Results 111 to 120 of about 120,051 (368)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Locking mechanism for orthopedic braces [PDF]

open access: yes
A locking mechanism for orthopedic braces is described which automatically prevents or permits the relative pivotable movement between a lower brace member and an upper brace member.
Epps, C. H., Jr., I-Lechao, J.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Evaluation of the shear bond strength of the Orthobond composite under different conditions [PDF]

open access: yesRGO: Revista Gaúcha de Odontologia, 2008
Objective: Evaluate the shear bond strength of metal brackets bonded with Orthobond composite (Dental Morelli Ltda, Sorocaba, Brazil) under different enamel surface conditions.
Antônio Carlos de Oliveira Ruellas   +4 more
doaj  

On the passage from finite braces to pre-Lie rings [PDF]

open access: yesAdvances in Mathematics, 2022
A. Smoktunowicz
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Effect of Wearable Passive Back Support Exoskeleton on the Peak Muscle Activation of the Erector Spinae Muscles During Lifting

open access: yesPhysical Therapy Korea
Background: Using wearable passive back-support exoskeletons in workplace has attracted attention as devices that support the posture of workers, enhance their physical capabilities, and reduce physical risk factors.
Hee-Eun Ahn, Tae-Lim Yoon
doaj   +1 more source

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