Microbial Pathogenesis, 2020 Swine dysentery (SD) is a global, production-limiting disease of pigs in commercial farms. It is associated with infection by Brachyspira hyodysenteriae and B. hampsonii, and characterized by mucohaemorrhagic diarrhea and colitis, SD prevention, treatment or control relies heavily on antimicrobials as no commercial vaccines are available.
Matheus O, Costa, John C S, Harding
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Role of sialic acid in brachyspira hyodysenteriae adhesion to pig colonic mucins [PDF]
, 2019 Infection with Brachyspira hyodysenteriae results in mucoid hemorrhagic diarrhea. This pathogen is associated with the colonic mucus layer, mainly composed of mucins. Infection regulates mucin O-glycosylation in the colon and increases mucin secretion as
Haesebrouck, Freddy +3 more
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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for rapid identification of Brachyspira species isolated from swine, including the newly described “Brachyspira hampsonii” [PDF]
Journal of Veterinary Diagnostic Investigation, 2014 The Brachyspira species traditionally associated with swine dysentery and other diarrheal diseases in pigs are Brachyspira hyodysenteriae, Brachyspira pilosicoli, and, to a lesser extent, Brachyspira murdochii. “ Brachyspira hampsonii” is a recently proposed novel species that causes clinical disease similar to that caused by B. hyodysenteriae. Matrix-
Hallie L, Warneke +4 more
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Methods for improving diagnostic techniques used for the identification and isolation of Brachyspira species from swine [PDF]
, 2017 Brachyspira hyodysenteriae is the main etiological agent of swine dysentery and is an important species for ongoing research into the field. Swine dysentery (SD) is also caused by Brachyspira hampsonii and Brachyspira suanatina, which have recently been ...
Warneke, Hallie
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Brachyspira pilosicoli-induced avian intestinal spirochaetosis [PDF]
, 2015 Avian intestinal spirochetosis (AIS) is a common disease occurring in poultry that can be caused by Brachyspira pilosicoli, a Gram-negative bacterium of the order Spirochaetes. During AIS, this opportunistic pathogen colonises the lower gastrointestinal (
Eurostat +7 more
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Low occurrence of Brachyspira hyodysenteriae in Swiss pig herds with diarrhoea. [PDF]
, 2021 In the Swiss pig population, only four sequence types (ST6, ST66, ST196, ST197) of Brachyspira ( B .) hyodysenteriae , an agent of Swine Dysentery (SD), have been so far detected suggesting a limited number of sources of B.
Arnold, M. +9 more
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A novel multiplex qPCR targeting 23S rDNA for diagnosis of swine dysentery and porcine intestinal spirochaetosis [PDF]
, 2016 Figure S1. Consensus sequence alignment of the target DNA region within 23S ribosomal DNA. Primers (Brachy primer for. and Brachy primer rev.) on the target DNA are marked in grey. The probe for B. hyodysenteriae (Probe_hyo) is highlighted in yellow, the
Anna Borgström +5 more
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An in silico reverse vaccinology study of Brachyspira pilosicoli, the causative organism of intestinal spirochaetosis, to identify putative vaccine candidates [PDF]
, 2022 Brachyspira pilosicoli is a zoonotic bacterium that can cause intestinal spirochaetosis (IS) in avian species (AIS), pigs (PIS) and humans (HIS). In the absence of vaccines to prevent infections, we used genome-based reverse vaccinology (RV) to identify ...
Christodoulides, Myron +5 more
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Pathophysiological Effects of Brachyspira Species on Ion Transport Within the Porcine Colon Resulting in Diarrheal Disease [PDF]
, 2019 Swine dysentery, a production limiting diarrhea in swine, is responsible for profound economic loss annually. Brachyspira hyodysenteriae is the etiological agent responsible for colonization of the colon and development of classical swine dysentery. Like
Enns, Cole Brett
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Characterization of wild-type and laboratory attenuated “Brachyspira hampsonii” [PDF]
, 2017 This thesis aimed to characterize Western Canadian “Brachyspira hampsonii” clinical isolates and to develop and characterize an attenuated “B. hampsonii” vaccine candidate. Clinical “B.
Perez, Jason Byron DS 1992-
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