kovačević, Luka Vrdoljak, Mirna Zlatar, Kristina Milanović, Domagoj Drmić, Jurica Predović, Sanja Masnec, Matija Jurjević, Mladen Bušić, Sven Seiwerth, Antonio Kokot, Predrag Sikirić   +15 more
doaj   +2 more sources

Occlusion of the Superior Mesenteric Artery in Rats Reversed by Collateral Pathways Activation: Gastric Pentadecapeptide BPC 157 Therapy Counteracts Multiple Organ Dysfunction Syndrome; Intracranial, Portal, and Caval Hypertension; and Aortal Hypotension [PDF]

Biomedicines, 2021
Gastric pentadecapeptide BPC 157 therapy counteracts multiple organ dysfunction syndrome in rats, which have permanent occlusion of the superior mesenteric artery close to the abdominal aorta.
Mario Knezevic, Slaven Gojkovic, Ivan Krezic, Helena Zizek, Dominik Malekinusic, Borna Vrdoljak, Hrvoje Vranes, Tamara Knezevic, Ivan Barisic, Katarina Horvat Pavlov, Domagoj Drmic, Miro Staroveski, Antonija Djuzel, Zoran Rajkovic, Toni Kolak, Ivica Kocman, Eva Lovric, Marija Milavic, Suncana Sikiric, Ante Tvrdeic, Leonardo Patrlj, Sanja Strbe, Antonio Kokot, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +26 more
doaj   +2 more sources

Spinal Instability in Rats Counteracted by Pentadecapeptide BPC 157 [PDF]

The FASEB Journal, 2019
To induce spinal instability, we focused on bilateral facetectomy in rats and possible therapeutic benefit with the stable gastric pentadecapeptide BPC 157 given in the drinking water. Recently, using a well‐designed rat model (L2‐L3 compression), we demonstrated that the stable gastric pentadecapeptide BPC 157 improved the spinal cord injury (FASEB J ...
Dokuzovic, Stjepan, Bebek, Igor, Perovic, Darko, Bilic, Vide, Corluka, Stipe, Krezic, Ivan, Durasin, Tajana, Drmic, Domagoj, Seiwerth, Sven, Sikiric, Predrag   +9 more
core   +3 more sources

Over-Dose Lithium Toxicity as an Occlusive-like Syndrome in Rats and Gastric Pentadecapeptide BPC 157 [PDF]

Biomedicines, 2021
Dean Strinic, Ivan Krezić, Sven Seiwerth   +2 more
exaly   +2 more sources